Nouakchott, Mauritania
Nouakchott, Mauritania

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Lekweiry K.M.,University of Nouakchott | Lekweiry K.M.,Cadi Ayyad University | Basco L.K.,Institute Of Recherche Biomedicale Des Armees | Basco L.K.,Institut Universitaire de France | And 14 more authors.
Transactions of the Royal Society of Tropical Medicine and Hygiene | Year: 2011

Although malaria has become a serious public health problem in Mauritania since the late 1990s, few documented data on its epidemiology exist. The objective of this study was to assess the morbidity of clinical malaria among children in Nouakchott.Three hundred and one febrile children, consulting at three health facilities of Nouakchott, were screened for malaria in 2009 (n= 216) and 2010 (n= 85). Plasmodium species identification and parasite density were determined by microscopic examination of Giemsa-stained thin and thick films and confirmed by rapid diagnostic test and nested PCR. Of 301 febrile children, 105 (34.9%) were malaria-positive by nested PCR and 87 (28.9%) by microscopy. Plasmodium vivax represented 97.1% (102/105) and P. falciparum accounted for 2.9% (3/105) of positive cases. All positive children under five years old were infected with P. vivax. The highest numbers of malaria positives were found during or shortly after the rainy season and the lowest during the dry season. Fifty-four of 105 (51.4%) malaria cases, all with P. vivax, had never travelled outside Nouakchott. Individuals belonging to the Moors ethnic group represented 97.0% of P. vivax cases. Results of the present study indicate that malaria is endemic in Nouakchott and that P. vivax is the principal causative agent. Regular surveillance is required to monitor malaria prevalence and incidence, and further measures are needed to counter the possible spread of malaria in the country. © 2011 Royal Society of Tropical Medicine and Hygiene.


Veten F.M.,Faculte des science et Techniques | Abdelhamid I.O.,Center Hospitalier National | Meiloud G.M.,Faculte des science et Techniques | Ghaber S.M.,Center Hospitalier National | And 3 more authors.
Hemoglobin | Year: 2012

Of 1050 Mauritanian blood donors screened from the two main racial groups, i.e., the Moors and Black Africans, 60 were found to carry Hb S [β6(A3)Glu→Val, GAG>GTG], giving a global frequency of 5.71. The prevalence observed in the Black African Mauritanians (10.69) is almost five times that found in the Moor group (2.25). Four of the five main βS haplotypes were detected in this study: Senegal (77.8), Benin (8.8), Arab-Indian (5.5) and Bantu (4.4). These data showed that Hb S is a serious public health problem in Mauritania. They also confirm the ethnic heterogeneity of the Mauritanian population. © 2012 Informa Healthcare USA, Inc.


Hamed C.T.,Sanguine | Bollahi M.A.,Sanguine | Abdelhamid I.,Center Hospitalier National | Med Mahmoud M.A.,ISET de Rosso | And 4 more authors.
International Journal of Immunogenetics | Year: 2012

There is no data available on the ABO/Rh(D) frequencies in the Mauritanian population. We retrospectively analysed records of a 5-year database that contained ABO/Rh phenotype and ethnic origin of 10116 volunteers giving blood at the national blood transfusion centre to derive the frequencies of ABO/Rh(D) groups in the Mauritanian population. The two race categories in the country and their sub-ethnic groups: the Moors (whites and black) and the black Africans (Pulhars, Soninkes and Wolof) were included in this study. Globally, group O had the highest frequency (49.10%) followed by A (28.28%), B (18.56%) and AB (4.05%). This order more common in North African populations was found in four of the five ethnic groups composing our population. Allele frequencies were, respectively, 70.20%, 17.74% and 12.04% giving the same order of O>A>B. We observed no significant variation in these frequencies between the different ethnic groups. Rhesus study showed that with a percentage of 94.23% Rh(D) positive is by far the most prevalent, while Rh(D) negative is present only in 5.77% of the total population. This frequency distribution supports the mixed-race composition of the Mauritanian population. © 2011 Blackwell Publishing Ltd.


