Entity

Time filter

Source Type

Los Angeles, CA, United States

Patent
Cedars Sinai Medical Center | Date: 2015-04-17

Described herein are gene signatures providing prognostic, diagnostic, treatment and molecular subtype classifications of ovarian cancers through generation of ovarian cancer disease signatures (OCDSs) that account for molecular heterogeneity present in gynecological cancers. An ovarian cancer fixed signature (OCFS) is described which relates to the core programming of disease development, in addition to an ovarian cancer stem cell (OCSC) signature. Development various disease signature, suggests personalized treatment strategies focused on molecular subtypes of gynecological cancers, such as triage tests for patients.


Patent
Cedars Sinai Medical Center | Date: 2015-02-09

The invention relates to the use of enzymes, nanorods, and nanoelectronic devices to detect cysteine level in a patient sample and relates to the use of the detected cysteine level to predict cancer recurrence in the patient and to prescribe and/or administer an appropriate therapy to a subject. The invention is directed to systems and methods of detecting cysteine level in a sample from a subject, wherein the systems or methods can further comprise measuring at least one additional parameter, such as PSA level, Gleason score and clinical stage. The invention is directed to systems and methods of predicting the probability of a recurrence of a cancer in a subject, wherein the systems or methods can further comprise measuring at least one additional parameter, such as PSA level, Gleason score and clinical stage. The invention further comprises prescribing and/or administering an appropriate therapy to a subject based on the predicted probability of recurrence.


Described herein are methods and systems for distinguishing irritable bowel syndrome (IBS) from inflammatory bowel disease (IBD) and celiac disease. The methods and systems can utilize the detection of anti-vinculin antibodies and anti-CdtB antibodies to distinguish IBS from IBD and celiac disease. Further described are methods for selecting a therapy to treat IBS, IBD or celiac disease.


The present invention teaches systems and methods for a simple cardiac MRI approach that (1) continuously acquires data; (2) covers the entire heart with high isotropic resolution within a few minutes; and (3) requires no physiological gating and minimal user intervention. Applications of the inventive systems and methods include, but are in no way limited to cardiac cine, myocardial perfusion, coronary MRA, delayed enhancement imaging, myocardial T1-weighted imaging for fibrosis imaging, and myocardial T2-weighted imaging for edema imaging.


Patent
Cedars Sinai Medical Center | Date: 2015-08-26

The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers found in women that are at risk for preterm delivery.

Discover hidden collaborations