Time filter

Source Type

Piacentini V.,Azienda Ospedaliera Polo Universitario cco | Mauri I.,Azienda Ospedaliera Polo Universitario cco | Cattaneo D.,Azienda Ospedaliera Polo Universitario cco | Gilardone M.,Casa di Cura Privata Del Policlinico | And 2 more authors.
Archives of Physical Medicine and Rehabilitation | Year: 2014

Objective To evaluate dysarthria and dysarthria-related quality of life (QOL) and analyze its relations with duration of disease, severity, and general QOL in patients with multiple sclerosis (MS).Design Cross-sectional observational study.Setting Rehabilitation center.Participantsg Consecutive patients with MS (N=163) were recruited (mean age, 52±10.4y; mean MS duration, 19±10.4y).Interventions Not applicable.Main Outcome Measures Presence of dysarthria; dysarthria characteristics; MS severity and duration; and dysarthria-related and generic QOL were evaluated by means of the therapy outcome measure scale; Robertson profile; Expanded Disability Status Scale (EDSS), years of disease; QOL of the dysarthric speaker questionnaire; and Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36), respectively.Results The mean EDSS score was 6.5±1.3. Dysarthria affected 57 (35%) of the 163 patients. Dysarthria severity was mild in most of the 57 patients with dysarthria. Median Robertson profile scores were slightly but significantly higher in the nondysarthric group compared with the dysarthric group (P=.001). The QOL for the dysarthric speaker questionnaire was significantly more compromised in patients with dysarthria (P=.001). No difference on the SF-36 scores between patients with and without dysarthria was found, with the exception of the physical activity and physical pain subscales. The QOL for the dysarthric speaker questionnaire showed no correlation with MS duration and a weak correlation with EDSS score (r=.25). Correlations between the SF-36 and QOL for the dysarthric speaker scores were few and weak, with the exception of the role limitations because of emotions (r=-.428) and mental health subscales (r=-.383).Conclusions Dysarthria-related QOL is compromised in patients with MS and dysarthria and might be used as a supplementary measure in clinical practice and research for patients who have MS. © 2014 American Congress of Rehabilitation Medicin.


Balconi M.,University of Milan | Sozzi M.,Casa di Cura Privata Del Policlinico | Ferrari C.,University of Milan | Pisani L.,Casa di Cura Privata Del Policlinico | And 2 more authors.
Cognitive Processing | Year: 2012

The present study explored beha"ioral and eye-mo"ement measures in unilateral neglect patients in response to online bisection task (unfilled gap line). Two different tasks supported the bisection performance, a pointing and a grasping strategy. It was explored whether these different strategies may influence subjects' beha"ioral and eye-mo"ement measures in response to different segment features: segment length (from shorter to longer) and segment spatial dislocation (from right to left spatial location). Consistent spatial biases were found for both bisection responses, fixation count, and duration, as well as for the first fixation count in case of pointing task. An "extreme-left" gradient effect was suggested and discussed, with patients' beha"ioral and eye measures more impaired. On the contrary, the patients' performance o"erlaps with the controls' one in case a grasping task. The direct link of "isual pointing and grasping strategy, respecti"ely, with the two cortical "entral and dorsal pathways was adduced to explain our results. © Marta Olivetti Belardinelli and Springer-Verlag 2012.


Sozzi M.,Casa di Cura Privata Del Policlinico | Balconi M.,Catholic University of the Sacred Heart | Arangio R.,Catholic University of the Sacred Heart | Pisani L.,Casa di Cura Privata Del Policlinico | And 2 more authors.
Cognitive Processing | Year: 2012

The aim of this work is to verify the effectiveness of our treatment in patients with spatial neglect in relation to their age and to the severity of neglect. Lots of studies on rehabilitation were proposed and, in some of them, treatments based upon visual-scanning abilities were described. Our rehabilitation training is aimed to induce patients to find by themselves an adequate strategy to solve spatial problems and, after that, try to let this searching strategy as automatized as possible. In this study, forty-six patients with right brain damage and left visuo-spatial neglect underwent to this specific cognitive treatment. A neuropsychological battery was administered before and after treatment. Repeated measure MANOVA on test performances showed significant main effects of treatments, age, and severity of neglect; an interaction effect between these three variables was found as well. Our results confirm an effectiveness of treatment, in particular for elderly patients. Actually, they seem to show a better recovery of neglect after cerebral stroke, even for those of them affected by a severe neglect. These data could be explained in accordance with recent neurophysiological models that claim compensatory responses to reduce brain plasticity even in terms of reorganization of cognitive functions such as visuo-spatial attention. © 2012 Marta Olivetti Belardinelli and Springer-Verlag.


Balconi M.,University of Milan | Amenta S.,University of Milan | Sozzi M.,Casa Di Cura Privata del Policlinico | Cannata A.P.,Casa Di Cura Privata del Policlinico | Pisani L.,Casa Di Cura Privata del Policlinico
Brain Injury | Year: 2013

Primary objective: The present study explored the behavioural and eye-movement measures in spatial unilateral neglect in response to a bisection task. Research design: Four right neglect patients were considered and compared with 11 control subjects during an online task (segment bisection). Methods and procedures: Eye-movements (fixation count and duration) and behavioural responses were monitored during an online bisection task, consisting of unfilled segments (two ending points) to be bisected by subjects. Segment length (six levels) and spatial dislocation (five levels) were modulated to explore a possible 'gradient effect'" (left-to-right) in neglect bias. Main outcomes and results: Consistent spatial biases were found for both bisection position and eye fixations as a function of segment length (from shorter to longer) and segment spatial dislocation (from right to left). However, only the more eccentric left-positions induced a greater rightward bias in patients, with increasing more right-side bisection and visual right-directed fixations. Also segment length produced significant differences between-groups for behavioural responses, with more right-side bisection for longer segment in patients, and eye movement behaviour, with increased fixation count and duration rightward oriented in response to longer segments. Conclusions: Although a left-to-right and longer-to-shorter 'continuous-gradient effect' was not supported by the results, an 'extreme left-gradient effect' was suggested and discussed. © 2013 Informa UK Ltd.


PubMed | Casa di Cura Privata del Policlinico
Type: | Journal: Cognitive processing | Year: 2012

The aim of this work is to verify the effectiveness of our treatment in patients with spatial neglect in relation to their age and to the severity of neglect. Lots of studies on rehabilitation were proposed and, in some of them, treatments based upon visual-scanning abilities were described. Our rehabilitation training is aimed to induce patients to find by themselves an adequate strategy to solve spatial problems and, after that, try to let this searching strategy as automatized as possible. In this study, forty-six patients with right brain damage and left visuo-spatial neglect underwent to this specific cognitive treatment. A neuropsychological battery was administered before and after treatment. Repeated measure MANOVA on test performances showed significant main effects of treatments, age, and severity of neglect; an interaction effect between these three variables was found as well. Our results confirm an effectiveness of treatment, in particular for elderly patients. Actually, they seem to show a better recovery of neglect after cerebral stroke, even for those of them affected by a severe neglect. These data could be explained in accordance with recent neurophysiological models that claim compensatory responses to reduce brain plasticity even in terms of reorganization of cognitive functions such as visuo-spatial attention.

Loading Casa di Cura Privata Del Policlinico collaborators
Loading Casa di Cura Privata Del Policlinico collaborators