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Karou S.D.,University of Lome | Sanou D.,University of Ouagadougou | Pignatelli S.,Center Medical Saint Camille Of Ouagadougou | Pietra V.,Center Medical Saint Camille Of Ouagadougou
Asian Pacific Journal of Tropical Medicine | Year: 2011

Objective: To assess the prevalence of parasitic infections among patients attending Saint Camille Medical Centre and to estimate co-parasitic infections rates. Methods: From January to December 2009, stool samples were collected from 11 728 persons, aged from five months to 72 years and suffering from gastroenteritis. After macroscopic description, the stools were examined by light microscopy to search for the presence of parasites. Results: From the 11 728 analyzed stools, 6 154 (52.47%) were infected with at least one parasite. Protozoan frequently encountered were: Giardia intestinalis (43.47%), Entamoeba histolytica/Entamoeba dispar (30.74%) and Trichomonas intestinalis (21.72%), while Hymenolepis nana (2.25%) was the most common helminth. Co-infections occurred in 22.34% cases. Within the multi-infected samples, dual and triple infections accounted for 71.18% and 20.00%, respectively. Giardia intestinalis for protozoan and Hymenolepis nana for helminths were the most implicated co-infections. Conclusions: This study confirms that intestinal parasites are still a public health problem in Burkina Faso. To reduce the incidence of parasitic infections, it is necessary to promote the education of people so that they practice the rules of individual and collective hygiene. © 2011 Hainan Medical College. Source

Bayala B.,University of Ouagadougou | Bayala B.,University Blaise Pascal | Bayala B.,French National Center for Scientific Research | Bayala B.,French Institute of Health and Medical Research | And 15 more authors.
PLoS ONE | Year: 2014

This research highlights the chemical composition, antioxidant, anti-inflammatory and anti-proliferative activities of essential oils from leaves of Ocimum basilicum, Ocimum americanum, Hyptis spicigera, Lippia multiflora, Ageratum conyzoides, Eucalyptus camaldulensis and Zingiber officinale. Essential oils were analyzed by gas chromatography-mass spectrometry and gas chromatography-flame ionization detector. Major constituents were α-terpineol (59.78%) and β-caryophyllene (10.54%) for Ocimum basilicum; 1, 8-cineol (31.22%), camphor (12.730%), α-pinene (6.87%) and trans α-bergamotene (5.32%) for Ocimum americanum; β-caryophyllene (21%), α-pinene (20.11%), sabinene (10.26%), β-pinene (9.22%) and α-phellandrene (7.03%) for Hyptis spicigera; p-cymene (25.27%), β-caryophyllene (12.70%), thymol (11.88), γ-terpinene (9.17%) and thymyle acetate (7.64%) for Lippia multiflora; precocene (82.10%)for Ageratum conyzoides; eucalyptol (59.55%), α-pinene (9.17%) and limonene (8.76%) for Eucalyptus camaldulensis; arcurcumene (16.67%), camphene (12.70%), zingiberene (8.40%), β-bisabolene (7.83%) and β-sesquiphellandrène (5.34%) for Zingiber officinale. Antioxidant activities were examined using 1,1-diphenyl-2-picryl-hydrazyl (DPPH) and 2,2′-azinobis-(3- ethylbenzothiazoline-6-sulfonic acid (ABTS) methods. O. basilicum and L. multiflora exhibited the highest antioxidant activity in DPPH and ABTS tests, respectively. Anti-inflammatory properties were evaluated by measuring the inhibition of lipoxygenase activity and essential oil of Z. officinale was the most active. Anti-proliferative effect was assayed by the measurement of MTT on LNCaP and PC-3 prostate cancer cell lines, and SF-763 and SF-767 glioblastoma cell lines. Essential oils from A. conyzoides and L. multiflora were the most active on LNCaP and PC-3 cell lines, respectively. The SF-767 glioblastoma cell line was the most sensitive to O. basilicum and L. multiflora EOs while essential oil of A. conyzoides showed the highest activity on SF-763 cells. Altogether these results justify the use of these plants in traditional medicine in Burkina Faso and open a new field of investigation in the characterization of the molecules involved in anti-proliferative processes. © 2014 Bayala et al. Source

Karou S.D.,University of Lome | Kabre A.,Center Medical Saint Camille Of Ouagadougou | Anani K.,University of Lome | Pietra V.,Center Medical Saint Camille Of Ouagadougou | And 2 more authors.
Asian Pacific Journal of Tropical Biomedicine | Year: 2012

Objective: To assess the prevalence of bacterial strains and fungal strains infecting the vaginaltract and test their sensitivity to antibiotics in women attending Saint Camille Medical Centre in Ouagadougou. Methods: From January 2008 to December 2009, a total of 2 000 vaginal swabs were cultivated for bacterial and fungal identification and isolation. Furthermore, bacterialstrains were tested for their susceptibility to several antibiotics used in routine in the centre.Results: The results revealed that microbial isolation and identification was attempted for 1536/2 000 sample, a positivity rate of 76.80%. Candida albicans (48.76%), followed by Escherichia coli (16.67%), Streptococcus agalactiae (8.14%) and Staphylococcus aureus (7.55%) were the major agents of genital tract infections in patients. Mycoplasma hominis and Ureaplasma urealyticum combined accounted for less than 7%. Trichomonas vaginalis was identified in 1.04% cases. The antimicrobial tests revealed that the microorganisms developed resistance to several antibioticsincluding beta lactams. However, antibiotics such as cefamenzol, ciprofloxacin and norfloxacinwere still active on these bacteria. Conclusions: The results reveal that many sexually activewomen are infected by one or more microbial pathogens, probably because of the lack of hygieneor the adoption of some risky behaviors, such as not using condoms or having multiple sexualpartners. Efforts should be made to address these points in the country. Source

Douamba Z.,Center Medical Saint Camille Of Ouagadougou | Douamba Z.,University of Ouagadougou | Martinetto M.,Center Medical Saint Camille Of Ouagadougou | Pietra V.,Center Medical Saint Camille Of Ouagadougou | And 7 more authors.
Journal of Nutrition and Metabolism | Year: 2012

The New Misola consists of millet soybean, peanut, vitamins, minerals, and industrial amylase. Our objective is to demonstrate that porridge made from local grains and legumes restores the nutritional balance of malnourished children. The study was carried on 304 malnourished children aged 6-48 months including 172 girls and 132 boys from Saint Camille Medical Centre. At the beginning, these malnourished children had a WHZ z-score of -3.10 and a WAZ z-score of -3.85, which reflected, according to WHO, a severe malnutrition. After eight weeks of nutritional rehabilitation, a normal WHZ of -1.41 was obtained. These children recovered more than those in a similar study performed in 2006 with the old formula of Misola. This study shows that malnutrition remains a public health problem in Burkina Faso. It should be necessary that public health services and the epidemiologists work in synergy with nutritionists and "nutrigenetics" in order to combat malnutrition efficiently. © 2012 Zoenabo Douamba et al. Source

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