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Santa Margherita di Belice, Italy

Shanahan J.,University of Limerick | Bhriain O.,University of Limerick | Morris M.E.,La Trobe University | Volpe D.,Casa di Cura Villa Margherita | Clifford A.M.,University of Limerick
Complementary Therapies in Medicine | Year: 2016

Objective: As the number of people diagnosed with Parkinson's disease increases, there is a need to develop initiatives that promote health and wellbeing and support self-management. Additionally, as exercise may slow physical decline, there is a need to develop methods that facilitate greater engagement with community-based exercise. The aim of this study is to examine the needs of (1) people with Parkinson's disease and (2) set dancing teachers to enable the development of participant-centred community set dance classes. Methods: A mixed methods study design was used. Two consensus group discussions using nominal group technique were held to (1) identify factors pertaining to the needs of people with Parkinson's disease from a set dance class and (2) the educational needs of set dancing teachers to enable them to teach set dancing to people with Parkinson's disease. Group discussions began with silent generation of ideas. A round-robin discussion and grouping of ideas into broader topic areas followed. Finally, participants ranked, by order of priority (1-5), the topic areas developed. Final data analysis involved summation of participants' ranking scores for each topic area. Results: Rich information on the needs of people with Parkinson's disease from a dance class and the educational guidance sought by set dancing teachers was gathered. Topic areas developed include "teaching method" for set dances and "class environment". Conclusion: Accessing community exercise programmes is important for this population. The results of this study will inform the development of an educational resource on Parkinson's disease for set dancing teachers. This resource may facilitate a larger number of teachers to establish sustainable community set dancing classes for people with Parkinson's disease. © 2016 Elsevier Ltd.


Piacentino M.,San Bortolo Hospital | Zambon G.,San Bortolo Hospital | Pilleri M.,Casa di Cura Villa Margherita | Bartolomei L.,San Bortolo Hospital
Journal of Neurosurgical Sciences | Year: 2013

Aim. Intracranial hemorrhage is an infrequent but potentially devastating complication associated with the placement of electrodes for deep brain stimulation (DBS). The objective of this retrospective review is to compare the risk of hemorrhage before and after the introduction of image-guided neuronavigation for the implant of electrodes for DBS. Methods. We reviewed all DBS implant performed at our Institute between 1998 and 2010. In 63 of the 106 patients, the targeting was based on ventriculography and merge of CT/MRI. After 2006, in the latter 43 procedures, we introduced targeting based on the merging of angio CT and MRI.. In both implant techniques, microelectrode recording (MER) was used to better define the target. All DBS procedures were performed by a single surgeon (M.P.). Patients had postoperative imaging (MRI or CT) 4-24 h following surgery. Results. In the group of patients implanted with the first targeting technique, 3 hematomas occurred and all of them solved with sequelae (one residual weakness and two hemiplegias.) After the introduction of neuronavigator, 2 hemorrhages occurred, one solved without sequelae while the second resulted in epileptic seizures. Conclusion. Although the incidence of hemorrhage occurred before and after the use of neuronavigation is the same, the severity is lower in the neuronavigated procedures. Targeting based on the merging of CT angiography and MRI T1/T2 seemed to increase the safety of the lead placement reducing the risk of sequelae related to bleeding. The use of MER was not found to be correlated with an increased hemorrhage rate.


Mioni G.,University of Padua | Stablum F.,University of Padua | Prunetti E.,Casa di Cura Villa Margherita | Grondin S.,UniversiteLaval
Journal of Affective Disorders | Year: 2016

Several studies reported temporal dysfunctions in anxious and depressed patients. In particular, compared to controls, anxious patients report that time is passing fast whereas depressed patients report that time passes slowly. However, in some studies, no differences between patients and controls are reported. Direct comparison between studies may be complex because of methodological differences, including the fact of conducting investigations with different temporal ranges. In the present study, we tested a group of anxious patients, a group of depressed patients, and a control group with two temporal tasks (time reproduction and time production) with the same temporal intervals (500, 1000 and 1500 ms) to further investigate the presence and cause of patient's temporal dysfunctions. Results showed that, compared to controls, anxious patients under-reproduced temporal intervals and depressed patients over-produced temporal intervals. The results suggest that time dysfunction in anxious patients would be mainly due to an attentional dysfunction whereas temporal dysfunction in depressed patients would be mainly due to variations in the pulse's emission rate of the pacemaker. © 2016 Elsevier B.V. All rights reserved.


Piacentino M.,San Bortolo Hospital | D'Andrea G.,Casa di Cura Villa Margherita | Perini F.,San Bortolo Hospital | Volpin L.,San Bortolo Hospital
World Neurosurgery | Year: 2014

Objective: On the basis of recent findings about the pathophysiology of cluster headache and through the experience reported in recent literature, we have reviewed the outcome of four patients affected by drug-resistant cluster headache treated in our department by posterior hypothalamic deep brain stimulation with a follow-up of more than 5 years. Methods: Between 2004 and 2006, we selected four patients affected by cluster headache. The diagnosis was based on the International Classification of Headache Disorders II criteria, and all patients were refractory to drug therapy. Under local anesthesia they underwent stereotactic positioning of a stimulation electrode within the posterior hypothalamus, ipsilateral to the site of pain. An intraoperative neurophysiological test stimulation was performed to assess possible side effects and symptoms related to hypothalamic neuronal activity. A second surgery was then performed with the patient under general anesthesia to implant the extension cable and the implantable pulse generator. Results: After 5 years of follow up, all patients had a valuable benefit with a reduction in episode frequency from 90% to 50% associated with a decrease in pain intensity perception. Conclusion: The long-lasting pain reduction and the improvement in the patients' symptoms should be considered a real positive prospective, not only because there was uncertainty about the persistence of the beneficial effects at a long-term follow-up, but also for the improvement of the quality of life. The stimulation can restore important aspects concerning the psychic condition that very often constitutes an important limiting factor in normal daily life for this type of patient.


Shanahan J.,University of Limerick | Morris M.E.,La Trobe University | Bhriain O.N.,University of Limerick | Volpe D.,Casa di Cura Villa Margherita | And 2 more authors.
Complementary Therapies in Clinical Practice | Year: 2015

Objective: To investigate if community-based Irish set dancing is feasible in Irish adults with Parkinson's disease. Methods: Over an eight week period, ten participants attended one set dancing class per week and completed a home programme in parallel. Feasibility was assessed by monitoring adverse effects, participants' verbal feedback, compliance rates and feedback from an exit questionnaire. Participants were assessed using the Berg balance scale, 6-min walk test, UPDRS-3 and PDQ-39, before and after the intervention. Results: No adverse effects were detected. Attendance at classes was 86%. Compliance with the home programme was 67%. Findings from the exit questionnaire showed participants enjoyed participating and reported improvements in aspects of health including balance. Quality of life improved with the dance programme and there was a trend toward improvement on the UPDRS-3. Conclusion: These findings suggest community-based Irish set dancing is a feasible form of exercise that can positively influence quality of life. © 2014 Elsevier Ltd.

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