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Parfenov A.I.,Central Research Institute of Gastroenterology
Terapevticheskii Arkhiv | Year: 2011

Gluten-sensitive celiac disease (GSCD) belongs to systemic diseases one of manifestations of which may be various hematological disorders. Some patients with GSCD have blood changes, anemia in particular, which precede clinical symptoms of celiac disease. Anemia can arise as a result of disorders in iron, folic acid and/or vitamin B12 absorption. Celiac disease can be associated with thrombocytosis, thrombocytopenia, leucopenia, vein thrombosis, hyposplenism, immunoglobulin A deficiency. Patients with celiac disease have a high risk of lymphoma, especially of T-cell lymphoma associated with enteropathy, B-cell non-Hodgkin's lymphoma. Aglutenic diet, recovery of structure and function of the small intestine eliminate or attenuate hematological disorders associated with GSCD.


Parfenov A.I.,Central Research Institute of Gastroenterology
Terapevticheskii Arkhiv | Year: 2014

Enteropathies (EP) are the common name for pathological (inflammatory, hemorrhagic, erosive-ulcerative, and atrophic) changes in the small bowel. The paper describes the nosological entities of EP and the significance of laboratory and instrumental methods used for their diagnosis. It outlines the principles of etiotropic and pathogenetic therapies.


Belyaeva V.S.,Central Research Institute of Gastroenterology
Terapevticheskii Arkhiv | Year: 2013

S.P. Botkin' works in gastroenterology are indicated. S.P. Botkin did especially many works on acute hepatitis and biliary colic.


Lychkova A.E.,Central Research Institute of Gastroenterology
Bulletin of Experimental Biology and Medicine | Year: 2014

Pacemaker cells of the upper portion of the digestive tract were studied by electromyography of various parts of the stomach and duodenum. Pacemaker cells of the stomach were located mainly at the interface between the lesser curvature and cardia and in the proximal part of the antrum and were characterized by high spontaneous slow-wave and spike activities. Antroduodenal coordination contributes to sequential motor activity of the stomach and duodenum. Pacemaker cells were characterized by a specific shape and a lesser number of myofibrils. © 2014 Springer Science+Business Media New York.


Shcherbakov P.L.,Central Research Institute of Gastroenterology
Terapevticheskii Arkhiv | Year: 2013

The paper deals with new endoscopic imaging techniques for evaluating the mucosa of deep intestinal segments, mainly the small bowel. It shows the history of an enteroscopic method and its technical capabilities. Some pathological conditions for which deep enteroscopic techniques are best suited are characterized.

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