Narnaul, India

Central University of Haryana in Jant-Pali village, Mahendragarh district of Haryana, India, which is set up in 500 acres , has been established through an Act of Parliament: "The Central Universities Act, 2009" by the Government of India. The territorial jurisdiction of Central University of Haryana is the whole of the Haryana. The first Convocation of the University was held on March 1, 2014.The university has now shifted at its original campus in Jant Pali, Mahendergarh 11 kilometres from the Mahendergarh on the Mahendergarh-Bhiwani road. Professor U P Sinha is the current acting vice-chancellor of the university. Classes started on August 12, 2013. Construction is still proceeding rapidly. The process of shifting against the agitation of villagers is going on to develop the surrounding area of university.The university has operated from its temporary campus at Government Education College at Narnaul. The university will be named after Lord Krishna.A bus facility is also available from the railway station and bus stand.The Central Universities Bill 2009 aims at creating one new central university each in Bihar, Gujarat, Haryana, Himachal Pradesh, Jammu and Kashmir, Jharkhand, Karnataka, Kerala, Orissa, Punjab, Rajasthan and Tamil Nadu. It also seeks to convert Guru Ghasidas Vishwavidyalaya in Chhattisgarh, Harisingh Gour Vishwavidyalaya in Sagar and Hemwati Nandan Bahuguna Garhwal University in Uttarakhand into Central universities. Wikipedia.


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Kumar S.,University of Central Florida | Kumar S.,Central University of Haryana | Vaidya M.,Mgm Medical College
Molecular and Cellular Biochemistry | Year: 2016

Stem cells have inherent properties of self-renewal and differentiation. High percentage of transplanted stem cells (95 %) die into ischemic heart due to unfavorable environment where in hypoxia considered among major contributing factors. Hypoxia inducible factor-1 α is a well-known transcription factor which robustly induced during hypoxia and an essential factor for adaptation under lower oxygen tension. The effects of hypoxia onto stem cells and its cell cycle are poorly understood. Mesenchymal stem cells were isolated from adult male Fischer-344 rats bone marrow and kept under hypoxia (1 % O2). Cell survival and proliferation were studied using MTT and CFSE assay which showed reduced proliferation rate with an arrest in G0/G1 phase of cell cycle using flow cytometry. Western blot analysis revealed an increase in expressions of HIF-1α along with P53, a tumor suppressor gene. Cyclin-dependent kinase inhibitor (CDKI), p27 was significantly increased, in concordance with the findings, cyclin D1 was also reduced under hypoxia and forestalling S phase entry. In addition, loss of function study with HIF-1α knockdown revealed progression of cell cycle even under hypoxia. Knocking down p27 abrogated the hypoxia-induced G1 checkpoint, suggesting a key regulator of G1/S transition in hypoxic cells. Hypoxia could cause HIF-1α-dependent increase in the expression of p27 leading to cell cycle arrest in G0/G1 phase. The demonstration of the molecular mechanism of hypoxia-induced G1/S regulation provides insight into a fundamental response of stem cells to low oxygen tension. © 2016 Springer Science+Business Media New York


Yadav A.,Central University of Haryana | Garg V.K.,Central University of Punjab
Environmental Science and Pollution Research | Year: 2016

This paper reports the effect of earthworm population density on the vermicomposting of effluent treatment plant sludge of a bakery industry. Four waste mixtures containing 0, 10, 20, and 30 % sludge along with cow dung with five different worm population densities were established for 14 weeks under controlled moisture and temperature conditions. The results showed that average worm biomass, growth and cocoon production were lesser at higher population densities. Sexual maturity was attained in 3rd to 5th week in all waste mixtures. Worm growth was inversely related to worm population density in the waste mixture. Results also indicated that lower worm population is favorable to worm biomass production. On the other hand, mineralization and stabilization of the waste mixtures were more at higher worm populations. © 2016 Springer-Verlag Berlin Heidelberg


Mondal A.,Jawaharlal Nehru Centre for Advanced Scientific Research | Sunda A.P.,Central University of Haryana | Balasubramanian S.,Jawaharlal Nehru Centre for Advanced Scientific Research
Physical Chemistry Chemical Physics | Year: 2016

