Chen S.-S.,National Central University |
Chuang Y.-W.,National Central University |
Chen P.-Y.,National Central University |
Chen P.-Y.,Center for General Education
Knowledge-Based Systems | Year: 2012
Firms can obtain competitive advantages from their employees' knowledge sharing behaviors. This paper presents a research model to examine the direct and indirect effects of knowledge management systems (KMS) quality, KMS self-efficacy, organizational climate and attitude on the intention to share knowledge in the new product development process. The hypotheses are tested on data collected from 134 major electronic manufacturing firms in Taiwan, using partial least squares regression. The results of the empirical study suggest that attitude is the key factor influencing intention to engage in knowledge sharing. The more a factor (such as KMS self-efficacy and organizational climate) positively contributes to attitude, the more the factor contributes to knowledge sharing. The findings provide useful insights into how organizations should encourage employees' collaborative behaviors or activities so as to reinforce KMS self-efficacy create a favorable organizational climate that will in turn enhance attitude and intention to engage in knowledge sharing leading to benefits for the organization as a whole. © 2012 Elsevier Ltd. All rights reserved.
Wen S.-Y.,Taipei Medical University Hospital |
Wen S.-Y.,Center for General Education |
Liu W.-L.,Taipei Medical University Hospital |
Liu W.-L.,National Taipei University of Nursing and Health Sciences
Pediatrics | Year: 2015
BACKGROUND: There are limited population-based data regarding pediatric herpes zoster (HZ). abstract METHODS: Children aged < 12 years with varicella infections between 2000 and 2006 were identified from a national population-based database and followed-up for a diagnosis of HZ until December 2008. Since a routine varicella vaccination program was started in 2004, vaccinated children without medically attended varicella were identified between 2004 and 2006, and followed-up for a diagnosis of HZ until December 2008. RESULTS: Of 27 517 children with medically attended varicella, 428 developed HZ. The incidence of HZ was 262.1 per 100 000 person-years. Of 25 132 vaccinated children without medically attended varicella, 106 developed HZ. The incidence of HZ was 93.3 per 100 000 person-years. The mean duration from varicella to HZ was 4.12 years. Children diagnosed with varicella at aged ,< 2 years had a higher incidence (P , < .001) and shorter duration (P = .04) than those diagnosed aged ≥ 2 years. Children diagnosed with varicella aged ≥ 2 but < 8 years had a significantly increased incidence of HZ after than before the vaccination program (relative risk = 1.85 at 3 years of follow-up, P = .03). Children with varicella infections had a significantly greater risk of HZ than vaccinated children without a history of varicella (relative risk = 2.31 at 4 years of follow-up, P ,< .001). CONCLUSIONS: This study demonstrates the population-based epidemiologic characteristics of pediatric HZ among those who contracted varicella. In the early postvaricella vaccination period, an increased HZ incidence was observed among children with varicella infection aged ≥2 years. Copyright © 2015 by the American Academy of Pediatrics.
Yang M.-S.,Chung Yuan Christian University |
Tian Y.-C.,Chung Yuan Christian University |
Tian Y.-C.,Center for General Education
Information Sciences | Year: 2015
Fuzzy clustering is generally an extension of hard clustering and it is based on fuzzy membership partitions. In fuzzy clustering, the fuzzy c-means (FCM) algorithm is the most commonly used clustering method. Numerous studies have presented various generalizations of the FCM algorithm. However, the FCM algorithm and its generalizations are usually affected by initializations. In this paper, we propose a bias-correction term with an updating equation to adjust the effects of initializations on fuzzy clustering algorithms. We first propose the so-called bias-correction fuzzy clustering of the generalized FCM algorithm. We then construct the bias-correction FCM, bias-correction Gustafson and Kessel clustering and bias-correction inter-cluster separation algorithms. We compared the proposed bias-correction fuzzy clustering algorithms with other fuzzy clustering algorithms by using numerical examples. We also applied the bias-correction fuzzy clustering algorithms to real data sets. The results indicated the superiority and effectiveness of the proposed bias-correction fuzzy clustering methods. © 2015 Elsevier Inc.
