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Washington, DC, United States

The Catholic University of America is a private university located in Washington, D.C. in the United States. It is a pontifical university of the Catholic Church in the United States and the only institution of higher education founded by the U.S. Catholic bishops. Established in 1887 as a graduate and research center following approval by Pope Leo XIII on Easter Sunday, the university began offering undergraduate education in 1904. The university's campus lies within the Brookland neighborhood, known as "Little Rome", which contains 60 Catholic institutions, including Trinity Washington University and the Dominican House of Studies.It has been called one of the 25 most underrated colleges in America, one of the nation's best colleges by the Princeton Review, one of the best values of any private school in the country by Kiplinger's, "one of the most eco-friendly universities in the country," was awarded the "highest federal recognition an institution can receive" for community service, and has been recommended by the Cardinal Newman Society in The Newman Guide to Choosing a Catholic College.CUA's programs emphasize the liberal arts, professional education, and personal development. The school stays closely connected with the Catholic Church and Catholic organizations. The American Cardinals Dinner is put on by the residential U.S. cardinals each year to raise scholarship funds for CUA. The university has a long history of working with the Knights of Columbus; the university's law school and basilica have dedications to the involvement and support of the Knights.The university has been visited twice by reigning Popes. Pope John Paul II visited on October 7, 1979. On April 16, 2008, Pope Benedict XVI gave an address on Catholic education and academic freedom on campus. Wikipedia.

The present invention provides compositions and methods for converting hazardous waste glass into safe and usable material. In particular, the present invention provides compositions and methods for producing ceramic products from toxic-metal-containing waste glass, thereby safely encapsulating the metals and other hazardous components within the ceramic products.

University of Maryland College Park and Catholic University of America | Date: 2013-08-20

Complexing or chelating agents that offer strong, selective bonding with uranium as well as a broad pH range of effectiveness, specifically including the pH range around 8.2, together with the acrylic double bonds required for radiation-induced grafting on polymers to remove uranium from a solution such as seawater. The novel adsorbing species are phosphorus-containing molecules, in particular organic phosphates, phosphonates and phosphoric acids. Organic phosphorus compounds, for example, organic phosphates, phosphonates, and phosphoric acids, are attached to polymer fibers to form fibers, fiber fabrics or membranes that are effective, or show activity, in uranium adsorption.

Described is T4 DNA packaging machine comprising: one or more DNA molecules packaged in a head of the T4 DNA packaging machine, one or more Hoc-fused proteins displayed on the head of the T4 DNA packaging machine, and one or more Soc-fused proteins displayed on the head of the T4 DNA packaging machine. Also described are methods of making and using such a T4 DNA packaging machine.

Catholic University of America | Date: 2014-07-02

Complex viruses are assembled from simple protein subunits by sequential and irreversible assembly. During genome packaging in bacteriophages, a powerful molecular motor assembles at the special portal vertex of an empty prohead to initiate packaging. An aspect of the invention relates to the phage T4 packaging machine being highly promiscuous, translocating DNA into finished phage heads as well as into proheads. Single motors can force exogenous DNA into phage heads at the same rate as into proheads and phage heads undergo repeated initiations, packaging multiple DNA molecules into the same head. This shows that the phage DNA packaging machine has unusual conformational plasticity, powering DNA into an apparently passive capsid receptacle, including the highly stable virus shell, until it is full. These features allow for the design of a novel class of nanocapsid delivery vehicles.

Catholic University of America | Date: 2013-11-27

Described herein is a soluble HIV-1 retrovirus transmembrane glycoprotein gp41 trimer (Soc-gp41M-Fd) containing a partial ectodomain and the cytoplasmic domain, that is fused to the small outer capsid (Soc) protein of bacteriophage T4 and the Foldon domain of the bacteriophage T4 fibritin (Fd). The gp41 trimer that has a prehairpin structure could be utilized to understand the mechanism of viral entry and as a candidate for development of HIV-1 vaccines, diagnostics and therapeutics. Other secondary embodiments of the gp41 proteins containing different modifications are also disclosed. According to one embodiment, the gp41 trimer is further attached to a cell penetration peptide (CPP). Methods of producing gp41 trimers are also disclosed.

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