Abdelhamid I.,Center Hospitalier National | Lasram K.,Institute Pasteur Of Tunis | Meiloud G.,British Petroleum | Ben Halim N.,Institute Pasteur Of Tunis | And 4 more authors.
Primary Care Diabetes | Year: 2014

Aims Many genetic association studies reported the contribution of KCNJ11 gene to type 2 diabetes susceptibility in different populations. We aimed to evaluate the association between E23K variant of KCNJ11 and type 2 diabetes in the Mauritanian population. Materials and methods We performed a case-control association study including 135 type 2 diabetes Mauritanian patients and 135 controls. Genotyping for the E23K variant was performed using a TaqMan allelic discrimination assay. Results We found significant association between KCNJ11 E23K variant and type 2 diabetes (Global model, OR = 2.08, 95% CI = 1.09-3.97, p = 0.026). In the Moor ethnic group, E23K was also associated with type 2 diabetes in the general model (OR = 2.08, 95% CI = 1.09-3.97, p = 0.026) and under the dominant model (OR = 2.49, 95% CI = 1.12-5.55, p = 0.026). In the Mauritanians of African descent, KK genotype was not found. Besides, E23K variant was not associated with type 2 diabetes (OR = 0.69, 95% CI = 0.04-11.32, p = 0.793). Conclusions Our results revealed the risk of type 2 diabetes conferred by KCNJ11 E23K gene variant in the Mauritanian population. © 2013 Primary Care Diabetes Europe.


PubMed | British Petroleum, UCAD, Center Hospitalier National and Institute Pasteur Of Tunis
Type: Journal Article | Journal: Primary care diabetes | Year: 2014

Many genetic association studies reported the contribution of KCNJ11 gene to type 2 diabetes susceptibility in different populations. We aimed to evaluate the association between E23K variant of KCNJ11 and type 2 diabetes in the Mauritanian population.We performed a case-control association study including 135 type 2 diabetes Mauritanian patients and 135 controls. Genotyping for the E23K variant was performed using a TaqMan allelic discrimination assay.We found significant association between KCNJ11 E23K variant and type 2 diabetes (Global model, OR=2.08, 95% CI=1.09-3.97, p=0.026). In the Moor ethnic group, E23K was also associated with type 2 diabetes in the general model (OR=2.08, 95% CI=1.09-3.97, p=0.026) and under the dominant model (OR=2.49, 95% CI=1.12-5.55, p=0.026). In the Mauritanians of African descent, KK genotype was not found. Besides, E23K variant was not associated with type 2 diabetes (OR=0.69, 95% CI=0.04-11.32, p=0.793).Our results revealed the risk of type 2 diabetes conferred by KCNJ11 E23K gene variant in the Mauritanian population.


Diagana M.S.,Center Hospitalier National | Kane H.,Center Norbert Elias | Kane H.,Societe Francaise de Sante Publique
Sante Publique | Year: 2016

The World Health Organization recommends exclusive breastfeeding up to the age of six months and continuation of partial breastfeeding up to the age of two years, in addition to nutritionally adequate and safe food. In Mauritania, despite some progress, most mothers do not comply with these recommendations. The aim of this study, conducted in Nouakchott, was to evaluate breastfeeding and feeding practices, and measure factors associated with achievement of the optimal duration of exclusive breastfeeding. The methodology combined quantitative and qualitative approaches. A descriptive cross-sectional study was conducted by questionnaires among 330 mothers from different departments of the capital. Twenty semi-structured interviews were then conducted with Mauritanian grandmothers in order to understand their roles and perceptions about infant feeding. Before the age of 6 months, the exclusive breastfeeding rate was 18.4%, the predominant breastfeeding rate was 44.3% and the partial breastfeeding with milk rate was 28.1%. In addition, 9.2% of infants received supplementary feeding. We found that 50.5% of mothers were aware of the optimal duration of exclusive breastfeeding, but only 14.2% complied with this recommendation. The factors significantly associated with compliance with the optimal duration of exclusive breastfeeding were maternal age over 35 years and multiparity. Interviews revealed that grandmothers knew about some of the nutritional recommendations, but denied their relevance based on their experience. Their advice contradicted certain medical recommendations. Our study revealed inadequacies concerning the mother's knowledge and more frequently their practices in terms of infant feeding. The gap between knowledge and practice can be essentially explained by the relative importance attributed to recommendations by the mothers, as well as the confrontation between medical recommendations and grandmothers' traditional knowledge.


