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Pedrosa P.,University of Coimbra | Pedrosa P.,University of Porto | Pedrosa P.,University of Minho | Fiedler P.,TU Ilmenau | And 11 more authors.
Sensors and Actuators, B: Chemical | Year: 2017

We propose a novel alginate-based hydrogel as an alternative to the traditional EEG electrolytic gels. The new product is injected into the electrode cap cavities in the form of a viscous liquid, just like a commercial electrolytic gel, but it forms a solid and homogeneous hydrogel shortly after application. The solid hydrogel substantially reduces the risks of gel leaking from the electrode cavities and it showed first evidence of enabling a faster and easier cleaning of the scalp after the recording procedure, when compared to electrolytic gels. The electrochemical studies prove the proposed hydrogels to be applicable for bioelectric signal acquisition. Moreover, in-vivo EEG tests show no considerable differences between signals acquired with the hydrogel and the commercial electrolytic gel during the same signal acquisition, in terms of amplitude, signal shape, power spectral density and signal-to-noise ratio. In conclusion, the proposed hydrogels enhance the applicability and reliability of EEG by reducing gel running risks and simplifying the cleaning after the exam, as evidenced by the performed cleaning tests. © 2017 Elsevier B.V.

Comani S.,University of Chieti Pescara | Velluto L.,Casa di Cura Privata Villa Serena | Schinaia L.,Casa di Cura Privata Villa Serena | Schinaia L.,University of Chieti Pescara | And 6 more authors.
IEEE Transactions on Neural Systems and Rehabilitation Engineering | Year: 2015

A novel system for the neuro-motor rehabilitation of upper limbs was validated in three sub-acute post-stroke patients. The system permits synchronized cortical and kinematic measures by integrating high-resolution EEG, passive robotic device and Virtual Reality. The brain functional re-organization was monitored in association with motor patterns replicating activities of daily living (ADL). Patients underwent 13 rehabilitation sessions. At sessions 1, 7 and 13, clinical tests were administered to assess the level of motor impairment, and EEG was recorded during rehabilitation task execution. For each session and rehabilitation task, four kinematic indices of motor performance were calculated and compared with the outcome of clinical tests. Functional source maps were obtained from EEG data and projected on the real patients' anatomy (MRI data). Laterality indices were calculated for hemispheric dominance assessment. All patients showed increased participation in the rehabilitation process. Cortical activation changes during recovery were detected in relation to different motor patterns, hence verifying the system's suitability to add quantitative measures of motor performance and neural recovery to classical tests. We conclude that this system seems a promising tool for novel robot-based rehabilitation paradigms tailored to individual needs and neuro-motor responses of the patients. © 2001-2011 IEEE.

Comani S.,University of Chieti Pescara | Schinaia L.,Casa di Cura Privata Villa Serena | Tamburro G.,University of Chieti Pescara | Velluto L.,Casa di Cura Privata Villa Serena | And 3 more authors.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS | Year: 2015

One post-stroke patient underwent neuro-motor rehabilitation of one upper limb with a novel system combining a passive robotic device, Virtual Reality training applications and high resolution electroencephalography (HR-EEG). The outcome of the clinical tests and the evaluation of the kinematic parameters recorded with the robotic device concurred to highlight an improved motor recovery of the impaired limb despite the age of the patient, his compromised motor function, and the start of rehabilitation at the 3rd week post stroke. The time frequency and functional source analysis of the HR-EEG signals permitted to quantify the functional changes occurring in the brain in association with the rehabilitation motor tasks, and to highlight the recovery of the neuro-motor function. © 2015 IEEE.

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