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Yaounde, Cameroon

The Catholic University of Central Africa is a private Roman Catholic university in Yaoundé, Cameroon. Wikipedia.

Vouking M.Z.,Center for the Development Best Practices in Health | Tamo V.C.,Center for the Development Best Practices in Health | Tadenfok C.N.,Catholic University of Central Africa
Pan African Medical Journal | Year: 2013

Buruli ulcer (BU) is a cutaneous neglected tropical disease caused by Mycobacterium ulcerans. Synthesizing the evidence on their efficacy of antibiotic in the management of BU can help to better define their roles, identify weaknesses and inform clinicians on relevant measures than can be used to control BU. Our objectives is to assess the clinical efficacy of Rifampicin-Streptomycin given for 8 weeks of treatment of early M. ulcerans infection. We searched the following electronic databases from January 2005 to July 2012: Medline, EMBASE (Excerpta Medica Database), The Cochrane Library, Google Scholar, CINAHL (Cumulative Index to Nursing and Allied Health Literature), WHOLIS (World Health Organization Library Database), LILACS (Latin American and Caribbean Literature on Health Sciences) and contacted experts in the field. There were no restrictions to language or publication status. All study designs that could provide the information we sought for were eligible provided the studies were conducted in the third world. Critical appraisal of all identified citations was done independently by three authors to establish the possible relevance of the articles for inclusion in the review. Of the 115 studies, 09 papers met the inclusion criteria. The duration of treatment ranged from 8 to 48 weeks depending on the severity. Oral chemotherapy alone obtained a curative rate of 50%. The "dual" mode of treatment (surgery + chemotherapy) reduced hospital admission period from 90 to 39.8 days, that's to 44.2%. This treatment for early stages could therefore replace surgery and in severe cases, is an indispensable aid before surgery. These results confirmed that the daily administration of Rifampicin and Streptomycin is an effective treatment for M. ulcerans infection in an early stage. Subsequent systematic reviews should be conducted to determine if antibiotics could heal injuries without resorting to surgery and to compare different treatment durations. © Marius Zambou Vouking et al. Source

Vouking M.Z.,Center for the Development of Best Practices in Health | Vouking M.Z.,Center Regional Delegation | Tamo C.V.,Center for the Development of Best Practices in Health | Tadenfok C.N.,Catholic University of Central Africa
Pan African Medical Journal | Year: 2014

Introduction: Intestinal parasites are more common in people with HIV, especially in tropical developing countries. This cross-sectional study was carried out to assess the prevalence of intestinal parasites among people with HIV at the Yaoundé Central Hospital Accredited Treatment Centre. Methods: Structured questionnaires were used to collect clinical information after obtaining consent from the participants. Stool samples were collected from 207 HIV-positive patients for the investigation of intestinal pathogens using direct microscopy, formalin-ether concentration, ZiehlNeelsen modified and Kato-Katz methods. Data was analyzed using Epi-info version 3.4.1. and Microsoft Office Excel 2007. Results: A total of 207 people were recruited. Eighty (38.65%) were male and 127 (61.35%) were female. The overall prevalence of intestinal parasite infections was 57.48% (119/207). The parasites detected in our study population included Entamoeba coli (22.68%), Ascarislumbricoïdes (22.68%), Entamoebahistolytica(15.93%), Cryptosporidium spp (12.60%), Isospora belli (10.08%), Trichuristrichiura (7.60%), Strongyloïdesstercoralis (5.88%), Ancylostomaduodenale and Necatoramericanus (2.52%). Conclusion: At the end of our study, it appears that intestinal parasites still occupy an important place among HIV-positive patients. © Marius Zambou Vouking et al. Source

Vouking M.Z.,Center for the Development of Best Practices in Health | Evina C.D.,Center for the Development of Best Practices in Health | Tadenfok C.N.,Catholic University of Central Africa
Pan African Medical Journal | Year: 2014