Critical aspects of thermal behavior and the electrolytic properties of solid-state Protic Organic Ionic Plastic Crystals (POIPCs) are unknown. We present molecular dynamics (MD) simulations on a perfect crystal and a vacancy model to probe such physical phenomena in POIPCs using 1,2,4-triazolium perfluorobutanesulfonate ([TAZ][pfBu]) as an example. The results show the existence of a rotator phase wherein the cations, although translationally ordered are disordered rotationally and exhibit a tumbling motion which significantly affects hydrogen bond lifetimes. van Hove correlation functions characterize the concerted hopping of ions (cation or anion) at 500 K. These results are substantiated by calculated free energy barriers (cation = 2.5 kcal mol-1 and anion = 6 kcal mol-1) and suggest that proton and ion transport influenced by facile hydrogen bond dynamics in the rotator phase contribute to the solid-state conductivity of POIPCs. © 2016 the Owner Societies.


Gupta R.,Central University of Haryana | Mehta G.,University of Delhi | Kuhad R.C.,Central University of Haryana
Journal of Chemical Technology and Biotechnology | Year: 2015

BACKGROUND: The presence of sugar and lignin degradation products, viz. furans and phenolics, make the acid hydrolysate toxic to the microbes. This work attempts to develop an efficient method for the abatement of these microbial inhibitors at pilot scale. RESULT: Among various methods for detoxifying fermentation inhibitors from acid hydrolysate of Prosopis juliflora, activated charcoal (2.0%) removed inhibitors almost completely, followed by ion-exchange resins (73% phenolics and 84% furans). The neutralization and alkalinization treatments removed specifically furans and caused higher loss of sugars (∼50%), while the enzymatic treatment was more effective on removal of furans. The charcoal detoxification process on scale up (20 L), achieved the abatement of 87-93% phenolics and 87-96% furans from acid hydrolysate. The activated charcoal was regenerated and use of regenerated charcoal removed phenolics and furfurals from acid hydrolysate of P. juliflora by 83% and 86%, respectively. The detoxified hydrolysate on fermentation with Pichia stipitis NCIM 3499 produced 6.85 g L-1 ethanol with 0.35 g g-1 yield and 0.43 g L-1 h-1 productivity. CONCLUSION: Activated charcoal adsorption was found to be the most effective and cheap method for abatement of inhibitors. Moreover, regeneration of charcoal and the scalability of the process make it industrially competitive. © 2015 Society of Chemical Industry.


Menon R.S.,Central University of Haryana | Biju A.T.,CSIR - National Chemical Laboratory | Nair V.,Indian National Institute for Interdisciplinary Science and Technology
Beilstein Journal of Organic Chemistry | Year: 2016

N-Heterocyclic carbenes (NHCs) have emerged as a powerful class of organocatalysts that mediate a variety of organic transformations. The Benzoin reaction constitutes one of the earliest known carbon-carbon bond-forming reactions catalysed by NHCs. The rapid growth of NHC catalysis in general has resulted in the development of a variety of benzoin and benzoin-type reactions. An overview of such NHC-catalysed benzoin reactions is presented. © 2016 Menon et al.


Yadav R.P.,Allahabad University | Kumar T.,Central University of Haryana | Mittal A.K.,Allahabad University | Dwivedi S.,Allahabad University | Kanjilal D.,Inter University Accelerator Center
Applied Surface Science | Year: 2015

Si (100) is bombarded with 200keV Ar+ ion beam at oblique incidence with fluences ranging from 3×1017ions/cm2 to 3×1018ions/cm2. The surface morphology of the irradiated surfaces is captured by the atomic force microscopy (AFM) for each ion fluence. The fractal analysis is performed on the AFM images. The autocorrelation function and height-height correlation function are used as fractal measures. It is found that the average roughness, interface width, lateral correlation length as well as roughness exponent increase with ions fluence. The analysis reveals the ripple pattern of the surfaces at higher fluences. The wavelength of the ripple surfaces is computed for each ion fluence. © 2015 Elsevier B.V. All rights reserved.