Yu W.-W.,Kaohsiung Veterans General Hospital |
Hsieh P.-P.,Kaohsiung Veterans General Hospital |
Hsieh P.-P.,Center for General Education |
Chuang S.-S.,Chi Mei Medical Center |
Chuang S.-S.,Taipei Medical University
Journal of Cutaneous Pathology | Year: 2013
Primary cutaneous γδ T-cell lymphoma and extranodal natural killer (NK)/T-cell lymphoma (ENKTL), nasal type are two distinct lymphoma entities in the World Health Organization (WHO) classification. We report the case of an aggressive cutaneous lymphoma of γδ T-cell origin showing overlapping features of both lymphomas. A 78-year-old female presented with confluent erythematous plaques with ulcerations over her right thigh. Microscopically, section of the skin showed a diffuse dermal and subcutaneous lymphocytic infiltration with tumor necrosis and angioinvasion. The medium- to large-sized tumor cells expressed CD3, CD8, cytotoxic molecules and T-cell receptor (TCR)-? but not CD4, CD20, CD30, CD56 or ßF1. In situ hybridization for Epstein-Barr virus-encoded mRNA (EBER) was diffusely positive. Polymerase chain reaction-based clonality assay showed a clonal TCR-γ chain gene rearrangement. The features compatible with γδ T-cell lymphoma include dermal and subcutaneous involvements, cytotoxic phenotype, expression of TCR-γ, as well as an aggressive course. On the other hand, the diffuse EBER positivity, angioinvasion, tumor necrosis and cytotoxic phenotype may also fit in the diagnosis of an ENKTL of T-cell lineage. We review the literature on EBER-positive γδ T-cell lymphoma and discuss the diagnostic dilemma using the current WHO classification system. Copyright © 2012 John Wiley & Sons A/S.
Lai S.-L.,Center for General Education |
Chen H.-J.H.,National Taiwan Normal University
Computer Assisted Language Learning | Year: 2015
A number of studies have suggested the possible benefits of using concordancers in English as a Foreign Language (EFL) writing. To date, however, there is still limited understanding of how EFL writers may make use of such tools along with dictionaries when engaging in a writing task. To better understand the question, this study investigated a class of non-English-major college students (N = 14) over a semester. Four online corpus tools, including monolingual and bilingual concordancers and collocation retrieval systems, were provided, along with two online dictionaries. After two tool-training sessions, students performed three timed-writing tasks online during three consecutive months and received individual stimulus recall interviews after each writing task. The recall interviews served as the main source of data; other data included the video clips of the writing process, student writing samples, and the researchers’ notes. The result showed that students used corpus tools and the bilingual dictionary for different purposes. They tended to use a bilingual dictionary when information on word form and word meaning was needed. When searching for information related to word usage, collocation information, and grammar patterns, they chose corpus tools more often than a bilingual dictionary. However, they also turned to corpus tools for meaning and form when the bilingual dictionary failed to provide clear word meanings, when they needed to search for word strings, and when they needed to just confirm an intuition regarding either word form or word meaning. This study provides empirical data that help to better understand how corpus tools contribute to EFL writing. © 2013 Taylor & Francis.
Chen H.-T.,China Medical University at Taichung |
Chen H.-T.,Feng Chia University |
Tsou H.-K.,Feng Chia University |
Tsou H.-K.,Taichung Veterans General Hospital |
And 3 more authors.
PLoS ONE | Year: 2012
Background: Hepatocyte growth factor (HGF) has been demonstrated to stimulate osteoblast proliferation and participated bone remodeling. Osteopontin (OPN) is a secreted phosphoglycoprotein that belongs to the SIBLING family and is present during bone mineralization. However, the effects of HGF on OPN expression in human osteoblasts are large unknown. Methodology/Principal Findings: Here we found that HGF induced OPN expression in human osteoblasts dose-dependently. HGF-mediated OPN production was attenuated by c-Met inhibitor and siRNA. Pretreatment of osteoblasts with PI3K inhibitor (Ly294002), Akt inhibitor, c-Src inhibitor (PP2), or AP-1 inhibitor (curcumin) blocked the potentiating action of HGF. Stimulation of osteoblasts with HGF enhanced PI3K, Akt, and c-Src activation. In addition, incubation of cells with HGF also increased c-Jun phosphorylation, AP-1-luciferase activity, and c-Jun binding to the AP-1 element on the OPN promoter. HGF-mediated AP-1-luciferase activity and c-Jun binding to the AP-1 element was reduced by c-Met inhibitor, Ly294002, Akt inhibitor, and PP2. Conclusions/Significance: Our results suggest that the interaction between HGF and c-Met increases OPN expression in human osteoblasts via the PI3K, Akt, c-Src, c-Jun, and AP-1 signaling pathway. © 2012 Chen et al.