Sidatt M.,Center hospitalier national | Ould Sidi Mohamed Wedih A.,Center hospitalier national | Ould Boubaccar A.,Service de radiologie | Ould Ely Litime A.,Center El Mourabitoune Of Chirurgie Pediatrique | And 2 more authors.
Archives de Pediatrie | Year: 2013

Hydrocolpos and the hydrometrocolpos are anomalies resulting from vaginal and uterine retention and accumulation of cervicovaginal secretions caused by congenital malformation. It is a rare pathology affecting the female newborn and infant and much less often young girls. It appears clinically as an abdominal mass associated with absence or abnormality of the vaginal opening. The diagnosis is confirmed by abdominal echography and CT scan. Treatment varies from the simple X-shaped hymenotomy for the isolated imperforate hymen to major surgery for substantial retentions and complex urogenital abnormalities. The authors report two cases of hydrocolpos and hydrometrocolpos discovered in the neonatal period. These were two newborn babies resulting from poorly followed pregnancies at which the clinical examination noted in both cases a large abdominal mass. The physical examination, imagery and surgical exploration demonstrated the existence of enormous hydrocolpos with imperforate hymen in 1 case and hydrometrocolpos with distal vaginal atresia in the second case. The treatment consisted of draining the secretions for both patients, after an X-shaped hymenotomy for the first and after section anastomosis of the vaginal atresia for the second. Both cases progressed favorably. © 2012 Elsevier Masson SAS.


PubMed | Center hospitalier des specialites and Center hospitalier national
Type: Journal Article | Journal: Neuro-Chirurgie | Year: 2016

We describe the case of a 41 year-old woman who presented with a slight slowness of the right hand movement, which began four months prior to admission. Neurological examination showed slight rest tremor of the right hand, moderate bradykinesia and rigidity. She had been taking medication for Parkinsons disease, but without any benefit. The patient underwent a gadolinium-enhanced brain MRI, which showed a large left sphenoid wing meningioma with surrounding edema compressing the basal ganglia. Total excision of tumor was performed. The right hemiparkinsonian signs were completely resolved. This rare case underlines the significance of neuroimaging in patients presenting with Parkinsons disease especially in those patients with a relatively younger age at onset or unresponsive to medication.


Congenital nasolacrimal duct obstruction is a frequent pathology in ophthalmologic consultation. Spontaneous cure is frequent in the first six months. Between the age of six months and one year, simple nasolacrimal duct probing resolves the epiphora in 90% of cases. After the age of one, surgical intervention under general anaesthetic is proposed. The use of nasal endoscopy allows treatment to be conducted under visual control, which was not possible with earlier techniques (silicone intubation or balloon catheter dilatation). Endoscopic access allows the cause of the epiphora to be determined and treated. In a third of cases, the cause revealed by endoscopy is a simple membranous nasolacrimal duct obstruction. In another third, the cause is a pseudo-cystic dilation of the nasal ostium (valve of Hasner). In the final third, an anomaly in the size and diameter of the membranous nasolacrimal duct, sometimes associated with abnormal connection to the inferior turbinate and permeability of the lacrimal passage, is identified. Endoscopic treatment allows two essential curative measures to be taken: luxation of the inferior turbinate and opening of the valve of Hasner. Silicone intubation is no longer necessary. Avoiding the use of silicone intubation frees the patient from any postoperative follow-up.


PubMed | Center hospitalier national
Type: Case Reports | Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie | Year: 2013

Hydrocolpos and the hydrometrocolpos are anomalies resulting from vaginal and uterine retention and accumulation of cervicovaginal secretions caused by congenital malformation. It is a rare pathology affecting the female newborn and infant and much less often young girls. It appears clinically as an abdominal mass associated with absence or abnormality of the vaginal opening. The diagnosis is confirmed by abdominal echography and CT scan. Treatment varies from the simple X-shaped hymenotomy for the isolated imperforate hymen to major surgery for substantial retentions and complex urogenital abnormalities. The authors report two cases of hydrocolpos and hydrometrocolpos discovered in the neonatal period. These were two newborn babies resulting from poorly followed pregnancies at which the clinical examination noted in both cases a large abdominal mass. The physical examination, imagery and surgical exploration demonstrated the existence of enormous hydrocolpos with imperforate hymen in 1 case and hydrometrocolpos with distal vaginal atresia in the second case. The treatment consisted of draining the secretions for both patients, after an X-shaped hymenotomy for the first and after section anastomosis of the vaginal atresia for the second. Both cases progressed favorably.

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