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Armony-Sivan R.,Center For Human Growth And Developmentuniversity Of Michigan300 galls | Clark K.M.,Center For Human Growth And Developmentuniversity Of Michigan300 galls | Richards B.,Center For Human Growth And Developmentuniversity Of Michigan300 galls | Kaciroti N.,Center For Human Growth And Developmentuniversity Of Michigan300 galls | Lozoff B.,Center For Human Growth And Developmentuniversity Of Michigan300 galls
Developmental Psychobiology | Year: 2015

This study considered effects of timing and duration of iron deficiency (ID) on frontal EEG asymmetry in infancy. In healthy term Chinese infants, EEG was recorded at 9 months in three experimental conditions: baseline, peek-a-boo, and stranger approach. Eighty infants provided data for all conditions. Prenatal ID was defined as low cord ferritin or high ZPP/H. Postnatal ID was defined as ≥ two abnormal iron measures at 9 months. Study groups were pre- and postnatal ID, prenatal ID only, postnatal ID only, and not ID. GLM repeated measure analysis showed a main effect for iron group. The pre- and postnatal ID group had negative asymmetry scores, reflecting right frontal EEG asymmetry (mean±SE: -.18±.07) versus prenatal ID only (.00±.04), postnatal ID only (.03±.04), and not ID (.02±.04). Thus, ID at both birth and 9 months was associated with right frontal EEG asymmetry, a neural correlate of behavioral withdrawal and negative emotions. © 2015 Wiley Periodicals, Inc.

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