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Dalmacio Velez Sarsfield, Argentina

The Catholic University of Santiago del Estero is an institution created by a group of lay Catholics in collaboration with the Congregation of the Brothers of Mercy, and was inaugurated on June 21, 1960, as the Instituto Universitario San José de Ciencias Políticas, Sociales y Económicas.Its main, Santiago del Estero campus was built in 1979, and the institution maintains campuses in San Salvador de Jujuy , Olivos , and Rafaela . The main campus is known for its arboretum, the Estación Experimental Fernández, which features over 15,000 trees . Wikipedia.

Bessega C.,University of Buenos Aires | Pometti C.,University of Buenos Aires | Ewens M.,Catholic University of Santiago del Estero | Saidman B.O.,University of Buenos Aires | Vilardi J.C.,University of Buenos Aires
Genetica | Year: 2015

Signals of selection on quantitative traits can be detected by the comparison between the genetic differentiation of molecular (neutral) markers and quantitative traits, by multivariate extensions of the same model and by the observation of the additive covariance among relatives. We studied, by three different tests, signals of occurrence of selection in Prosopis alba populations over 15 quantitative traits: three economically important life history traits: height, basal diameter and biomass, 11 leaf morphology traits that may be related with heat-tolerance and physiological responses and spine length that is very important from silvicultural purposes. We analyzed 172 G1-generation trees growing in a common garden belonging to 32 open pollinated families from eight sampling sites in Argentina. The multivariate phenotypes differ significantly among origins, and the highest differentiation corresponded to foliar traits. Molecular genetic markers (SSR) exhibited significant differentiation and allowed us to provide convincing evidence that natural selection is responsible for the patterns of morphological differentiation. The heterogeneous selection over phenotypic traits observed suggested different optima in each population and has important implications for gene resource management. The results suggest that the adaptive significance of traits should be considered together with population provenance in breeding program as a crucial point prior to any selecting program, especially in Prosopis where the first steps are under development. © 2014, Springer International Publishing Switzerland.

Villavicencio G.,Catholic University of Santiago del Estero
ACM International Conference Proceeding Series | Year: 2011

One affective way to carry out a program comprehension process is by refactoring the source code. In this paper we explore this approach in the functional programming paradigm, on Haskell programs specifically. As result, we have identified many correlations between the traditional (procedural and object-oriented) program comprehension process and the so called understanding-oriented refactorings, in the functional programming context. Besides, we have identified a catalog of refactorings used to improve program efficiency which, applied in reverse order, are valuable for program understanding purposes. Coupled to these refactorings, there is a calculational process by (means of) which we obtain a full formal description of program functionality. All together, a bottom-up program comprehension strategy in the functional setting is described. © 2011 ACM.

Villavicencio G.,Catholic University of Santiago del Estero
Proceedings of the European Conference on Software Maintenance and Reengineering, CSMR | Year: 2012

This research line proposes the classification of refactoring techniques according to two opposite program properties: understanding and efficiency, being the former useful for maintenance while the latter for executing. Understanding-oriented refactoring and efficiency-oriented refactoring are considered the inverses of each other. Thus, through the application of the first sort of refactoring, understanding can be improved but efficiency can be affected. On the other hand, by applying the second sort of refactoring, efficiency can be improved but understanding can be damaged. So, the challenge to be faced here is to transform a software artifact through the application of a sequence of understanding-oriented refactoring, and to execute maintenance with the most appropriate version obtained. After that, we plan to restore its original efficiency by the application of the opposite sequence of refactorings, i.e. efficiency-oriented refactoring. In this way, a new maintenance scenario is outlined. Up to now, this ongoing research is being carried out in the functional setting. © 2012 IEEE.

Olivera G.C.,Instituto Nacional Of Parasitologia Dr Mario Fatala Chaben | Albareda M.C.,Instituto Nacional Of Parasitologia Dr Mario Fatala Chaben | Alvarez M.G.,Hospital Eva Peron | De Rissio A.M.,Instituto Nacional Of Parasitologia Dr Mario Fatala Chaben | And 8 more authors.
Microbes and Infection | Year: 2010

Trypanosoma cruzi-specific immune responses were evaluated in a total of 88 subjects living in areas endemic of Chagas disease of Argentina by IFN-γ ELISPOT assays and immunoblotting. Positive T. cruzi antigen-induced IFN-γ responses were detected in 42% of subjects evaluated (15/26 positive by conventional serology and 22/62 seronegative subjects). Using immunoblotting, T. cruzi-specific IgG reactivity was detected in all seropositive subjects and in 11% (7/61) of subjects negative by conventional serology. Measurements of T cell responses and antibodies by immunoblotting, in conjunction with conventional serology, might enhance the capability of detection of exposure to T. cruzi in endemic areas. © 2010 Elsevier Masson SAS. All rights reserved.

Bessega C.,University of Buenos Aires | Pometti C.L.,University of Buenos Aires | Ewens M.,Catholic University of Santiago del Estero | Saidman B.O.,University of Buenos Aires | Vilardi J.C.,University of Buenos Aires
European Journal of Forest Research | Year: 2016

Spatial genetic structure (SGS) in plants is primarily determined by the interaction between pollen and seed dispersal, but it is strongly affected by both evolutionary and ecological processes. SGS studies in forest species also allow evaluating the consequences of human-mediated disturbance on pollen and seed movement and designing strategies of sustainable use of native forest resources. The present paper compares fine-scale SGS between two populations of Prosopis alba: Fernandez-Forres (FF) and Campo Duran (CD), based on the variation of 12 SSR markers. Populations show different history, management, and levels of disturbance. FF is highly disturbed and fragmented by agricultural activity and stock-breeding. Although no significant differences were observed in genetic variability parameters, highly significant genetic differentiation was detected with virtually no admixture between populations. SGS was positive and significant at short distances only in the non-disturbed population of CD. Accordingly, estimated neighborhood size and effective gene dispersal are higher in FF than in CD. This result might be explained by the higher incidence of livestock in seed dispersal and the patchy structure favoring longer pollen movement and artificial thinning and selection in FF. The results are relevant to conservation and breeding programs, suggesting that the distance between seed trees to be sampled should be larger than 22 m, the estimated distance of significant SGS in P. alba. © 2016 Springer-Verlag Berlin Heidelberg

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