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Sao Paulo, Brazil

The Universidade Católica de Santos is a private and non-profit Catholic university, located in Santos, the first university in the region of the city. It is one of the largest Brazilian universities. It is maintained by the Catholic Archdiocese of Santos.UNISANTOS's history began in 1951 when the Society was founded by Visconde de São Leopoldo. The initial goal was to establish the School of Law. Thereafter, the university expanded to include a school of Philosophy, science and Letters, Communication, Economics and Business, School of Architecture, School of Social Work, School of Nursing, School of Pharmacy and Biochemistry, and School of Engineering.On February 6, 1986, the Catholic UNISANTOS was recognized and became the first university in the region, under the auspices of the then Minister Marco Antônio Maciel under approval process 3924/76. Currently consisting of five learning centres, the UNISANTOS maintains more than 40 undergraduate courses, including programmes in Technology, five Masters courses recommended by Capes and MEC , science and the arts, and dozens of other courses linked to a humanistic tradition.As a member of the Brazilian Association of Community Universities, the UNISANTOS provides part of their revenue to provide funding for scholarships, free hospital visits, psychology clinics, and legal assistance, among others. Additionally, it maintains the Open University for the Elderly, a pioneer project in the region.Located in the littoral zone of the State of São Paulo, region known as "Baixada Santista," the law school of the Catholic UniSantos is among the best in the State, according to the Federal Council of the Bar Association of Brazil. The university is the only one to get the label "Federal Bar Association recommends," in three editions in which it was granted. It is also recognized for the high rate of students who pass the examination stage of the OAB and the Public Defender and Prosecutor, in addition to tendering for public service careers in the legal area as Magistrates, Prosecutors at the federal, state and municipal levels.The UNISANTOS has an agreement to exchange students with foreign institutions located in Portugal, Spain, Italy, France, Switzerland, Russia, Argentina, Venezuela, and Mozambique. Wikipedia.

Gollucke A.P.B.,Catholic University of Santos
Recent Patents on Food, Nutrition and Agriculture | Year: 2010

Grape polyphenols are associated with the prevention of diseases caused by oxidative stress. The present review discusses the most abundant polyphenols in red grapes as well as the recent food and beverage products developed with these natural antioxidant substances. Grape phenolic concentration and composition depend on agro-geographic factors and processing conditions. In humans, grape polyphenols demonstrated effects such as maintenance of endothelial function, increase in antioxidant capacity and protection against LDL oxidation. Recent patents regarding grape polyphenols show a tendency to return to natural products with a minimum use of severe extraction processes and organic solvents. The new products tend to use grape juice and wine as raw materials and maximize their polyphenolic contents. Grape derived polyphenolic foods, beverages and supplements suit effectively the current demand for antioxidant substances of nutritional interest. © 2010 Bentham Science Publishers Ltd.

Gollucke A.P.B.,Catholic University of Santos | Aguiar Jr. O.,Federal University of Sao Paulo | Barbisan L.F.,Sao Paulo State University | Ribeiro D.A.,Federal University of Sao Paulo
Journal of Medicinal Food | Year: 2013

Polyphenols are present in foods and beverages and are related to sensorial qualities such as color, bitterness, and astringency, which are relevant in wine, tea, grape juice, and other products. These compounds occur naturally in forms varying from simple phenolic acids to complex polymerized tannins. Thus, it is reasonable to expect that grape-derived products elaborated in the presence of skins and seeds, such as wine and grape juice, are natural sources of flavonoids in the diet. Carcinogenesis is a multistep process that is characterized by genetic, epigenetic, and phenotypic changes. With increasing knowledge of these mechanisms, and the conclusion that most cases of cancer are preventable, efforts have focused on identifying the agents with potential anticancer properties. The use of grape polyphenols against the carcinogenesis process seems to be a suitable alternative for either prevention and/or therapeutic purposes. The aim of this article is to show the molecular data generated from the use of grape polyphenols against carcinogenesis using in vivo and in vitro test systems. © Mary Ann Liebert, Inc. and Korean Society of Food Science and Nutrition.

Thome M.T.C.,Sao Paulo State University | Zamudio K.R.,Cornell University | Giovanelli J.G.R.,Sao Paulo State University | Haddad C.F.B.,Sao Paulo State University | And 2 more authors.
Molecular Phylogenetics and Evolution | Year: 2010

The Plio-Pleistocene refugia hypothesis recently gained support in explaining Brazilian Atlantic Forest megadiversity from combined analyses of species paleodistributions and genetic diversity. Here we examine genetic differentiation and historical distributions in the Rhinella crucifer group of toads, endemic to and widely distributed within this biome. We analyzed sequences of mitochondrial (control region, ND1, and ND2) and nuclear (β-crystallin and rhodopsin) DNA markers from 65 individuals representing five species. We found deep structure across the range at mitochondrial markers; genetic diversity is geographically structured in four main haplotype clades with the oldest divergence, dated to the Pliocene, between the southernmost populations and other regions of the species' range. Remaining populations are distributed in haplotype clades that may have diverged throughout the Pleistocene. Our paleoecological distribution models support a scenario of habitat fragmentation associated with glacial cycling, but we found limited congruence of phylogeographic patterns with the refugia. We found that some genetic breaks geographically coincide with putative barriers associated to neotectonic activity, but finer-scale sampling will be necessary to test the relative importance of distinct isolation mechanisms. Overall, the data refute the recently proposed hypothesis of a southern Holocene colonization of the Atlantic Forest from northern refugia, suggesting instead persistence of forested habitats in the south. Our unexpected results underscore the need to consider distinct organismal histories in planning biome-level conservation. We discuss species correspondence to clades recovered in our phylogenetic analyses. © 2010 Elsevier Inc. All rights reserved.

Gollucke A.P.B.,Catholic University of Santos | Ribeiro D.A.,Federal University of Sao Paulo
Recent Patents on Food, Nutrition and Agriculture | Year: 2012

We presently discuss the use of grape polyphenols for promoting human health and disclose recent patents on the subject. The biological effects of grape polyphenols in human and experimental models demonstrate antioxidant properties closely associated with the maintenance of endothelial function, increase in antioxidant capacity, protection against LDL oxidation and neuroprotective effects. Recent patents regarding grape polyphenols show a tendency to return to natural products with a minimum use of severe extraction processes and organic solvents. Moreover, the recent patents regarding human health show more pharmaceutical use of grape juice and other polyphenol-rich products. The application of such products in clinical trials as a substitute or co-adjuvant with drugs may be useful in future research. © 2012 Bentham Science Publishers.

This paper is about interdisciplinary post-graduation education from the perspective of Social Sciences and Humanities in Health supervisors and post-graduate students trained in health. Difficulties regarding post-graduation in general and specifically for health care professionals will be discussed. Some tensions about the production of knowledge from different disciplinary perspectives will be considered. A dialogue is necessary between supervisor, to whom theoretical framework takes a prominent place, and student, whose practice is guided by intervention. Theoretical dialogue between supervisor and student is asymmetrical and implies moral and ethical tensions for both. Geertz's term "anthropological irony" (2000) is used to discuss the relationship between supervisor and student. Finally, a reflection is proposed on possible attitudes and expectations in this relationship. We need a debate to discuss the effective contributions of this relationship and what is intended as interdisciplinary research.

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