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Enugu, Nigeria

Caritas University is a private Catholic university in Amorji-Nike, Enugu State, Nigeria. Enjoying both state and ecclesiastical approval, it strives to revive in its community the age-long tradition of Catholic education and the exacting demand of contemporary society for sound education rooted in salubrious life-promoting morality. Wikipedia.

Siryani I.,Caritas University | Jama M.,Arup | Rumman N.,Caritas Baby Hospital | Marzouqa H.,Caritas Baby Hospital | And 4 more authors.
PLoS ONE | Year: 2015

Cystic fibrosis (CF) is an autosomal recessive inherited life-threatening disorder that causes severe damage to the lungs and the digestive system. In Palestine, mutations in the Cystic Fibrosis Transmembrane Conductance Regulator gene (CFTR) that contributes to the clinical presentation of CF are ill defined. A cohort of thirty three clinically diagnosed CF patients from twenty one different Palestinian families residing in the central and southern part of Palestine were incorporated in this study. Sweat chloride testing was performed using the Sweat Chek Conductivity Analyzer (ELITECH Group, France) to confirm the clinical diagnosis of CF. In addition, nucleic acid from the patients' blood samples was extracted and the CFTR mutation profiles were assessed by direct sequencing of the CFTR 27 exons and the intron-exon boundaries. For patient's DNA samples where no homozygous or two heterozygous CFTR mutations were identified by exon sequencing, DNA samples were tested for deletions or duplications using SALSA MLPA probemix P091-D1 CFTR assay. Sweat chloride testing confirmed the clinical diagnosis of CF in those patients. All patients had NaCl conductivity >60mmol/l. In addition, nine different CFTR mutations were identified in all 21 different families evaluated. These mutations were c.1393-1G>A, F508del, W1282X, G85E, c.313delA, N1303K, deletion exons 17a-17b-18, deletion exons 17a-17b and Q1100P. c.1393-1G>A was shown to be the most frequent occurring mutation among tested families. We have profiled the underling mutations in the CFTR gene of a cohort of 21 different families affected by CF. Unlike other studies from the Arab countries where F508del was reported to be the most common mutation, in southern/ central Palestine, the c.1393-1G>A appeared to be the most common. Further studies are needed per sample size and geographic distribution to account for other possible CFTR genetic alterations and their frequencies. Genotype/phenotype assessments are also recommended and finally carrier frequency should be ascertained. © 2015 Siryani et al. Source

Nnaji N.J.N.,Caritas University | Ani J.U.,University of Nigeria | Aneke L.E.,University of Nigeria | Onukwuli O.D.,Nnamdi Azikiwe University | And 2 more authors.
Journal of Industrial and Engineering Chemistry | Year: 2014

The coagulant behaviour of tannins of Anacardium occidentale (CANTETA) testa was assessed for the removal of suspended solids from a fibre-cement industry effluent. A series of flocculation experiments were conducted to examine the optimal concentration of the coagulant together with the pH of the effluent needed to obtain the best results. The results showed that CANTETA have significant flocculation properties particularly at lower doses and in alkaline medium. Optimum efficiency for TSS removal was 84% with 100. mg/L CANTETA at initial effluent pH of 12. The kinetics of the coagulation process suitably fits the second order kinetic model. © 2013 The Korean Society of Industrial and Engineering Chemistry. Source

Nwadiogb J.O.,Caritas University | Igwe A.A.,University of Nigeria | Okoye N.H.,Nnamdi Azikiwe University | Chime C.C.,Enugu State University of Science and Technology
Der Pharma Chemica | Year: 2015

In this work, the compositional characteristics of mango kernel (MK) were established in terms of lignin, cellulose and hemicelluloses contents, to access its suitability for the extraction of microfibrils. Cellulose amounting to (25.2 %), hemicelluloses (34.06 %), lignin (15 %) were extracted. Microcrystalline cellulose (MCC) was extracted by hydrochloric acid hydrolysis of a-cellulose derived from the MK. The morphology of the MK-MCC was investigated using scanning electron microscope (SEM), and showed a compact structure and rough surface. X-ray diffraction (XRD) analysis showed that the MCC produced is of cellulose-1 polymorph, with 50.3% crystallinity. The physicochemical properties of the MCC suggests that the cellulose has good flow and compression properties, hence suitable for a range of applications such as green biodegradable nanocomposites reinforced with this form of cellulose and pharmaceutical tabletting. Source

Nwamaka N.T.,University of Nigeria | Chike A.E.,Caritas University
African Journal of Microbiology Research | Year: 2010

The demand for fermented dairies is on the increase in developing countries following consumer awareness of some of the health benefits attributed to prolonged intake. Eight samples of yoghurt produced from Enugu, Eastern Nigeria was collected from various locations. Samples were incubated using various media for the isolation, identification and enumeration of the bacteria population within the yoghurt. Reports indicated that total viable count of bacteria was in the range of 1.4 x 106 - 2.2 x 107 cfu /ml. Not all bacterial isolates were lactose fermenters. Members of the genus Staphylococcus, Aeromonas, Klebsiella, Pseudomonas, Bacillus, Streptococcus and Lactobacillus were isolated with 100, 25, 50, 33.3, 25, 12.5 and 25% frequency of occurrence, respectively. Viable counts of lactic acid bacteria were low indicating that probiotics effect following consumption may be poor. Occurrence of pathogenic organisms indicates improper handling and inadequate sanitary measures. More care should be taken during yoghurt fermentation. © 2010 Academic Journals. Source

Nnaemeka-Okeke R.,Caritas University
Journal of Ecological Engineering | Year: 2016

Urban environmental problems are of different dimensions and are mostly due to geologic, climatic and cultural factors. However, the cultural factors seems to be more pronounced in the Nigerian context because most of the identified urban environmental issues are so much associated with the way of life of the people, either as reactions to urbanization or their spatial heritage. Their effects are far reaching on efforts to attain sustainable development in the country. Since no section of the country's urban environment is immune to environmental effects, there is urgent need to seek workable solutions by the application of planning, economic, legal, institutional and educational tools as have been suggested here. Source

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