Center National Dapplication Des Recherches Pharmaceutiques Bp

Antananarivo, Madagascar

Center National Dapplication Des Recherches Pharmaceutiques Bp

Antananarivo, Madagascar
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PubMed | Center National Dapplication Des Recherches Pharmaceutiques Bp
Type: Journal Article | Journal: Organic letters | Year: 2014

The new triterpene turranoic acid (1) and the new N-containing nor-triterpene turraenine (2), along with triptocallic acid B (3) and esculentoic acid (4) were isolated from leaves of a Turraea sp. Compounds 1-3 showed weak to moderate in vitro antiplasmodial activity against the chloroquine-resistant Plasmodium falciparum strain FCM29. Compound 1 also displayed weak cytotoxic activity against the nonsmall lung cancer cell line H522-T1 with an IC50 value of 16.4 M.

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