Time filter

Source Type

Brahmi S.A.,Center Hospitalier Mohammed | Zahra Z.F.,Center Hospitalier Hassan | Seddik Y.,Center Hospitalier Mohammed | Afqir S.,Center Hospitalier Mohammed
Pan African Medical Journal | Year: 2016

Cancer is a major public health problem in Africa. The progress in cancer treatment over the past decade is undeniable. The emergence of targeted therapies in oncology made it possible to modify the natural history of some cancers associated with a poor prognosis. Despite their efficiency, these therapies pose a major health care problem that makes them inaccessible to most patients in developing countries. In Morocco, cancer is considered a long-term condition and for this reasons patients have health insurance coverage. The involvement of civil society made it possible even to improve therapy management as well as a broader poor patient’s access to innovative medicines. © Sami Aziz Brahmi et al.


Tali A.,Center hospitalier Mohammed | Addebbous A.,Center hospitalier Mohammed | Asmama S.,Center hospitalier Mohammed | Chabaa L.,Center hospitalier Mohammed | Zougaghi L.,Center hospitalier Mohammed
Annales de Biologie Clinique | Year: 2011

Respiratory cryptosporidiosis is recognized as a late-stage complication in persons with AIDS.We report two cases of respiratory cryptosporidiosis in patients with HIV infection. The first patient was a 46-year-old person with chronic diarrhea, a two-month history of low-grade fever, progressive dyspnea and productive cough. The search for acid-fast bacillus, Pneumocystis jirovecii, Toxoplasma gondii and Cryptococcus sp. in sputum was negative on several samples. The modified Ziehl has shown oocysts of Cryptosporidium sp. in induced sputum. The patient's death occurred, due to electrolytes disorders. The second patient was a 45-year-old person hospitalized for chronic fluid diarrhea, complicated with weight loss, dry cough, dyspnea stage II and low-grade fever. The patient was HIV-positive with low CD4 count and pancytopenia. Acid-fast oocysts of Cryptosporidium sp. were observed in stool samples and induced sputum. The patient was treated daily with azithromycin 500 mg resulting of disappearance of gastrointestinal and respiratory disorders.


Bouchbika Z.,Hassan II University | Haddad H.,Hassan II University | Benchakroun N.,Hassan II University | Eddakaoui H.,Hassan II University | And 5 more authors.
Pan African Medical Journal | Year: 2013

Introduction: Few population-based cancer registries are in place in developing countries. In order to know the burden of cancer in Moroccan population, cancer registry initiative was put in place in the Casablanca district, the biggest city of Morocco. Methods: The data collected covers 3.6 millions inhabitant and included Casablanca city and the administrative region. Results: The data collected in the years 2005-07 show that the top 5 forms of cancers in women were breast (ASR: 36.4 per 100,000), cervical (15.0), thyroid (6.7), colon-rectum (5.8), and ovarian (5.3); the top 5 cancers in men were lung (25.9), prostate (13.5), bladder (8.7), colon-rectum (8.1) and non-Hodgkin lymphoma (7.2). Tumours of haematopoietic and lymphoid tissues represented 11% of all cancers (skin excluded); some presented unusual sex ratios. For breast, cervical, colorectal and thyroid cancer, respectively 57%, 42%, 28% and 60% of the cases were under 50 years of age. This was attributable to particularly low numbers of cases recorded among old people, and the young age of the general population; the observed age-specific incidences under age 50 were not higher than in western countries. Cancers at young ages were particularly common in women: 67% of the cases were under 50. Stage at diagnosis could be obtained for 82% of the breast cancer cases and was as follows: 28% local, 63% regional and 9% distant, in the absence of screening. Conclusion: These first population-based data have provided an invaluable resource for the national cancer control plan of Morocco, and will be useful tool to its future evaluation. © Zineb Bouchbika et al.


PubMed | Center Hospitalier Mohammed
Type: Case Reports | Journal: Annales de biologie clinique | Year: 2011

Respiratory cryptosporidiosis is recognized as a late-stage complication in persons with AIDS. We report two cases of respiratory cryptosporidiosis in patients with HIV infection. The first patient was a 46-year-old person with chronic diarrhea, a two-month history of low-grade fever, progressive dyspnea and productive cough. The search for acid-fast bacillus, Pneumocystis jirovecii, Toxoplasma gondii and Cryptococcus sp. in sputum was negative on several samples. The modified Ziehl has shown oocysts of Cryptosporidium sp. in induced sputum. The patients death occurred, due to electrolytes disorders. The second patient was a 45-year-old person hospitalized for chronic fluid diarrhea, complicated with weight loss, dry cough, dyspnea stage II and low-grade fever. The patient was HIV-positive with low CD4 count and pancytopenia. Acid-fast oocysts of Cryptosporidium sp. were observed in stool samples and induced sputum. The patient was treated daily with azithromycin 500 mg resulting of disappearance of gastrointestinal and respiratory disorders.


