CAS Zhengzhou Research Institute

Henan, China

CAS Zhengzhou Research Institute

Henan, China

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Wang L.,CAS Zhengzhou Research Institute | Li B.,CAS Zhengzhou Research Institute | Lu D.,CAS Zhengzhou Research Institute | Wang B.,CAS Zhengzhou Research Institute
Tobacco Science and Technology | Year: 2016

In order to investigate the dynamic ventilation characteristics of cigarette at different puff profiles, the pressure drop and total ventilation rate of an unlit 3R4F cigarette were measured at different puff profiles, a three dimensional mathematical model for air flowing in a cigarette was established. The model was validated via measuring the pressure drop and total ventilation rate of 3R4F cigarette during smoking at a constant velocity of 17.5 mL/s. It was found that the relative errors of both measured values and simulated values were less than 1.5%. The three dimensional and axial distributions of pressure drop and flow rate in 3R4F cigarette at either a constant draw velocity or ISO puff profile were analyzed by the established model. The results showed that at a constant draw velocity, the velocity of air entering into 3R4F cigarette was in positive proportion to its distance to the mouth end; under ISO puffing mode, the pressure drop of 3R4F was in positive proportion to puffing flow rate, while the total ventilation rate of cigarette had nothing to do with puffing flow rate and remained constant. © 2016, Editorial Office of Tobacco Science and Technology. All right reserved.

Liu Q.-B.,Nanjing Forestry University | Niu J.-J.,CAS Zhengzhou Research Institute
Inorganic Chemistry Communications | Year: 2013

A new compound, namely [Zn1.5(pbdc)(ATAZ)(OH)]n (1 H2pbdc = terephthalic acid, HATAZ = 3-amino-1,2,4-triazole), has been obtained by in situ aminotriazole ligand synthesis and characterized by elemental analysis, thermal analysis, as well as single crystal and powder X-ray diffraction analysis. Compound 1 exhibits a 3D pillar-layer framework based on Zn(II)-aminotriazole layers and pbdc pillars, which can be simplified into a 2-fold interpenetrated pcu topological network. Interestingly, two ATAZ ligands and two OH- ligands bridge three Zn(II) ions together, giving rise to a new trinuclear {Zn3(ATAZ)2(OH)2} subunit. In addition, the luminescent and thermal stability properties for the title compound have also been studied. © 2013 Elsevier B.V.

Zhang X.,CAS Zhengzhou Research Institute
Modern Tunnelling Technology | Year: 2014

In view of the current status of few researches on the fire damage assessment of lining and few guiding specifications, this paper used indexes like apparent damage characteristics, damage depth, residual strength and sound velocity ratios of concrete, etc to analyze fire damage to certain expressway tunnel lining and relevant reinforcement measures. The results show that: qualitative or quantitative assessment of fire damage to lining can be carried out by adopting one or more indexes because of their dependency and consistency. ©, 2015, Editorial Office of "Modern Tunnelling Technology". All right reserved.

Liu J.,CAS Zhengzhou Research Institute
Advanced Materials Research | Year: 2014

As a new type of ecology treatment technology, constructed wetland has been widely utilized in the sewage disposal system. The paper researches into the constructed wetland's basic concept, structural constitutions and the sewage disposal mechanism. It has been certified that the constructed wetland technology play an important role in decreasing point source pollution on expressway. © (2014) Trans Tech Publications, Switzerland.

Niu J.-J.,CAS Zhengzhou Research Institute | Li D.,CAS Zhengzhou Research Institute
Inorganic Chemistry Communications | Year: 2014

A new Mn(II) compound, namely [Mn3(OABDC)2(H 2O)4]n (1 H3OABDC = 5-oxyacetateisophthalic acid), has been synthesized through combination of H3OABDC and MnCl2 under solvothermal conditions. A single crystal X-ray analysis reveals that 1 is a complicated three-dimensional (3D) framework based on trinuclear [Mn3(COO)4] subunits, which can be simplified into a (3, 6)-connected ant network. Variable temperature magnetic investigation reveals that this compound exhibits antiferromagnetic behavior. © 2013 Elsevier B.V.

Wang Y.,CAS Institute of Chemistry | Wang X.,CAS Zhengzhou Research Institute | Guo Z.,CAS Institute of Chemistry | Chen Y.,CAS Institute of Chemistry | Chen Y.,CAS Beijing National Laboratory for Molecular
Talanta | Year: 2014

Graphene's unsurpassed specific surface area (up to 2630 m2/g) makes it be an ideal absorbent. To promote its use as a sorption coating in solid phase microextraction, an ultrafast method was established, able to coat a stable layer of graphene on a metal fiber in only 23 s, with adjustable coating thickness between 10 and 40 μm by using sleeve barrels. The core idea includes: (1) use of semi-polymerized dimethylsiloxane as a sticky pre-liner to glue graphene and (2) rapid conversion from pre-liner to elastic polydimethylsiloxane (PDMS) to fix the glued graphene. Ultrafast conversion of the pre-liner to PDMS was achieved by direct heating of the metallic fibers. The method produced very stable and durable fibers, capable of being used for at least 120 extractions-desorption cycles and stored at room temperature for at least 20 months. Interestingly, the new method could always coat a layer of mossy graphene on the fibers to largely increase their extraction capacity. Their limit of detection reached 2 pg/L PAHs, being about 3 orders of magnitude better than that of the reported graphene-based fibers. They were applicable to the direct extraction of trace PAHs in beverages, with a linear regression range from 10 to 1000 pg/L, and recoveries of 88.9-105.3%. The relative standard deviations of peak area were 2.9-8.9% for the same fiber and 3.0-10.0% for different fibers. The method is also suitable for re-coating a used fiber and extendable to fast coating other solid sorbents on heat-resistant supports. © 2013 Elsevier B.V.

