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de Goede M.,University of Amsterdam | Leander A.,Cbs Therapeutics, Inc. | Sullivan G.,University of Kent
Environment and Planning D: Society and Space | Year: 2016

This articles introduces the special issue on ‘The Politics of the List.’ We observe that lists proliferate as a technique of governance across multiple domains, including health, security, and commerce. We argue that it is important to take seriously the form and technique of the list itself and engage the knowledge practices, governance effects and ways of ordering the world that the list format enables. In other words, the special issue seeks to ‘remain in the register of the list,’ to unpack its technological arrangements and juridical power. This introduction sets out the key themes of this special issue, through discussing, in turn, the list as a technology of knowledge, the list as a technique of law and governance, the list's complex relation to space and the relation between the list and the digital. We draw on these four elements to characterise what we call the politics of the list in an era of complexity. © 2016, © The Author(s) 2016. Source

Leander A.,Cbs Therapeutics, Inc.
Environment and Planning D: Society and Space | Year: 2016

This article looks closely at the politics of whitelists in commercial security. It argues that whitelists are essential for the current transformations in regulatory politics in which Codes of Conduct, Best Practices, Benchmarks and Standards are replacing more conventional, legally binding forms of regulation. The article traces how whitelists are tied to these transformations. The account is organized around how the practical, pragmatic and poetic character of lists (Umberto Eco) fashion the work and topological imprint (Manuel DeLanda) of whitelists in commercial security specifically. The article directs attention to the politics of the work and topological imprint of whitelists. This politics is neither hidden nor invisible yet it remains largely unnoted. It is dispersed, mundane and unspectacular. The whitelists are akin to minions whose activities are turning softly regulated commercial security into an infernal alternative (imagery borrowed from Pignarre and Stengers). As minions, whitelists appear insignificant when looked at in isolation. However, by describing their work as a decentralized, disjointed and disorganized group, this article shows their significance for the politics of regulation in commercial security. It advances a conceptualization of this politics and a theorization of its dynamics of relevance for engaging the politics of lists also elsewhere. © 2015, © The Author(s) 2015. Source

Rombouts J.V.K.,France Business School | Stentoft L.,Cbs Therapeutics, Inc.
Computational Statistics and Data Analysis | Year: 2014

Option pricing using mixed normal heteroscedasticity models is considered. It is explained how to perform inference and price options in a Bayesian framework. The approach allows to easily compute risk neutral predictive price densities which take into account parameter uncertainty. In an application to the S&P 500 index, classical and Bayesian inference is performed on the mixture model using the available return data. Comparing the ML estimates and posterior moments small differences are found. When pricing a rich sample of options on the index, both methods yield similar pricing errors measured in dollar and implied standard deviation losses, and it turns out that the impact of parameter uncertainty is minor. Therefore, when it comes to option pricing where large amounts of data are available, the choice of the inference method is unimportant. The results are robust to different specifications of the variance dynamics but show however that there might be scope for using Bayesian methods when considerably less data is available for inference. © 2013 Elsevier B.V. All rights reserved. Source

Harbers M.M.,National Institute for Public Health and the Environment | Verschuuren M.,National Institute for Public Health and the Environment | De Bruin A.,Cbs Therapeutics, Inc.
Archives of Public Health | Year: 2015

Background: The European Commission, together with the European Union (EU) Member States, developed a core set of indicators for monitoring public health in the EU, the European Core Health Indicators (ECHI) shortlist. From 2009 to 2012 developmental work on the ECHI indicators continued within the framework of the Joint Action for European Community Health Indicators and Monitoring (ECHIM). In this article, we give the current state of affairs on the availability of data for the ECHI indicators in the Netherlands and show what progress has been made over the past 5 years. The information provided serves as an illustration of the challenges encountered in a European country when working on harmonising national data collections with international data delivery requirements.Methods: To assess data availability, we consulted Dutch data experts and relevant websites and reports on health monitoring activities. We compared the available Dutch data with the definitions, preferred data sources and relevant dimensions as requested by ECHI.Results: The Netherlands can provide data for 66 of the 75 ECHI indicators for which availability could be assessed: for all of the 48 ECHI indicators that can be extracted from international databases and for 18 of the 27 indicators not available from international databases. Breakdowns by socio-economic status and region are not possible for 23 (35%) of the total of 66 indicators for which data are available and for 21 (32%) of these 66 indicators the definition is not exactly the same as requested by ECHIM. Since 2009, better estimates have become available for low birth weight, practising physicians and practising nurses.Moreover, several European initiatives to improve harmonised data collection are expected to have a positive effect on data availability for the Netherlands. Such initiatives should become sustainable in order to provide possibilities for monitoring trends. The scattered data ownership in the Netherlands complicates the coordination work for international data deliveries.Conclusion: Data availability in the Netherlands is good. Since 2009, several Dutch and European developments in harmonising data collection have contributed or will significantly contribute to improvements in the data situation for the ECHI indicators in the Netherlands. © 2015 Harbers et al. Source

Borgi M.A.,Cbs Therapeutics, Inc. | Rhimi M.,French National Institute for Agricultural Research | Kadri A.,University of Sfax
General Physiology and Biophysics | Year: 2014

The crystallization behaviour of the highly thermostable glucose isomerase from the Streptomyces sp. strain isolated from Tunisian soil was investigated using ammonium sulfate as a precipitating agent. We established phase diagrams at different temperatures and protein concentrations. It was found that the solubility increased with increasing temperature and decreased with increasing salt concentration. The temperature-dependent solubility was used to characterize the thermodynamic parameters of crystallization such as enthalpy, entropy and free energy. Source

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