Cebu Doctors' University is a private university located in Mandaue City, Cebu, Philippines. It was founded in 1975 at Cebu City, as Cebu Doctors' College, with the opening of its College of Nursing, one of the first nursing colleges in Cebu Wikipedia.
Pabalan N.A.,Angeles University Foundation |
Pabalan N.A.,Cebu Doctors University |
Pabalan N.A.,University of Saint Louis |
Seim I.,The Innovation Group |
And 4 more authors.
BMC Genetics | Year: 2014
Background: There is growing evidence that the ghrelin axis, including ghrelin (GHRL) and its receptor, the growth hormone secretagogue receptor (GHSR), play a role in cancer progression. Ghrelin gene and ghrelin receptor gene polymorphisms have been reported to have a range of effects in cancer, from increased risk, to protection from cancer, or having no association. In this study we aimed to clarify the role of ghrelin and ghrelin receptor polymorphisms in cancer by performing a meta-analysis of published case-control studies. We conducted searches of the literature published up to January 2013 in MEDLINE using the PubMed search engine. Individual data on 8,430 cases and 14,008 controls from six case-control studies of an all Caucasian population were evaluated for three ghrelin gene (GHRL; rs696217, rs4684677, rs2075356) and one ghrelin receptor (GHSR; rs572169) polymorphism in breast cancer, esophageal cancer, colorectal cancer and non-Hodgkins lymphoma. Results: In the overall analysis, homozygous and recessive associations indicated that the minor alleles of rs696217 and rs2075356 GHRL polymorphisms conferred reduced cancer risk (odds ratio [OR] 0.61-0.78). The risk was unchanged for breast cancer patients when analysed separately (OR 0.73-0.83). In contrast, the rs4684677 GHRL and the rs572169 GHSR polymorphisms conferred increased breast cancer risk (OR 1.97-1.98, p = 0.08 and OR 1.42-1.43, p = 0.08, respectively). All dominant and co-dominant effects showed null effects (OR 0.96-1.05), except for the rs572169 co-dominant effect, with borderline increased risk (OR 1.08, p = 0.05). Conclusions: This study suggests that the rs696217 and rs2075356 ghrelin gene (GHRL) polymorphisms may protect carriers against breast cancer, and the rs4684677 GHRL and rs572169 GHSR polymorphisms may increase the risk among carriers. In addition, larger studies are required to confirm these findings.
Galarpe R.K.R.,Mindanao University of Science and Technology |
Galarpe R.K.R.,Xavier University - Ateneo de Cagayan |
Parilla R.,Cebu Doctors University
Journal of Environmental Science and Management | Year: 2014
Selected heavy metals in leachate and groundwater in Cebu City Sanitary Landfill (CCSL), Philippines were studied. Levels of Pb, Cd, Cr, and Cu in total form were determined by Flame- AAS and Hg by cold vapor AAS. Study commenced on April, May, August, and October of 2010 covering wet and dry seasons. Studied leachate stations exceeded the standards for Pb (0.1968 mg L-1) and Hg (0.14838 mg L-1) with risk quotient (RQ) values >1. Groundwater stations exceeded the standard for Pb (0.0371 mg L-1) and Cd (0.0042 mg L-1) with RQ >1. It can be inferred that the groundwater adjacent to CCSL was slightly impacted by leachate metal constituents. Therefore, it is recommended that further monitoring would be carried out and the leachate would be contained to protect the groundwater prior to CCSL closure.
Tsai Y.-T.,Chang Gung University |
Cala-Or Ma.A.C.,Cebu Doctors University |
Lui C.-C.,Chang Gung University |
Wang T.-J.,Chang Gung University |
Lai J.-P.,Chang Gung University
Cleft Palate-Craniofacial Journal | Year: 2013
We report a female infant with presentation of epignathus teratoma involving duplication of both the mandible and tongue. Epignathus with duplication of the mandible has rarely been reported in the literature thus far. The location and extent of the tumor, as well as the involvement of adjacent structures, resulted in trismus and upper airway obstruction at birth. Thus, staged operations including debulking and correction of anatomical anomaly were performed on this patient after life-saving tracheostomy. As a result, we not only prevented morbidity associated with the anomaly but also refined the patient's appearance and improved her quality of life. © Copyright 2013 American Cleft Palate-Craniofacial Association.
Tan G.H.,Cebu Doctors University
Annals of Global Health | Year: 2015
Background Diabetes is increasing at an alarming rate in Asian countries including the Philippines. Both the prevalence and incidence of type 2 diabetes (T2D) continue to increase with a commensurate upward trend in the prevalence of prediabetes. Objectives The aim of this study was to review the prevalence of diabetes in the Philippines and to describe extensively the characteristics of diabetes care in the Philippines from availability of diagnostics tests to the procurement of medications. Methods A literature search was performed using the search words diabetes care and Philippines. Articles that were retrieved were reviewed for relevance and then synthesized to highlight key features. Findings The prevalence of diabetes in the Philippines is increasing. Rapid urbanization with increasing dependence on electronic gadgets and sedentary lifestyle contribute significantly to this epidemic. Diabetes care in the Philippines is disadvantaged and challenged with respect to resources, government support, and economics. The national insurance system does not cover comprehensive diabetes care in a preventive model and private insurance companies only offer limited diabetes coverage. Thus, most patients rely on "out-of-pocket" expenses, namely, laboratory procedures and daily medications. Consequently, poor pharmacotherapy adherence impairs prevention of complications. Moreover, behavioral modifications are difficult due to cultural preferences for a traditional diet of refined sugar, including white rice and bread. Conclusions Translating clinical data into practice in the Philippines will require fundamental and transformative changes that increase diabetes awareness, emphasize lifestyle change while respecting cultural preferences, and promote public policy especially regarding the health insurance system to improve overall diabetes care and outcomes. © 2015 The Author. Published by Elsevier Inc.
Zubiri J.S.,Cebu Doctors University |
Zubiri J.S.,Vicente Sotto Memorial Medical Center
Aesthetic Surgery Journal | Year: 2013
Increasing numbers of Asian patients of varying ethnicity are expressing preferences and expectations for a specific aesthetic appearance following double eyelid surgery. Those of Northern Mongolian ethnicity (Northern Chinese, Japanese, or Korean heritage) generally prefer a narrow crease, whereas those of Southern Mongolian ethnicity (Indonesian, Filipino, or Malaysian) prefer a wider fold. Older techniques performed until the mid-1990s resulted in a deep fold, giving the patients a more "Western" appearance. In this article, the author describes a modified technique of placing the suture in the subdermal layer, which allows for variety in the width of the fold, enabling the surgeon to retain anatomical aspects that are typical of each patient's ethnicity. With this technique, an Asian patient may now choose the width of fold that he or she prefers, resulting in a more ethnically natural look. © 2013 The American Society for Aesthetic Plastic Surgery, Inc.