Central Scientific Instruments Organisation CSIO

Chandigarh, India

Central Scientific Instruments Organisation CSIO

Chandigarh, India

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Kumar N.,Central Scientific Instruments Organisation CSIO | Singh D.P.,Central Scientific Instruments Organisation CSIO | Kumar A.,Central Scientific Instruments Organisation CSIO | Sohi B.S.,University Institute of Engineering and Technology
International Journal of Medical Engineering and Informatics | Year: 2010

Measuring the heel strike and toe time during walking provides valuable insight to the spatiotemporal parameters of human gait. The authors developed a sensor mechanism using FSR. Result shows that FSR sensor show high degree of accuracy and repeatability for measuring heel strike and toe contact time. The objective of the research was to develop a rugged and robust sensor mechanism to be used in prosthetic shoes which will help to determine the gait parameters for precise control of intelligent prosthetic devices. © 2010 Inderscience Enterprises Ltd.


Rastogi R.,Central Scientific Instruments Organisation CSIO | Rastogi R.,University of Punjab | Dhindsa N.,Central Scientific Instruments Organisation CSIO | Suri C.R.,Chandigarh Institute of Microbial Technology | And 4 more authors.
Materials Chemistry and Physics | Year: 2012

In nanotechnology, carbon nanotubes are evolving as 'hot spot' due to their applications as most sensitive biosensors. Thus, study of effect of biomolecular interaction is prerequisite for their electrical application in biosensors and bioelectronics. Here, we have explored this effect on electrical properties of carbon nanotubes with DNA as a model biomolecule. A stable conjugate of carbon nanotubes with DNA is formed via covalent methodology employing quantum dot as fluoropore and characterized with various spectroscopic, fluoroscopic and microscopic techniques. CNT-DNA adduct showed decreased transconductance (from 614.46 μS to 1.34 μS) and shift of threshold voltage (from -0.85 V to 2.5 V) due to change in Schottky barriers at metal-nanotube contact. In addition, decrease in hole mobility (from 4.46 × 10 6 to 9.72 × 10 3 cm 2 V -1 s -1) and increase in ON-linear resistance (from 74 k to 0.44 M) conclude large change in device parameters. On the one hand, this substantial change in device parameters after interfacing with biomolecules supports application of carbon nanotubes in the field of biosensors while on the other hand, the same can limit their use in future power electronic devices where stability in device parameters is essential. © 2012 Elsevier B.V. All rights reserved.


Sharma G.,National Institute of Technology Kurukshetra | Kumar S.,Central Scientific Instruments Organisation CSIO | Kumar S.,Academy of Scientific and Innovative Research ACSIR | Kumar A.,National Institute of Technology Kurukshetra | And 8 more authors.
Procedia Computer Science | Year: 2015

Artificial lipid membrane thin films using dip/drop method on gold/carbon printed electrodes have been developed and characterized. Artificial lipid membranes were prepared by using lipid/lipids, Polyvinyl chloride and plasticizers in a defined ratio. Lipid membranes for four basic tastes namely sweetness, sourness, saltiness and bitterness were prepared. The potentiometric response of the membranes was measured for basic tastants such as glucose, hydrogen chloride, sodium chloride, glutamic acid and quinine in different molar concentrations. The response shows the specificity of the membrane for the respective tastants. It has been demonstrated that the lipid membrane can directly be coated on to electrodes and used for electronic tongue applications. © 2015 The Authors.


Rastogi R.,Central Scientific Instruments Organisation CSIO | Tuteja S.,Central Scientific Instruments Organisation CSIO | Tripathi S.K.,University of Punjab | Kaur I.,Central Scientific Instruments Organisation CSIO | Bharadwaj L.M.,Central Scientific Instruments Organisation CSIO
Advanced Science Letters | Year: 2011

