Carnegie Mellon University is a private research university in Pittsburgh, Pennsylvania.The university began as the Carnegie Technical Schools founded by Andrew Carnegie in 1900. In 1912, the school became the Carnegie Institute of Technology and began granting four-year degrees. In 1967, the Carnegie Institute of Technology merged with the Mellon Institute of Industrial Research to form Carnegie Mellon University. The university's 140-acre main campus is 3 miles from Downtown Pittsburgh and abuts the Carnegie Museums of Pittsburgh, the main branch of the Carnegie Library of Pittsburgh, the Carnegie Music Hall, Schenley Park, Phipps Conservatory and Botanical Gardens, the Pittsburgh Golf Club, and the campus of the University of Pittsburgh in the city's Oakland and Squirrel Hill neighborhoods, partially extending into Shadyside.Carnegie Mellon has seven colleges and independent schools: the Carnegie Institute of Technology , College of Fine Arts, Dietrich College of Humanities and Social science, Mellon College of Science, Tepper School of Business, H. John Heinz III College and the School of Computer Science. Carnegie Mellon fields 17 varsity athletic teams as part of the University Athletic Association conference of the NCAA Division III. Wikipedia.
Carnegie Mellon University | Date: 2016-07-28
Provided herein are methods of suppressing viral nucleic acid, e.g. double-stranded (ds) DNA, genome release from or packaging of viruses having their nucleic acid genome packaged under stress in their capsid, and compositions useful for that purpose. The methods alter the ionic environment of the nucleic acid within the capsid and thereby prevent release of, and/or interfere with packaging of the viral genome.
Carnegie Mellon University | Date: 2016-09-19
The disclosure describes a prism containing a microfluidic channel. By coupling bulk acoustic wave generators to opposing sides of the prism, a standing bulk acoustic wave field can be excited in the prism and in the microfluidic channel. Because the microfluidic channel is titled with respect to the nodes of the bulk acoustic wave field, the prism microfluidic channel device can be used to separate microparticles and biological cells by size, compressibility, density, shape, or mass distribution. This technology enables high throughput cell sorting for biotechnology applications such as cancer cell detection.
Carnegie Mellon University | Date: 2015-05-08
A method of making optically pure preparations of chiral PNA (gamma peptide nucleic acid) monomers is provided. Nano structures comprising chiral PNA structures also are provided. Methods of amplifying and detecting specific nucleic acids, including in situ methods are provided as well as compositions and kits useful in those methods. Lastly, methods of converting nucleobase sequences from right-handed helical PNA, nucleic acid and nucleic acid analog structures to left-handed PNA, and vice-versa, are provided.
Carnegie Mellon University | Date: 2015-06-17
Identifying a masked suspect is one of the toughest challenges in biometrics that exist. This is an important problem faced in many law-enforcement applications on almost a daily basis. In such situations, investigators often only have access to the periocular region of a suspects face and, unfortunately, conventional commercial matchers are unable to process these images in such a way that the suspect can be identified. Herein, a practical method to hallucinate a full frontal face given only a periocular region of a face is presented. This approach reconstructs the entire frontal face based on an image of an individuals periocular region. By using an approach based on a modified sparsifying dictionary learning algorithm, faces can be effectively reconstructed more accurately than with conventional methods. Further, various methods presented herein are open set, and thus can reconstruct faces even if the algorithms are not specifically trained using those faces.
Carnegie Mellon University | Date: 2017-02-01
An articulated probe (10), comprising: a first mechanism (12, 14) comprised of a plurality of links; a second mechanism (12, 14) comprised of a plurality of links; a first wire extending through either said plurality of links of said first mechanism (12, 14) or said plurality of links of said second mechanism (12, 14) and a plurality of wires running through the other of said plurality of links of said first mechanism (12, 14) or said plurality of links of said second mechanism (12, 14); a device for producing command signals; and an electromechanical feeder (16) responsive to said command signals, said electromechanical feeder (16) capable of alternating each of said first mechanism (12) and second mechanism (14) between a limp mode and a rigid mode and comprising: a first motor for controlling the tension of said first wire or said plurality of wires, one of said first mechanism or said second mechanism being responsive to said first motor; and a second motor for controlling the tension of the other of said first wire or said plurality of wires, the other of said first mechanism or said second mechanism being responsive to said second motor and a method of moving the articulated probe.
Carnegie Mellon University and Deere & Company | Date: 2017-04-26
Disclosed herein is a system (11) for evaluating agricultural material which comprises, in one embodiment, a housing (102) having a passage (104) in or through an interior (106) of the housing (102) with an inlet (108) for receiving agricultural material and an outlet (110) for outputting the agricultural material. The system further comprises a wall opening (112) in a wall (109) of the passage. An imaging device (116) having a lens (118) is located inward from a border (120) of the imaging device. The imaging device (116) is pivotally mounted for rotation with respect to a housing (102) such that in a closed state the border (120) of the imaging device rests on, engages or interlocks the wall opening (112) of the housing (102), and in an open state the border (120) exposes the wall opening (112) and an interior (106) of the housing (102).
Carnegie Mellon University and Deere & Company | Date: 2017-04-26
Disclosed herein is a diagnostic module configured to determine an average image of a set or a sequence of collected images, to obtain a last image of the set or the sequence of collected images, and to determine a difference between the average image and the last image to yield a differenced image. Background image data or background pixels are eliminated from the differenced image to produce an initial image mask of unchanged content in the last image. A diagnostic module or data processor determines a mask area of the initial image mask or a revised image mask derived from the initial image mask. A diagnostic module or data processor generates an alert data message to inspect or clean the imaging system if the mask area exceeds a threshold area.
Carnegie Mellon University | Date: 2016-12-14
Methods for conducting controlled grafting-from radical polymerizations from biomolecules under conditions that are biologically compatible are described. The methods provide biomolecule-polymer conjugates with highly controlled structures and narrow polydispersities under aqueous reaction conditions and biological temperatures. Biomolecules, such as proteins and nucleotides can be conjugated to polymers with high levels of control.
Carnegie Mellon University | Date: 2017-02-10
Local swing leg control was developed that takes advantage of segment interactions to achieve robust leg placement under large disturbances while generating trajectories and joint torque patterns similar to those observed in human walking and running. The results suggest the identified control as a powerful alternative to existing swing leg controls in humanoid and rehabilitation robotics. Alternatively, a detailed neuromuscular model of the human swing leg was developed to embody the control with local muscle reflexes. The resulting reflex control robustly places the swing leg into a wide range of landing points observed in human walking and running, and it generates similar patterns of joint torques and muscle activations. The results suggest an alternative to existing swing leg controls in humanoid and rehabilitation robotics which does not require central processing.
Matyjaszewski K.,Carnegie Mellon University
Macromolecules | Year: 2012
Current status and future perspectives in atom transfer radical polymerization (ATRP) are presented. Special emphasis is placed on mechanistic understanding of ATRP, recent synthetic and process development, and new controlled polymer architectures enabled by ATRP. New hybrid materials based on organic/inorganic systems and natural/synthetic polymers are presented. Some current and forthcoming applications are described. © 2012 American Chemical Society.