Kangra, India

The Central University of Himachal Pradesh is operating from temporary academic block which is established at Shahpur,Himachal Pradesh. The university will have its two permanent campuses viz Beas campus at Dehra and Dhauladhar campus at Dharamshala. This university was previously allotted to Dehra town but due to political propaganda same was shifted to Shahpur for temporary classes although enough space was provided at Dehra and later divided into two location for political benefits. The university was founded in 2009 as a result of the government's policy to establish Central Universities in each of the states that do not already have a central university. Wikipedia.

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Rana A.,Central University of Himachal Pradesh | Rub A.,Jamia Millia Islamia University | Akhter Y.,Central University of Himachal Pradesh
Journal of Molecular Recognition | Year: 2015

Mycobacterium avium subsp. paratuberculosis (MAP) is an etiological agent of chronic inflammation of the intestine among ruminants and humans. Currently, there are no effective vaccines and sensitive diagnostic tests available for its control and detection. For this, it is of paramount importance to identify the MAP antigens, which may be immunologically recognized by the host immune system. To address this challenge, we performed identification of the immunogenic epitopes in the MAP outer membrane proteins (OMPs). We have previously identified 57 MAP proteins as OMPs [Rana A, Rub A, Akhter Y. 2014. Molecular BioSystems, 10:2329-2337] and have evaluated them for the epitope selection and analysis employing a computational approach. Thirty-five MAP OMPs are reported with nine-mer peptides showing high binding affinity to major histocompatibility complex (MHC) class I molecules and 28 MAP OMPs with 15-mer peptides of high binding affinity for MHC class II molecules. The presence of MHC binding epitopes indicates the potential cell-mediated immune response inducing capacity of these MAP OMPs in infected host. To further investigate the humoral response inducing properties of OMPs of MAP, we report potential B cell epitopes based on the sequences of peptide antigens and their molecular structures. We also report 10 proteins having epitopes for both B and T cells representing potential candidates which may invoke both humoral and cellular immune responses in the host. These findings will greatly accelerate and expedite the formulation of effective and cost-efficient vaccines and diagnostic tests against MAP infection. © 2015 John Wiley & Sons, Ltd.

Rana A.,Central University of Himachal Pradesh | Rub A.,Jamia Millia Islamia University | Akhter Y.,Central University of Himachal Pradesh
Molecular BioSystems | Year: 2014

Outer membrane proteins (OMPs) in eubacteria have several important roles, which range from membrane transport to the host-pathogen interactions. These are directly involved in pathogen attachment, entry and activation of several pathogen-induced signaling cascades in the cell. The cardinal structural features of OMPs include the presence of a β-barrel, a signal peptide and the absence of the transmembrane helix. This is the first report on proteome-wide identification of OMPs of ruminant pathogen, Mycobacterium avium subsp. paratuberculosis (MAP). The complete proteome of MAP was analyzed using a pipeline of algorithms, which screens the amino acid sequences and structural features shared by OMPs in other bacteria. Secondary structure of these proteins is also analyzed and scores are calculated for amphiphilic β-strands. From the set of 588 exported proteins, 264 proteins are predicted to be inner membrane proteins while 83 proteins are identified as potential OMPs in MAP. Finally, this study identified 57 proteins as top candidates, on the basis of computed isoelectric points, as the core set of OMPs. Significantly, the resulting data for OMPs are not only useful in designing novel vaccines but may also open avenues for the development of early serodiagnostic tools for MAP. © 2014 the Partner Organisations.

Pant D.,Central University of Himachal Pradesh
International Journal of Life Cycle Assessment | Year: 2013

Purpose: E-waste is the most rapidly growing problem throughout the world, which has serious future concerns over its management and recycling. This article proposes a simple approach for future e-waste projection which can be obtained by using life-span data of various electronic items along with incorporation of population statistics. Methods: For this purpose, 7-year sales data of electronic items were collected, which is then used to generate various mathematical equations. These mathematical relations are then modified by incorporating life-span and population data. Results and discussion: By comparing sales data with their life-span (average) and population statistics, future e-waste can be quantified both in terms of specified area under investigation and proposed estimation area. The following equation is thus proposed: E - waste (In terms of quantity) = [m {Waste projection year - Life span} - Initial data collection year + C] × Population of estimation area/ Population of study area Where m and C can be obtained from plotting year-wise sales data over Excel sheet. Conclusions: Local as well as global projection of future e-waste can be possible with the help of final equation. © 2013 Springer-Verlag Berlin Heidelberg.

Sunil,National Institute of Technology Hamirpur | Devi R.,National Institute of Technology Hamirpur | Mahajan A.,Central University of Himachal Pradesh
International Communications in Heat and Mass Transfer | Year: 2011

We show that the global nonlinear stability threshold for convection in a couple-stress fluid is exactly the same as the linear instability boundary. This optimal result is important because it shows that linearized instability theory has captured completely the physics of the onset of convection. It is also found that the couple-stress fluid is thermally more stable than the ordinary viscous fluid and then the effect of couple stress parameter on the onset of convection is also analyzed. © 2011 Elsevier Ltd.

