Catedrade Quimica Farmaceutica DQO

Montevideo, Uruguay

Catedrade Quimica Farmaceutica DQO

Montevideo, Uruguay

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Sellanes D.,Catedrade Quimica Farmaceutica DQO | Campot F.,Catedrade Quimica Farmaceutica DQO | Nunez I.,Catedrade Quimica Farmaceutica DQO | Lin G.,Catedrade Inmunologia | And 6 more authors.
Tetrahedron | Year: 2010

The synthesis of key fragments of scleritodermin A, their assembly, and their biological evaluation as cytotoxic and anthelmintic were performed.Highlights of the synthetic route include formation of the a-ketoamide linkage and use of stereocontrolled reactions.Open analogs of this natural product were obtained using a convergent strategy. © 2010 Elsevier Ltd.All rights reserved.

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