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Herin F.,Nancy University Hospital Center | Poussel M.,Nancy University Hospital Center | Renaudin J.-M.,Center Hospitalier Jean Monnet | Leininger A.,Nancy University Hospital Center | And 3 more authors.
International Journal of Tuberculosis and Lung Disease | Year: 2012

The present case study reports the first case of a 38-yearold hairdresser with irritant-associated vocal cord dysfunction (VCD) due to alkaline persulfate, who was referred on suspicion of occupational asthma. Several tests were performed, including specific inhalation challenge and upper airway endoscopy. During the specific inhalation challenge to alkaline persulfate, the patient experienced dysphonia and a non-significant decrease in forced expiratory volume in 1 second on spirometry. Upper airway endoscopy was then performed and revealed VCD. A specific inhalation challenge test is therefore essential in cases of VCD to exclude possible concomitant occupational asthma. © 2012 The Union.

We are discussing the clinical case of a patient with fibromyalgia syndrome as well as her treatment during a consultation intended to evaluate her chronic pain. Initially, this generalised pain disorder is dealt with in a multidisciplinary way by each professional of the team in order to understand the disorder from a different angle. The different dimensions of pain, i.e., somatic, psychological and social can be better understood as well as the manner in which they are related to each other in the general history of a chronic pain disorder. The evaluation explains the different dimensions of pain, more precisely and effectively, and proposes different strategies for the treatment of chronic pain disorder. As was highlighted in the patient's file, there could be a relation between a very specific phobia and chronic pain syndrome. After evaluating the file, it was then decided to focus on realistic objectives in agreement with the patient after a more detailed psychometric evaluation. Cognitive and behavioural therapy treatment is integrated in a therapeutic plan including medication with the pursuit of physical therapy and planned rehabilitation. In addition, there is the option of complementary techniques such as relaxation and hypnotherapy. © 2010 Elsevier Masson SAS. All rights reserved.

Exercise-induced anaphylaxis is defined as the onset of allergic symptoms during, or immediately after exercise, the clinical signs being various degrees of urticaria, angioedema, respiratory and gastrointestinal signs, and sometimes anaphylactic shock. Food-dependent exercise-induced anaphylaxis (FDEIA) introduces food as a factor in the syndrome and follows a particular chronological sequence: food intake is followed, after a variable interval, by exercise, during the course of which the clinical signs of FDEIA appear. When the food intake and the exercise are independent of each other, no symptoms occur. FDEIA occurs infrequently. Identification of the responsible food depends on the patient's eating habits. Seafood and wheat flour are the two commonest causes. Once the allergen has been identified, it should not be eaten for at least four to five hours before any exercise. © 2010 Elsevier Masson SAS. All rights reserved.

Renaudin J.-M.,Center Hospitalier Jean Monnet
Revue Francaise d'Allergologie | Year: 2010

Insect stings may cause anaphylactic reactions at the workplace or during working hours. Epidemiologic studies of Hymenoptera venom hypersensitivity specifically of occupational origin or of asthma induced by stinging insects are limited. There are few reports on the occupational outcome of these allergies. © 2010 Elsevier Masson SAS. All rights reserved.

Lupi R.,University of Tuscia | Lupi R.,French National Institute for Agricultural Research | Masci S.,University of Tuscia | Rogniaux H.,French National Institute for Agricultural Research | And 6 more authors.
Journal of Cereal Science | Year: 2014

Breeding has enabled the development of wheat genotypes with different quality characteristics and end uses. Despite its numerous positive properties that make it one of the most cultivated crops, wheat is known to induce allergic reactions in predisposed consumers. Genetic modification (GM) technology for crop improvement has recently emerged and its impact on allergenicity must be evaluated, as recommended by the Codex Alimentarius. Our aim was to determine whether the variation in the amount of allergenic polypeptides in five GM wheats, along with their untransformed genotypes, was equivalent to the variation observed among twenty commercial cultivars, either durum or bread wheats. Since the most important factor involved is the amount of allergenic polypeptides, we performed Enzyme-Linked Immunoabsorbent Assays with IgE from twenty-two patients suffering from food or respiratory allergy to wheat on two well characterised soluble protein fractions. Statistical analyses showed a significant effect of the genotypes and sera, both by considering GM lines and untransformed genotypes. This study leads us to conclude that a wide variation exists in the amount of allergenic polypeptides among durum and bread wheat cultivars, and that the differences observed between GM wheats and their parents are within the range of cultivated wheats. © 2014 Elsevier Ltd.

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