Pant D.,Central University of Himachal Pradesh | Singh P.,Uttarakhand Technical University
Environmental Science and Pollution Research | Year: 2014

Pollution resulting from hazardous glass (HG) is widespread across the globe, both in terms of quantity and associated health risks. In waste cathode ray tube (CRT) and fluorescent lamp glass, mercury and lead are present as the major pollutants. The current review discusses the issues related to quantity and associated risk from the pollutant present in HG and proposes the chemical, biological, thermal, hybrid, and nanotechniques for its management. The hybrid is one of the upcoming research models involving the compatible combination of two or more techniques for better and efficient remediation. Thermal mercury desorption starts at 100 °C but for efficient removal, the temperature should be >460 °C. Involvement of solar energy for this purpose makes the research more viable and ecofriendly. Nanoparticles such as Fe, Se, Cu, Ni, Zn, Ag, and WS2 alone or with its formulation can immobilize heavy metals present in HG by involving a redox mechanism. Straight-line equation from year-wise sale can provide future sale data in comparison with lifespan which gives future pollutant approximation. Waste compact fluorescent lamps units projected for the year 2015 is 9,300,000,000 units and can emit nearly 9,300 kg of mercury. On the other hand, CRT monitors have been continuously replaced by more improved versions like liquid crystal display and plasma display panel resulting in the production of more waste. Worldwide CRT production was 83,300,000 units in 2002 and can approximately release 83,000 metric tons of lead. © 2013 Springer-Verlag Berlin Heidelberg.

Verma S.,Central University of Himachal Pradesh | Bhardwaj S.,Central University of Himachal Pradesh
Nuclear Physics B | Year: 2016

After the observation of non-zero θ13 the goal has shifted to observe CP violation in the leptonic sector. Neutrino oscillation experiments can, directly, probe the Dirac CP phases. Alternatively, one can measure CP violation in the leptonic sector using Leptonic Unitarity Quadrangle (LUQ). The existence of Standard Model (SM) gauge singlets – sterile neutrinos – will provide additional sources of CP violation. We investigate the connection between neutrino survival probability and rephasing invariants of the 4×4 neutrino mixing matrix. In general, LUQ contain eight geometrical parameters out of which five are independent. We obtain CP asymmetry (Pνf→νf′−Pν¯f→ν¯f′) in terms of these independent parameters of the LUQ and search for the possibilities of extracting information on these independent geometrical parameters in short baseline (SBL) and long baseline (LBL) experiments, thus, looking for constructing LUQ and possible measurement of CP violation. We find that it is not possible to construct LUQ using data from LBL experiments because CP asymmetry is sensitive to only three of the five independent parameters of LUQ. However, for SBL experiments, CP asymmetry is found to be sensitive to all five independent parameters making it possible to construct LUQ and measure CP violation. © 2016 The Authors

Chatterjee A.,Central University of Himachal Pradesh
Pramana - Journal of Physics | Year: 2016

In completely local settings, we establish that a dynamically evolving spherically sym- metric black hole horizon can be assigned a Hawking temperature and with the emission of flux, radius of the horizon shrinks. © Indian Academy of Sciences.

Pant D.,Central University of Himachal Pradesh
International Journal of Environment and Waste Management | Year: 2014

E-waste now has been a rapidly growing problem in terms of quantity and toxicity of its components. Recycling of e-waste becomes rather complicated because of the technological advancement in the materials and composition of the e-equipment. From the management perspective e-waste components can be divided in two categories: 1) organic part contains thermo and thermosetting plastic; 2) inorganic parts consists of metallic and non-metallic components. The current review addresses the various environmental issues related to existing management and proposes microbial participation as a viable and eco-friendly technique. Microbial participation improves the process in a greener way and this technology can be applied for the treatment of both organic as well as inorganic part of the e-waste. It affects organic part principally by its dehalogenation and inorganic part by metal xtraction pattern. © 2014 Inderscience Enterprises Ltd.

Pant D.,Central University of Himachal Pradesh
Process Safety and Environmental Protection | Year: 2016

Recycling method of polycarbonate (PC) plastic using glycerol is proposed as a novel green method. Glycerol was found as an efficient reagent for chemical recycling of PC and gives upto 98% monomer recovery, which is compatible with any of existing chemical recycling methods. Recycling involves digestion followed by glycerolysis reaction of PC. The various products thus obtained are Bisphenol A (BPA); mono glycerol ether of BPA and di glycerol ether of BPA. Addition of urea improves the yield toward more alkoxylated products, controls the dehydration of glycerol to acrolein at reaction temperature and improves the application of glycerol as a reagent. Temperature programmed FTIR spectra study provides a mechanistic picture of the proposed chemical recycling. Glycerol carbonate and glycerol urethane was found as the important reaction intermediates. The process works well with industrial grade glycerol to improve the economy in this process. Furthermore, a working model of the recycling of post-user optical disc is also proposes. © 2016 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.

Verma S.,Central University of Himachal Pradesh
Advances in High Energy Physics | Year: 2015

We present an overview of recent progress in the theoretical and phenomenological studies of neutrino masses, lepton avor mixing, and CP violation. Firstly, We discuss the status of neutrino mass with in the Standard Model (SM) of particle physics. Then the possible ways in which neutrino mass terms can be included in the SM are discussed. The inclusion of new physics beyond the SM inevitably brings new parameters which are not constrained by the present experimental data on neutrino masses and mixing angles and, thus, are free parameters of the theory. We, also, discuss various theoretically motivated phenomenological approaches which can be used to reduce the number of free parameters and, thus, provide an excellent tool to understand the underlying physics of neutrino masses and mixings. Current experimental constraints on the neutrino mass spectrum and the lepton avor mixing parameters, including the recent observation of nonzero θ 13, have been summarized. Finally, We discuss the renewed interest in the possible existence of one or more sterile neutrinos and their phenomenology. © 2015 Surender Verma.

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