Sellanes D.,Catedrade Quimica Farmaceutica DQO |
Campot F.,Catedrade Quimica Farmaceutica DQO |
Nunez I.,Catedrade Quimica Farmaceutica DQO |
Lin G.,Catedrade Inmunologia |
And 6 more authors.
Tetrahedron | Year: 2010
The synthesis of key fragments of scleritodermin A, their assembly, and their biological evaluation as cytotoxic and anthelmintic were performed.Highlights of the synthetic route include formation of the a-ketoamide linkage and use of stereocontrolled reactions.Open analogs of this natural product were obtained using a convergent strategy. © 2010 Elsevier Ltd.All rights reserved. Source