Li C.M.,CAS Zhengzhou Research Institute
Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji | Year: 2011

We identified and characterized a Chinese family with autosomal dominant Brachydactyly type B1 (BDB1). Linkage analysis revealed that the disease gene of the Chinese BDB1 family was linked to ROR2 locus. Mutational hot spot of ROR2 gene was amplified by polymerase chain reaction (PCR) and sequenced directly. A c.2265C>A heterozygous mutation was detected in all of the patients. This mutation led to the change of p.Y755X in protein level and a truncated ROR2 protein losing integrant domains was generated. The mutation was detected in all the patients, but not in all the normal individuals of this family and 50 normal controls. This paper for the first time reported a c.2265C>A mutation in ROR2 gene of a family with BDB1 in China, which enriches ROR2 gene mutation spectrum in Chinese with BDB1.

Lu J.,Zhejiang University | Cao H.,Zhejiang University | Zhang L.,Zhejiang University | Huang P.,Zhejiang University | And 2 more authors.
PLoS Pathogens | Year: 2014

Because of great challenges and workload in deleting genes on a large scale, the functions of most genes in pathogenic fungi are still unclear. In this study, we developed a high-throughput gene knockout system using a novel yeast-Escherichia-Agrobacterium shuttle vector, pKO1B, in the rice blast fungus Magnaporthe oryzae. Using this method, we deleted 104 fungal-specific Zn2Cys6 transcription factor (TF) genes in M. oryzae. We then analyzed the phenotypes of these mutants with regard to growth, asexual and infection-related development, pathogenesis, and 9 abiotic stresses. The resulting data provide new insights into how this rice pathogen of global significance regulates important traits in the infection cycle through Zn2Cys6TF genes. A large variation in biological functions of Zn2Cys6TF genes was observed under the conditions tested. Sixty-one of 104 Zn2Cys6 TF genes were found to be required for fungal development. In-depth analysis of TF genes revealed that TF genes involved in pathogenicity frequently tend to function in multiple development stages, and disclosed many highly conserved but unidentified functional TF genes of importance in the fungal kingdom. We further found that the virulence-required TF genes GPF1 and CNF2 have similar regulation mechanisms in the gene expression involved in pathogenicity. These experimental validations clearly demonstrated the value of a high-throughput gene knockout system in understanding the biological functions of genes on a genome scale in fungi, and provided a solid foundation for elucidating the gene expression network that regulates the development and pathogenicity of M. oryzae. © 2014 Lu et al.

Zhang W.,Hefei University of Technology | Zhang W.,CAS Zhengzhou Research Institute | Chen B.,Hefei University of Technology | Yu N.,Hefei University of Technology
IEEE Transactions on Image Processing | Year: 2012

In reversible data hiding (RDH), the original cover can be losslessly restored after the embedded information is extracted. Kalker and Willems established a rate-distortion model for RDH, in which they proved out the rate-distortion bound and proposed a recursive code construction. In our previous paper, we improved the recursive construction to approach the rate-distortion bound. In this paper, we generalize the method in our previous paper using a decompression algorithm as the coding scheme for embedding data and prove that the generalized codes can reach the rate-distortion bound as long as the compression algorithm reaches entropy. By the proposed binary codes, we improve three RDH schemes that use binary feature sequence as covers, i.e., an RS scheme for spatial images, one scheme for JPEG images, and a pattern substitution scheme for binary images. The experimental results show that the novel codes can significantly reduce the embedding distortion. Furthermore, by modifying the histogram shift (HS) manner, we also apply this coding method to one scheme that uses HS, showing that the proposed codes can be also exploited to improve integer-operation-based schemes. © 2012 IEEE.

Li X.,CAS Zhengzhou Research Institute
Toxicology in Vitro | Year: 2016

Cigarette smoke is a complex aerosol comprising particulate phase and gaseous vapour phase. The air-liquid interface exposure provides a possible technical means to implement whole smoke exposure for the assessment of tobacco products. In this review, the research progress in the in vitro toxicity testing of cigarette smoke based on the air-liquid interface exposure is summarized. The contents presented involve mainly cytotoxicity, genotoxicity, oxidative stress, inflammation, systems toxicology, 3D culture and cigarette smoke dosimetry related to cigarette smoke, as well as the assessment of electronic cigarette aerosol. Prospect of the application of the air-liquid interface exposure method in assessing the biological effects of tobacco smoke is discussed. © 2016

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