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Demaison X.,Center Medical Des Armees Of Clermont Ferrand | Rapp C.,Service de Pathologie Infectieuse et Tropicale | de Laval F.,Center Depidemiologie Et Of Sante Publique Des Armees | Simon F.,Service de Pathologie Infectieuse et Tropicale
Medecine et Maladies Infectieuses

Context.-Non-falciparum malaria is less studied than Plasmodium falciparum malaria, both in endemic and non-endemic zones. Patients and method: A retrospective study was made of the medical files of patients managed for attacks of malaria due to Plasmodium vivax or Plasmodium ovale, between 2000 and 2009, in two French military teaching hospitals. Results: Seventy-five percent of attacks occurred after a stay in French Guiana, in the Comoros Archipelago, or in the Ivory Coast Republic. The most frequent symptoms two months after coming back were a flu-like syndrome with headaches, and occasional digestive symptoms, without any difference between the first attack and recurrence. One third of patients presented with anemia, 78% with thrombocytopenia, and 12% with liver dysfunction. Discussion: This study was the most important made in France on imported non-falciparum malaria. Military patients and immigrants accounted for a majority of patients due to the specificity of military hospitals and local recruitment. Clinical and biological features were not specific and did not allow guiding the diagnosis. Diagnostic tools were less sensitive for P. ovale. Conclusion: Patient management could be optimized by more efficient diagnostic tools, specific guidelines for the diagnostic and therapeutic management, and a dedicated medical training for family practitioners as well as hospitals practice. © 2013. Source

Tanti M.,Center Depidemiologie Et Of Sante Publique Des Armees
2014 4th International Symposium ISKO-Maghreb: Concepts and Tools for Knowledge Management, ISKO-Maghreb 2014

In science, the document has never been defined, much less analyzed, including upheavals trained its transition to electronic and web 2.0. It is this analysis that offers head to this article based on the RTP DOC theory that defines the document as both medium container and contents. In our proposal, seen as a medium, the scientific paper is defined as the message vector among scientists. It is designed as a competition object that requires recognition of peer competitors. Seen as containing, it is a stable logical and physical structure, regardless of the subject area and built in parts and sub-parts in order to direct his presentation. Finally, as content, we define the scientific paper published as written, validated by experts, which describes the original search results. © 2014 IEEE. Source

Tanti M.,Center Depidemiologie Et Of Sante Publique Des Armees
2013 3rd International Symposium ISKO-Maghreb

Documents are ubiquitous in everyday life. For example, the textbook serves to know the alphabet and the technical brochure serves to know how to ride a piece of furniture. However, the process to acquire such knowledge from the document has never been modeled. That is what this article proposes to do by a systemic modeling. In the pyramid model developed, the document is the base of the pyramid. It carries data (alphabetic signs⋯). These data, once interpreted by humans, transmit information. This information, when they are organized, structured and 'contextualized' become knowing. This knowing, combined with other knowing acquired for example in the context of education, when they are applied, to answer the situation in a global context of reflection, become knowledge. This knowledge will allow, for example, to take a decision or action and in turn will be the basis for another pyramid also modeled. © 2013 IEEE. Source

Migliani R.,Ecole du Val de Grace | Pradines B.,Institute Of Recherche Biomedicale Des Armees | Pradines B.,Aix - Marseille University | Michel R.,Center Depidemiologie Et Of Sante Publique Des Armees | And 5 more authors.
Travel Medicine and Infectious Disease

Each year, 40,000 French soldiers deploy or travel through malaria-endemic areas. Despite the effective control measures that were successively implemented, malaria remains a public health concern in French armed forces with several important outbreaks and one lethal case every two years. This article describes the malaria control strategy in French armed forces which is based on three combined strategies: i) Anopheles vector control to prevent infection with the implementation of personal protection against vectors (PPAV) adapted to the field living conditions of the troops. ii) Chemoprophylaxis (CP) to prevent the disease based on prescription of effective and well tolerated doxycycline. iii) Management of cases through early diagnosis and appropriate treatment to prevent death. In isolated conditions in endemic areas, rapid diagnosis tests (RDT) are used as first-line tests by military doctors. Treatment of uncomplicated Plasmodium falciparum (P. falciparum) malaria is based either on the piperaquine tetraphosphate-dihydroartemisinin association since 2013, or on the atovaquone-proguanil association. First-line treatment of severe P. falciparum malaria is based on IV artesunate. These measures are associated with constant education of the military, epidemiological surveillance of malaria cases and monitoring of parasite chemosensitivity. © 2013 Elsevier Ltd. All rights reserved. Source

Matheus S.,Institute Pasteur Of La Guyane | Pham T.B.,Far East Medical Vietnam Ltd | Labeau B.,Institute Pasteur Of La Guyane | Huong V.T.Q.,Institute Pasteur Vietnam | And 3 more authors.
American Journal of Tropical Medicine and Hygiene

Large-scale epidemiological surveillance of dengue in the field and dengue patient management require simple methods for sample collection, storage, and transportation as well as effective diagnostic tools. We evaluated the kinetics of three biological markers of dengue infection - non-structural protein 1 (NS1) antigen, immunoglobulin M (IgM), and IgA - in sequential capillary blood samples collected from fingertips of confirmed dengue patients. The overall sensitivities and specificities of the tests were 96% and 100%, respectively, for NS1, 58.1% and 100%, respectively, for IgM, and 33% and 100%, respectively, for IgA. During the acute phase of the disease, NS1 was the best marker of dengue infection, with a sensitivity of 98.7%, whereas from day 5, all three markers exhibited relevant levels of sensitivity. This first descriptive study of the kinetics of biological markers of dengue in capillary blood samples confirms the usefulness of this biological compartment for dengue diagnosis and argues for its exploitation in community-level and remote settings. Copyright © 2014 by The American Society of Tropical Medicine and Hygiene. Source

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