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Chennai, India

Venkatesan S.,Cavinkare Research Center | Jayaganesh S.,UPASI Tea Research Foundation
Research Journal of Phytochemistry | Year: 2010

The excess potassium (K) application to the soil reduces the availability of magnesium (Mg) and vice versa due to antagonism. A pot culture experiment was carried out in which pots were filled with 4 kg of soil to which magnesium sulphate was added externally so as to have 100, 250, 500, 750,1000, 2000, 5000 and 10000 mg of Mg kg-1 of soil. Excess magnesium has induced some toxicity symptoms like development of coppery color along the marginal veins at the initial stage. The mid rib region was also slightly affected. Extensive coppery color developed all over the leaf surface and defoliation of leaf occurred during the final staged of toxicity. The plant, which received 10000 mg of Mg2+ kg-1 died on 20th day after imposing treatments and the plants, which received 5000 mg of Mg2+ kg-1, died on 45th day. The surviving plants were uprooted and separated into leaves, stem, root and soil, on which chemical analysis was carried out. Surprisingly, at any given treatment the accumulation of Mg in root was higher than that of leaf and stem. This study confirmed the antagonism existing between K and Mg and synergism existing between the P and Mg. The ammo acid content increased in tea leaf up to 1000 mg treatment and then gradually decreased. © 2010 Academic Journals Inc.


Jain S.,Vikram University | Bhimireddy N.R.,Vikram University | Kolisetty S.R.,Cavinkare Research Center
International Journal of ChemTech Research | Year: 2011

Knoevenagel condensation of various heteroaromatic aldehydes with active methylene compounds like malononitrile, ethyl cyanoacetate, barbituric acid, meldrums acid and dimedone proceeds smoothly with stirring under conventional heating. Twenty Knoevenagel condensation products were synthesized with excellent yields. The new compounds were also screened for their antibacterial activity. The work-up procedure is very simple and the products do not require further purification.


Kottur G.,UPASI Tea Research Foundation | Venkatesan S.,Cavinkare Research Center | Kumar R.S.S.,Harrisons Malayalam Ltd | Murugesan S.,UPASI Tea Research Foundation
Journal of the Science of Food and Agriculture | Year: 2010

Background: Quality of tea depends on the cultivar and climatic conditions. Biochemical pathways within the plant and climatic factors can result in noticeable changes in chemical composition, which determine the quality of tea. Black tea quality attributes are influenced by various forms of catechins, namely gallated, non-gallated, dihydroxylated and trihydroxylated catechins and their ratios. Hence the variations in grouped catechins and their synthesizing enzyme in relation to quality of south Indian black tea grown in different seasons and different cultivars were studied. Results: Gallated, non-gallated, dihydroxylated, trihydroxylated catechins and catechin index were significantly higher in crop shoots harvested during summer. A significant and wide diversity in various forms of catechins was noticed among the cultivars tested. Among the cultivars, UPASI-3 registered the higher amount of various forms of catechins and activity of phenylalanine ammonia lyase (PAL), followed by UPASI-9 and UPASI-17 respectively, while the lowest amount was exhibited by 'Assam' seedlings and TRI-2043. Conclusion: Overall quality as evaluated by tea tasters was positively correlated to the cultivars and seasons tested. This positive correlation can be attributed to higher levels of grouped catechins and PAL activity. Thus the contents of various forms of catechins could be themost important quality parameter of the south Indian black teas. © 2010 Society of Chemical Industry.


Kadam S.H.,VerGo Pharma Research | Paknikar S.K.,VerGo Pharma Research | Rao G.V.,Cavinkare Research Center
Natural Product Communications | Year: 2013

Structure 2 assigned presently to nardin is revised to that of valerenic acid (4), and structure 1 assigned presently to nardal is revised to that of valerenal (3). The names valerenic acid and valerenal have priority so the names nardin and nardal should no longer be used.


Kamakshi R.,Cavinkare Research Center
Journal of cosmetic science | Year: 2012

Skin-lightening cosmetics are in big demand across Asia, and the quest for fairness has led to identification of many new ingredients. The mechanisms underlying pigmentation have been researched extensively and the knowledge is being updated regularly. This review serves to list the ingredients that are commercially available for that purpose and the modes of action through which the lightening is effected. Skin-lightening ingredients are also classified based on their sources; it is significant that far more botanicals have made the list than have synthesized compounds. Tyrosinase inhibition as a means of skin lightening is still the most reported method, followed by other methods such as Mitf inhibition, down regulation of MC1R activity, interference with melanosomal transfer, and melanocyte loss.

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