PubMed | Hassan II University, Center Hospitalier Mohammed, Institute of Tropical Medicine and Regional Directorate of Health of Casablanca
Type: | Journal: The Pan African medical journal | Year: 2014

Few population-based cancer registries are in place in developing countries. In order to know the burden of cancer in Moroccan population, cancer registry initiative was put in place in the Casablanca district, the biggest city of Morocco.The data collected covers 3.6 millions inhabitant and included Casablanca city and the administrative region.The data collected in the years 2005-07 show that the top 5 forms of cancers in women were breast (ASR: 36.4 per 100,000), cervical (15.0), thyroid (6.7), colon-rectum (5.8), and ovarian (5.3); the top 5 cancers in men were lung (25.9), prostate (13.5), bladder (8.7), colon-rectum (8.1) and non-Hodgkin lymphoma (7.2). Tumours of haematopoietic and lymphoid tissues represented 11% of all cancers (skin excluded); some presented unusual sex ratios. For breast, cervical, colorectal and thyroid cancer, respectively 57%, 42%, 28% and 60% of the cases were under 50 years of age. This was attributable to particularly low numbers of cases recorded among old people, and the young age of the general population; the observed age-specific incidences under age 50 were not higher than in western countries. Cancers at young ages were particularly common in women: 67% of the cases were under 50. Stage at diagnosis could be obtained for 82% of the breast cancer cases and was as follows: 28% local, 63% regional and 9% distant, in the absence of screening.These first population-based data have provided an invaluable resource for the national cancer control plan of Morocco, and will be useful tool to its future evaluation.


PubMed | Center Hospitalier Mohammed and Center Hospitalier
Type: | Journal: The Pan African medical journal | Year: 2016

Docetaxel is a chemotherapeutic agent belonging to the taxane family. This drug is widely used to treat cancers. Interstitial lung disease is a rare but serious toxicity due to the high mortality risk. We report a case of a patient with breast cancer who had fatal acute interstitial lung disease after auxiliary chemotherapy with docetaxel. The clinician should be aware of this risk and should consider it in differential diagnosis in patients with respiratory symptoms treated with docetaxel.


PubMed | Center Hospitalier Mohammed and Center Hospitalier Hassan
Type: | Journal: The Pan African medical journal | Year: 2016

Cancer is a major public health problem in Africa. The progress in cancer treatment over the past decade is undeniable. The emergence of targeted therapies in oncology made it possible to modify the natural history of some cancers associated with a poor prognosis. Despite their efficiency, these therapies pose a major health care problem that makes them inaccessible to most patients in developing countries. In Morocco, cancer is considered a long-term condition and for this reasons patients have health insurance coverage. The involvement of civil society made it possible even to improve therapy management as well as a broader poor patients access to innovative medicines.


PubMed | Center Hospitalier Mohammed and Center Hospitalier Hassan
Type: | Journal: The Pan African medical journal | Year: 2016

Breast cancer is one of the most common cancers in premenopausal women and its treatment may affect their fertility. Indeed, chemotherapy used in breast cancer may cause transient or permanent amenorrhea in premenopausal women.We conducted a retrospective study of young patients with localized breast canceri in the Department of Medical Oncology, Mohammed VI Inuversity Hospital, Oujda, Morocco over a 3-year period from January 2009 to December 2011. The aim of our study was to analyse the impact of chemotherapy-induced amenorrhea (CIA) as well as predictive factors for its occurrence.In our series, 74% of patients had CIA and 33.6% of patients had definitive chemotherapy-induced amenorrhea. Several factors have been studied in search of predictive factors for amenorrhea occurrence. With regard to the age factor, our analysis showed that women over 40 were more likely to have amenorrhea than those aged less than 40 years (95.7% versus 56.1%), with a statistically significant difference (p = 0.003).In our study the incidence of ICA seems comparable to that found in the literature, while age is the predominant predictor of its occurrence.

Loading Center Hospitalier Mohammed collaborators
Loading Center Hospitalier Mohammed collaborators