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Ramli Y.,British Petroleum | Ramli Y.,Mohammed V University | Moussaif A.,Center National dEtudes Scientifiques et Techniques dEnergie Nucleaire | Zouihri H.,French National Center for Scientific Research | And 2 more authors.
Acta Crystallographica Section E: Structure Reports Online | Year: 2011

In the crystal structure of the title compound, C22H 18N4O, the quinoxaline system makes dihedral angles of 86.59 (7) and 63.37 (9)° with the benzohydrazide and phenyl rings, respectively. The benzohydrazide ring makes a dihedral angle of 72.46 (10)° with the phenyl ring. The crystal structure is stabilized by intermolecular N-H⋯O hydrogen bonds, C-H⋯O contacts and C-H⋯π inter-actions.


Ramli Y.,Mohammed V University | Ramli Y.,Laboratoire National Of Controle Des Medicaments | Moussaif A.,Mohammed V University | Moussaif A.,Center National dEtudes Scientifiques et Techniques dEnergie Nucleaire | And 3 more authors.
Acta Crystallographica Section E: Structure Reports Online | Year: 2010

The asymmetric unit of the title compound, C16H 14N2O, contains three independent mol-ecules. The dihedral angles between the quinoxaline and phenyl planes in the three mol-ecules are 82.58 (8), 85.66 (9) and 85.36 (9)°. The crystal packing is stabilized by C - H⋯O and C - H⋯N hydrogen bonds.


Ramli Y.,British Petroleum | Ramli Y.,Mohammed V University | Zouihri H.,French National Center for Scientific Research | Azougagh M.,British Petroleum | And 2 more authors.
Acta Crystallographica Section E: Structure Reports Online | Year: 2012

The title compound, C 16H 10N 2S, is almost planar (r.m.s. deviation for all non-H atoms = 0.080 Å). The dihedral angle between the three fused-ring system and the phenyl ring is 9.26 (3)°. The S atom and the opposite C atom of the thiophene ring are mutually disordered with an occupancy ratio of 0.7706 (19):0.2294 (19).


Ramli Y.,Laboratoire National Of Controle Des Medicaments | Moussaif A.,Center National dEtudes Scientifiques et Techniques dEnergie Nucleaire | Karrouchi K.,Mohammed V University | Essassi E.M.,Mohammed V University
Journal of Chemistry | Year: 2014

Quinoxalinone and its derivatives are used in organic synthesis for building natural and designed synthetic compounds and they have been frequently utilized as suitable skeletons for the design of biologically active compound. This review covers updated information on the most active quinoxalinone derivatives that have been reported to show considerable pharmacological actions such as antimicrobial, anti-inflammatory, antidiabetic, antiviral, antitumor, and antitubercular activity. It can act as an important tool for chemists to develop newer quinoxalinone derivatives that may prove to be better agents in terms of efficacy and safety. © 2014 Youssef Ramli et al.

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