Saini J.K.,Central University of Haryana | Patel A.K.,Indian Oil Corporation Ltd. | Adsul M.,Indian Oil Corporation Ltd. | Singhania R.R.,Indian Oil Corporation Ltd.
Renewable Energy | Year: 2016

Enzymatic saccharification of biomass is a crucial step in bioethanol production from lignocellulosic biomass through sugar platform which essentially requires attachment of cellulases onto cellulose which is affected by the presence of lignin in biomass. This article focuses on types of interaction between cellulase-lignin and the possible strategies to restrict or overcome it so as to allow maximum cellulases for cellulase-cellulose productive binding. By inhibiting cellulase-lignin binding the cellulase dosage could be reduced dramatically thereby reducing the cost of enzyme in bioethanol process. The techniques to study these interactions have also been discussed. © 2016.


Singh M.,Central University of Haryana | Srivastava R.K.,Central University of Haryana | Srivastava R.K.,Govind Ballabh Pant University of Agriculture & Technology
Environmental Progress and Sustainable Energy | Year: 2016

Constructed wetlands (CW) are well known for removal of organics, suspended solids, nutrients, and bacteria. However, the information on removal of heavy metals and their sequestration in plants especially, the ornamental plants is very limited. In this experimental study, efficiency of horizontal subsurface-flow constructed wetland (HSCW) planted with an ornamental species Polianthus tuberosa L. was evaluated for heavy metal sequestration in the phytomass. The plants were harvested during the peak standing crop in early September, divided into leaves, inflorescence, roots, and rhizomes, and analyzed for six trace elements (Cu, Zn, Ni, Al, Pb, and Fe). Metal concentrations decreased in the order of roots > rhizomes > leaves > inflorescence. The highest concentration in aboveground biomass were recorded for Al (3.66 mg kg-1) and Fe (1.35 mg kg-1), while the lowest concentration was recorded for Pb (0.06 mg kg-1). Belowground biomass also followed the same decreasing trend, the highest concentrations being recorded for Al (6.28 mg kg-1) with 5.78 mg kg-1 and 6.09 mg kg-1 concentration in rhizomes and roots, respectively. The lowest concentration in belowground biomass was recorded for Ni (0.28 mg kg-1) and Pb (0.17 mg kg-1). The belowground/aboveground concentration ratio ranged between 1.19 and 5.13 with an average value of 2.50. Due to average belowground/aboveground biomass ratio < 1, the belowground/aboveground standing stock ratios for all the metals were > 1 except Fe (0.79). The maximum values for bioconcentration factor (BCF) were found for Al and Zn 81.5 and 16.3, respectively. Biological accumulation factor (BAF) and transfer factor (TF) values were > 1 and <1, respectively for most of the heavy metals, which suggests their immobilization in the roots/rhizosphere and therefore, the species can be best suited for phytostabilization. The results of this study therefore provide the comprehensive information on sequestration of Cu, Zn, Ni, Al, Pb, and Fe in vegetation during domestic wastewater treatment in CW with horizontal subsurface flow. © 2015 American Institute of Chemical Engineers Environ Prog.


Kumar M.,Inter University Accelerator Center | Kumar T.,Central University of Haryana | Avasthi D.K.,Inter University Accelerator Center
Scripta Materialia | Year: 2015

Plasmonic properties of metal nanomaterials critically affect on thermal treatments. One of such effects is 'plasmonic-bleaching' observed in 'atom beam co-sputtering' derived Ag:TiO2 nanocomposite thin films, when annealed at 450 °C. The origin of bleaching is investigated using glancing angle X-ray diffraction and Rutherford backscattering spectroscopy. The kinetics of Ag nanoparticles during the deposition and after thermal treatment is presented to understand involved host-matrix interactions. Based on Rutherford Materials Program simulation, possible mechanism of bleaching is presented. © 2015 Acta Materialia Inc. All rights reserved.


Yadav A.C.,Central University of Haryana
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics | Year: 2016

Stochastic processes wherein the size of the state space is changing as a function of time offer models for the emergence of scale-invariant features observed in complex systems. I consider such a sample-space reducing (SSR) stochastic process that results in a random sequence of strictly decreasing integers {x(t)},0≤t≤τ, with boundary conditions x(0)=N and x(τ) = 1. This model is shown to be exactly solvable: PN(τ), the probability that the process survives for time τ is analytically evaluated. In the limit of large N, the asymptotic form of this probability distribution is Gaussian, with mean and variance both varying logarithmically with system size: (τ)∼lnN and στ2∼lnN. Correspondence can be made between survival-time statistics in the SSR process and record statistics of independent and identically distributed random variables. © 2016 American Physical Society.

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