The World Health Organization (WHO) estimated in 2012 that 287,000 maternal deaths occurred in 2010; sub-Saharan Africa (56%) and Southern Asia (29%) accounted for the global burden of maternal deaths. Men are also recognized to be responsible for the large proportion of ill reproductive health suffered by their female partners. Male involvement helps not only in accepting a contraceptive but also in its effective use and continuation. The objectives were to assess men's knowledge, attitude, and practice of modern contraceptive methods; determine the level of spousal communication about family planning decision making; and investigate the correlates of men's opinion about their roles in family planning decision making. We searched the following electronic databases from January 1995 to December 2013: Medline, Embase, CINAHL, LILAS, International Bibliography of Social Sciences, Social Services Abstracts, and Sociological Abstracts. Along with MeSH terms and relevant keywords, we used the Cochrane Highly Sensitive Search Strategy for identifying reports of articles in PubMed. There were no restrictions to language or publication status. Of 137 hits, 7 papers met the inclusion criteria. The concept of family planning was well known to men. In the Nigerian study, almost (99 %) men were aware of the existence of modern contraceptives, and most of them were aware of at least two modern methods. Awareness of the condom was highest (98 %). In the Malawi study, all of the participants reported that they were not using contraception before the intervention. In Ethiopia, above 90% of male respondents have supported and approved using and choosing family planning methods, but none of them practiced terminal methods. Generally, more male respondents disagreed than agreed that men should make decisions about selected family planning issues in the family. Decision-making dynamics around method choice followed a slightly different pattern. According to female participants, decisions regarding method choice were equally made by women or jointly, with male-dominated decisions falling last. There are many challenges to increase male involvement in family planning services. So far very few interventions addressing these challenges have been evaluated scientifically. Health education campaigns to improve beliefs and attitudes of men are absolutely needed. Additionally, improving accessibility, affordability, availability, accommodation and acceptability of family planning service venues will make them more attractive for male partners. © 2014, Marius Zambou Vouking et al. Source

Asangbeh S.L.,Catholic University of Central Africa | Sobngwi J.L.,Catholic University of Central Africa | Ekali G.L.,National AIDS Control Committee | Eyoum C.,Laquintine Hospital | Msellati P.,Institute Recherche et Developpement
AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV | Year: 2016

Depression in people living with HIV/AIDS (acquired immune-deficiency syndrome) (PLWHA) increases risky HIV transmission behaviour, disease progression to AIDS, negatively affects drug adherence and is thus a risk for the development of drug-resistant strains. This study sought to identify predictors of depression in rural Cameroon. A cross-sectional analytic study was carried out from September 2013 to November 2013 in the Mbengwi district hospital of the North West region. We measured depression (PHQ-9 (nine-item Patient Health Questionnaire)), clinical and demographic characteristics of patients on antiretroviral therapy (ART). Means, proportions and a stepwise logistic regression model were fit to describe participants characteristics and predictors of depression in the study population. Of the 202 recruited patients, 58(28.7%) had a positive depression screen. Independent predictors of depression included monthly income less than 20,000 FCFA (US$40), (adjusted odds ratio (aOR) = 2.47; 95% CI = 1.18-5.18), CD4 count <200cls/μl (aOR = 7.56; 95% CI = 2.46-23.30) and presence of AIDS symptoms (aOR = 4.29; 95% CI = 2.09-8.81). There was no significant correlation between duration on ART, marital status, age, gender and depression. Early diagnosis and treatment of depressed patients need to be incorporated into intervention programmes, which might improve patient outcomes. More research is needed to investigate the impact of antidepressant therapy in PLWHA on the evolution of treatment. © 2015 Taylor & Francis. Source

Atabonkeng E.P.,Catholic University of Central Africa | Adiogo D.,University of Douala | Emmanuel E.M.,University of Yaounde I | Herve O.F.,Catholic University of Central Africa | And 2 more authors.
Archives of Rheumatology | Year: 2015

Objectives: This study aims to assess the prevalence of rheumatoid factor (RF) of immunoglobulin M nature in the Cameroonian population and the influence of demographic factors on its production. Patients and methods: A total of 369 subjects (125 males and 244 females; mean age 42.36±15.73 years; range 15-88 years) were tested from five regions of Cameroon (Center, East, Far North, Littoral and West) between July 2012 and December 2012. Whole blood was collected from each participant and the serum was used for immunoglobulin M RF assay using the RF-IMMESCO test (agglutination technique). Results: The prevalence of RF in the whole population was 5.4%, with a female to male ratio of 2.4. RF was present in all age groups, but especially in participants of 30 to 60 years of age. The Center region had the highest prevalence (7.5%), while the West region had the lowest prevalence (2.2%). However, there was no significant difference between studied regions (p>0.05). Of the 369 participants tested, 257 (69.6%) complained of having suffered joint pain at one time or another while 112 did not complain of joint pain. The prevalence of RF was 6.22% in the former group and 3.57% in the latter. Among those 50 to 70 years of age, nearly 90% had at least one painful joint. Conclusion: The presence of RF in the study population may lead to joint diseases, which are more common disabling diseases among the inhabitants of Cameroon. Further studies are needed to bring more insight on the prevalence of RF in Cameroon. © 2015 Turkish League Against Rheumatism. All rights reserved. Source

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