Direct electrochemistry of hemoglobin (Hb) is usually implemented by immobilizing it on the electrode. In-situ determination of Hemoglobin is little bit tough due to slow electron transfer in solution phase owing to its complex structure. In this study, we report in-situ direct electrochemistry of hemoglobin using vertically aligned single walled carbon nanotubes (SWNTs) ropes on indium tin oxide (ITO) platform. Morphological characterization of aligned SWNTs is accomplished using optical surface profiler, FE-SEM and AFM. Electrochemical impedance spectroscopy (EIS) of SWNT/ITO electrode reveals reduction in 'charge transfer resistance' for SWNT/ITO electrode in comparison to ITO. Exchange current density increases tenfold (5.4×10 -2 A cm -2) while standard rate constant increases hundred times (1.2×10 -4 C 2s -1cm -2) after vertical alignment of SWNTs on ITO surface. Cyclic voltammetry (CV) of Hb demonstrates tenfold increase in the currents after SWNT immobilization. Kinetic studies using CV revel surface controlled nature of the reaction that is attributed to concentration of Hb molecules in close proximity of the electrode, which in turn is due to negatively charged carboxyl ends of aligned carbon nanotubes. Moreover, a plausible mechanism for increase of peak currents in acidic pH range is also presented that clearly demonstrates the role of oxygen containing groups at the carbon nanotube ends for direct electron transfer from hemoglobin. Sensitivity of the sensor is determined for both lyophilized Hb and that present in red blood cells (RBCs) separated from whole blood. It is found to be 21.2μAμM -1 and 8.94μAdLg -1 respectively. Lower detection limit of hemoglobin is found to be 10 nM. After successful demonstration of aligned carbon nanotubes (CNTs) in solution phase electrochemistry of hemoglobin, SWNT/ITO electrodes can be used for routine clinical determination of hemoglobin in whole blood samples using RBCs. © 2011 American Scientific Publishers.


Kumar N.,Central Scientific Instruments Organisation CSIO | Soni S.,Central Scientific Instruments Organisation CSIO | Kumar A.,Central Scientific Instruments Organisation CSIO | Sohi B.S.,University Institute of Engineering and Technology
Journal of Scientific and Industrial Research | Year: 2010

This study presents design and development of an electronic knee, which uses attached sensors, microcontrollers and electro pneumatic valve arrangement to emulate near natural walk. Being all sensors and mechanical assembly developed indigenously, prototype would be a low cost electronic knee.


Sidhu H.S.,Thapar University | Kumar S.,Central Scientific Instruments Organisation CSIO | Das A.,Central Scientific Instruments Organisation CSIO | Sardana H.K.,Central Scientific Instruments Organisation CSIO
ICIIP 2011 - Proceedings: 2011 International Conference on Image Information Processing | Year: 2011

A novel and efficient stereo matching algorithm based on robust disparity estimation even in the presence of occlusions is presented in this paper. The algorithm employs the Sum of Absolute Difference (SAD) approach for measure of similarity between two images. A pre-processing stage is applied to smoothen the sharp changes in pixel values at the object boundaries and also help in reducing photometric distortion and noise. Occlusions are removed by using Left-Right consistency constraint which will be explained further in this paper. After the calculation of disparity, image information is combined with the pixel disparities to obtain a cleaner disparity map. The developed algorithm was tested on benchmarked Middlebury data sets as well as acquired sample images. The results obtained are in line with the results of the ground truth images. © 2011 IEEE.


Kumar N.,Central Scientific Instruments Organisation CSIO | Sharma G.,Central Scientific Instruments Organisation CSIO | Kumar A.,Central Scientific Instruments Organisation CSIO | Sohi B.S.,Surya World
International Journal of Medical Engineering and Informatics | Year: 2011

The measurements of components of ground reaction force (GRF) are important in biomechanical analysis for clinical gait assessment, gait research, rehabilitation, ergonomics and sports. Ground reaction forces (vertical, fore-aft, lateral) are the reaction forces as a result of contact between the foot and the ground and these forms an integral part of human movement analysis. The purpose of this study was to demonstrate the effects of walking speed on GRF using Kistler quartz force platform embedded on the floor. In order to minimise differences in the gait of normal subjects due to 'constrained' walking, subject were requested to walk with their self-selected walking speed on the walkway. Components of GRF were recorded and analysed using Kistler's Bioware software. It was convincingly observed that with increasing walking speed magnitude of vertical component of ground reaction force increases at F z1 and F z3 whereas decreased at F z2. The for-aft component shows an increasing trend at F y1 and F y2 with increasing walking speed but no such trend can be seen in case of the lateral component. © 2011 Inderscience Enterprises Ltd.

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