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Viktorov A.A.,Applied Research Center for Medical and Ecological Safety | Gladkikh V.D.,Russian Federal Medical and Biological Agency | Ksenofontov A.I.,National Research Nuclear University MEPhI | Morozova E.E.,Central Childrens Clinical Hospital
Advances in Gerontology | Year: 2015

A method of iterative congruence for searching for the parameters of a kinetic mathematical model for aging of living systems using medical statistics data is developed. Its possibilities for describing risk functions of mortality and life expectancy for humans and animals depending on environmental factors are illustrated. The concept of forecasting environmental risks, i.e., risks to the population’s health from ecological factors, is formulated. © 2015, Pleiades Publishing, Ltd.


Viktorov A.A.,Scientific and Practical Center for Medical and Ecological Safety | Kholodnov V.A.,RAS Institute of Radio Engineering and Electronics | Gladkikh V.D.,Russian Federal Medical and Biological Agency | Alekhnovich A.V.,Central Childrens Clinical Hospital
Advances in Gerontology | Year: 2013

A mathematical model simulating the influence of environment (ENV) on aging of living systems is proposed. The model is based on the concept of continuous adaptation of a biological system (BS) to ENV from the moment of its birth. The adaptation rate as the rate of risk of destruction accumulation is regarded as a competition between two concurrent processes-BS destruction and recombination of damages defined by kinetics of autocatalytic chemical reactions. The effect of ENV is taken into account by model parameters, which in general are time-dependent. The model reflects the rules of thermodynamics and gerontology as well as the typical results of medical experiments. © 2013 Pleiades Publishing, Ltd.

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