Bucheon, South Korea

Catholic University of Korea

www.catholic.ac.kr
Bucheon, South Korea

The Catholic University of Korea is a private Roman Catholic institution of higher education in South Korea. It operates campuses in Seoul and in the neighboring Bucheon City. The university's medical school, considered as one of the most prestigious in South Korea, has eight affiliated hospitals in major cities of the country. The university has been consistently ranked as one of the premier universities in South Korea and has been regarded in both national and international university rankings. Wikipedia.

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Provided is a blood culture treatment technology, including a novel treatment technology of performing pretreatment of a positive blood culture to effectively remove foreign substances such as cells, etc., thereby omitting a subculturing process on a solid medium and realizing rapid selection of antimicrobial agents for patients. The pretreatment method of a positive blood culture sample for bacterial identification and antimicrobial susceptibility testing includes preparing a first liquid culture by centrifuging a portion of a liquid medium including the positive blood culture sample, washing a precipitate thus centrifuged with a solution including sodium chloride, and then suspending the precipitate in the solution including sodium chloride, and preparing a second liquid culture by passing the first liquid culture thus prepared through a pretreatment filter including a mesh structure.


Patent
Catholic University of Korea | Date: 2017-03-03

There is provided a thermosensitive biodegradable hydrogel including MPEG-PCL to which a cell-adhesive peptide binds, and MPEG-PCL. The thermosensitive biodegradable hydrogel has excellent cellular adhesiveness while maintaining thermosensitivity of polymers intact, and is biodegradable in vivo after a predetermined period of time.


Patent
Catholic University of Korea | Date: 2017-01-18

The present disclosure relates to a use of H2AFZ as a hepatocellular carcinoma (HCC) biomarker and more particularly, to a marker for diagnosing hepatocellular carcinoma consisting of a H2AFZ gene or an expression protein H2A.Z.1 thereof, a composition for diagnosing or estimating prognosis of HCC, a method for diagnosing or estimating prognosis of HCC, a method of detecting a biomarker for diagnosing or estimating prognosis of HCC, a screening method of an HCC therapeutic agent, and a pharmaceutical composition for preventing or treating HCC. As it is verified that the expression level of the H2AFZ gene according to the present disclosure is increased in an HCC tissue or HCC cells compared to a non-HCC tissue or non-HCC cells, in the case of using the H2AFZ gene as the marker for diagnosing the HCC, the HCC can be rapidly and accurately diagnosed and predicted in early stages and the H2AFZ gene can be used as a target for developing a therapeutic agent for preventing or treating the HCC.


Patent
Catholic University of Korea | Date: 2016-07-07

Provided is a technique of accurately forming a shape of a scaffold demanding high precision and fast manufacturing the scaffold with low costs, so that the scaffold for dental treatment may be immediately placed after tooth extraction and may be accurately placed in a tooth extraction socket. A method of manufacturing a scaffold for treatment of a tooth extraction socket includes manufacturing, by using a three-dimensional (3D) printer, a 3D model comprising alveolar bones and teeth, which are distinguished therebetween, from a medical image file that is a medical image file (DICOM file) of dental computerized tomography (CT) data; performing virtual tooth-extraction by removing, from the manufactured 3D model, a region corresponding to a tooth in a tooth-extraction target area; and manufacturing, by using the 3D printer, a scaffold to be placed in an actual tooth extraction socket according to a shape of a tooth extraction socket that exists in the manufactured 3D model as a result of the virtual tooth-extraction.


Patent
Catholic University of Korea | Date: 2017-02-15

The present invention relates to a novel compound capable of effectively preventing and treating immune diseases and a use thereof. The novel compound of the present invention has effects of inhibiting the formation of proinflammatory cytokines, increasing the activity of regulatory T cells having immunoregulatory functions, inhibiting the production of autoantibodies to regulate excessive immune responses, and inhibiting the differentiation to osteoclasts, and thus can be used for treating immune diseases, such as autoimmune diseases, inflammatory diseases, and transplant rejection diseases, which are caused by abnormal regulation of various kinds of immune responses.


Patent
Catholic University of Korea | Date: 2017-03-08

The present invention relates to a method for predicting the prognosis of acute myeloid leukemia relapse. According to the present invention, the prognosis of acute myeloid leukemia relapse can be predicted by analyzing changes in a bone marrow microenvironment during the early diagnosis of leukemia.


Patent
Catholic University of Korea | Date: 2016-07-07

Provided is a technique of manufacturing a scaffold for jaw bone or bone reconstruction, by which a scaffold is fast and accurately manufactured to be placed instantly after treatment and simultaneously a scaffold is manufactured to be stably placed in an irregular recipient site or a wide region such as a tumor. A method of manufacturing a block type scaffold include generating a three-dimensional (3D) image of a scaffold to be placed in a recipient site for bone reconstruction by using a medical image file (DICOM file) of CT image data, dividing the 3D image of the scaffold into a plurality of block images, and manufacturing the scaffold by outputting the 3D image of the scaffold by using a 3D printer, wherein a plurality of 3D objects corresponding to the plurality of block images are output to be separable from one another.


Patent
Catholic University of Korea | Date: 2016-08-12

Provided is an orthodontic plate to be fixed to a mandibular ramus, the orthodontic plate including a fixing part implanted into a retromolar fossa portion of a mandible in a mouth, the retromolar fossa portion being near a molar; a hook part connected to the fixing part, and dynamically connected to orthodontic appliances placed at lower teeth for mandibular orthodontics; and a connection part connecting the fixing part and the hook part, the connection part projecting and being sloped from a front end surface including the fixing part toward a front end surface including the hook part, so as to allow the hook part to be positioned without being interrupted by the lower teeth.


Patent
Catholic University of Korea | Date: 2016-10-31

The present invention relates to a novel compound capable of effectively preventing and treating immune diseases and a use thereof. The novel compound of the present invention has effects of inhibiting the production of inflammatory cytokines, increasing the activity of regulatory T cells having immunoregulatory functions, inhibiting the production of auto-antibodies to regulate excessive immune responses, and inhibiting the differentiation of osteoclasts, and thus can be used for treating immune diseases, such as autoimmune disease, inflammatory disease, and transplant rejection diseases, which are caused by abnormal regulation of various kinds of immune response


The present invention relates to a composition for preventing or treating mucositis comprising NecroX. It was found that NecroX has effects of reducing the disease mortality rate by means of radiotherapy or chemotherapy in a NecroX administration group, protecting intestinal functions, inhibiting destruction of intestinal mucous membrane, and proliferating the cells present in intestines. NecroX may be used for a pharmaceutical composition for preventing or treating mucositis, an anti-cancer adjuvant, or a food composition.

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