Lai L.-W.,Center for General Education
International Journal of Environmental Health Research | Year: 2014
The aim of the study is to assess the relationship between PM2.5, synoptic weather patterns, and admissions for circulatory and respiratory disease. A PM2.5 event is defined as a day when the daily mean PM2.5 concentration exceeds 65g/m3. PM2.5 events that coincided with the occurrence of PM attributed to Asian dust storm (ADS) and photochemical smog (PCS) were removed from the study in order to focus solely on the health effects from PM2.5. A one-tailed z-test and a relative risk (RR) estimate were performed. Hospital admissions for respiratory diseases were greater than those for circulatory diseases, and asthma-related diseases had a higher impact in the Adults group, and the maximum RR was 1.94 [1.37 2.77] on the first day after the event. It is evident that PM2.5 episodes connected to particular synoptic weather patterns pose a risk to health as large as ADS and PCS events. © 2013 © 2013 Taylor & Francis.
Lai L.-W.,Center for General Education
International Journal of Environmental Health Research | Year: 2012
This study focuses on the relationship between photochemical smog (PS) (hourly ozone conc. >100 ppb), PS-related diseases, and the synoptic weather patterns during 2005-2009 in metropolitan Taipei. The results show that compared to respiratory ailments (ICD code 460-519) and asthma (ICD code 493), cardiovascular ailments (ICD code 390-459) were more clearly influenced by PS events. On the PS event day, the number of admissions of babies, children, and adults increased by 0.04 [95% CI 0.01-0.06], 0.03 [95% CI 0.00-0.07], and 1.12 [95% CI 0.36-1.89] (P < 0.05), respectively. The investigation showed that more than 70% of the PS events were associated primarily with the peripheral circulation of typhoons, Pacific pressure, and discrete Pacific pressure. PS events are a threat to public health. To avoid the ill effects of air pollution, residents should be informed about the daily weather patterns and air quality. © 2012 Copyright Taylor and Francis Group, LLC.
Lou J.H.,Center for General Education
The journal of nursing research : JNR | Year: 2010
Further understanding the relationship between sexual cognition and sexual communication in adolescents may facilitate sexual health promotion in this population. This study was designed to investigate associations between sexual cognitive variables and sexual communication in adolescents. This study used a cross-sectional research design with conventional sampling. Data were collected from one medical college in central Taiwan. A total of 900 questionnaires were dispatched, with 748 copies returned, giving a response rate of 83.1%. Structural questionnaires were designed to collect demographic data, sexual self-concept inventory, sexual risk cognition, sexual self-efficacy, and sexual communication scale. This study applied statistical methods, including descriptive statistics, Pearson product-moment correlation, and multiple regression analysis. Major findings revealed that (a) adolescents talked about sexual activity and sexual issues with their parents at a moderate level (mean = 2.52, SD = 1.24), (b) all sexual cognitive variables (sexual self-concept, sexual risk cognitions, and sexual self-efficacy) correlated positively with sexual communication, and (c) predictors of sexual communication were supported by demographic data (having heterosexual friends, satisfaction with heterosexual friends, and duration of relationships with heterosexual friends) and sexual cognitive variables, which accounted for 62.0% of variance. CONCLUSIONS/IMPLICATIONS FOR PRACTICE: Study results can contribute to the development of safe sexual health programs and improve healthcare provider knowledge of sexual communication among adolescents. More sexual communication between adolescents and their parents is encouraged. Moreover, sexual health programs must give increased focus on the issue of adolescent sexual cognition to help encourage increased discussion between adolescents and their parents regarding sexual activity and issues.
Lai L.-W.,Center for General Education
International Journal of Environmental Health Research | Year: 2011
The objective of this study was to clarify the associations between dengue vectors and the number of dengue fever admissions. We statistically analyzed the daily meteorological and sea surface temperature (SST) data obtained from 13 monitoring stations for 2002-2007, the daily number of dengue fever admissions to hospitals, as well as the Breteau index (BI) values obtained from the Taiwan Centres for Disease Control for the 38 political districts of metropolitan Kaohsiung. It was found that hot and wet environmental conditions were caused by warm SSTs together with the weather patterns that cause typhoons and high-pressure areas in the tropical Pacific Ocean. The conditions clearly contribute to an increase in the BI. Synoptic weather patterns still remain an important factor in determining the growth of dengue vectors, particularly in rural areas, although public health programs and improved environmental sanitation can also reduce the threat of the disease. © 2011 Taylor &Francis.