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Funtikova A.,Cardiovascular Risk and Nutrition Research Group CARIN ULEC | Koebnick C.,Kaiser Permanente | Gomez S.F.,Cardiovascular Risk and Nutrition Research Group CARIN ULEC | Covas M.-I.,Cardiovascular Risk and Nutrition Research Group CARIN ULEC | And 4 more authors.
European Journal of Clinical Nutrition

Coronary heart disease prevention in the primary care setting, where time is extremely limited, requires valid instruments that efficiently screen for unhealthy lifestyle habits. Identification of the individuals who would most benefit from dietary in tervention is particularly important in this context. We used dietary intake data derived from a full-length food frequency questionnaire to simulate responses to our previously validated short dietary quality screener. We determined the prospective association of the resulting diet-quality index (DQI) with changes in anthropometric and cardiometabolic risk variables in 2181 men and women in a 10-year follow-up. Multiple linear regression analyses revealed that a higher DQI score at baseline related directly (P=0.002) to high-density lipoprotein cholesterol (HDL-C) and inversely (P0.016) to waist circumference (WC), triacylglycerides (TG), the TG to HDL-C ratio and the total cholesterol to HDL-C ratio at follow-up. A low DQI score is predictive for an increase in WC and the development of an unfavourable cardiometabolic profile. © 2012 Macmillan Publishers Limited. Source

Benitez-Arciniega A.A.,Cardiovascular Risk and Nutrition Research Group CARIN ULEC | Benitez-Arciniega A.A.,CIBER ISCIII | Benitez-Arciniega A.A.,Program of Research in Inflammatory and Cardiovascular Disorders | Mendez M.A.,Center for Research in Environmental Epidemiology | And 15 more authors.
Public Health Nutrition

Objective The aim of the present study was to assess the concurrent and construct validity of two diet-quality indices, a modified Mediterranean diet score (mMDS) and a Mediterranean-like diet score (MLDS) additionally incorporating unhealthy food choices, as determined by an FFQ. Design A validation study assessing FFQ intake estimates compared with ten or more unannounced 24 h recalls. Pearson's correlation coefficients, intraclass correlation coefficients (ICC), Bland-Altman plots and the limits of agreement method were used to assess the between-method agreement of scores. Construct validity was shown using associations between nutrient intakes derived from multiple 24 h recalls and the mMDS and MLDS derived from the FFQ. Setting Gerona, Spain. Subjects A total of 107 consecutively selected participants from a population-based cross-sectional survey. Results Pearson's correlations for the energy-adjusted mMDS and MLDS compared with multiple recalls were 0.48 and 0.62, respectively. The average FFQ energy-adjusted mMDS and MLDS were 102 % and 98 % of the recall-based mMDS and MLDS estimates, respectively. The FFQ under- and overestimated dietary recall estimates of the energy-adjusted MLDS by 28 % and 25 %, respectively, with slightly wider boundaries for the mMDS (31 % and 34 %). The ICC, which assesses absolute agreement, was similar to Pearson's correlations (mMDS = 0.48 and MLDS = 0.61). The mean differences between methods were similar across the range of average ratings for both scores, indicating the absence of bias. The FFQ-derived mMDS and MLDS correlated in the anticipated directions with intakes of eleven (73.3 %) and thirteen of fifteen nutrients (86.7 %), respectively.Conclusions The FFQ provides valid estimates of diet quality as assessed by the mMDS and MLDS. © 2011 The Authors. Source

Goday A.,Hospital Del Mar | Goday A.,Cardiovascular Risk and Nutrition Research Group CARIN ULEC | Goday A.,CIBER ISCIII | Goday A.,Autonomous University of Barcelona | And 25 more authors.
Surgery for Obesity and Related Diseases

Background: Bariatric surgery has been shown to be effective in resolving co-morbid conditions even in patients with a body mass index (BMI) < 35 kg/m2. A question arises regarding the metabolic benefits of bariatric surgery in metabolically healthy but morbidly obese (MHMO) patients, characterized by a low cardiometabolic risk. The objective of this study was to assess the effects of bariatric surgery on cardiometabolic risk factors among MHMO and metabolically unhealthy morbidly obese (MUMO) adults. Methods: A nonrandomized, prospective cohort study was conducted on 222 severely obese patients (BMI > 40 kg/m2) undergoing either laparoscopic roux-en-Y gastric bypass or laparo-scopic sleeve gastrectomy. Patients were classified as MHMO if only 1 or no cardiometabolic factors were present: high blood pressure, triglycerides, blood glucose (or use of medication for any of these conditions), decreased high-density lipoprotein-cholesterol (HDL-C) levels, and insulin resistance defined as homeostasis model assessment for insulin-resistance (HOMA-IR) > 3.29. Results: Forty-two (18.9%) patients fulfilled the criteria for MHMO. They were younger and more frequently female than MUMO patients. No differences between groups were observed for weight, BMI, waist and hip circumference, total and LDL-C. MHMO patients showed a significant decrease in blood pressure, plasma glucose, HOMA-IR, total cholesterol, LDL-C and triglycerides and an increase in HDL-C 1 year after bariatric surgery. Weight loss 1 year after bariatric surgery was similar in both groups. Conclusion: Eighteen percent of patients with morbid obesity fulfilled the criteria for MHMO. Although cardiovascular risk factors in these patients were within normal range, an improvement in all these factors was observed 1 year after bariatric surgery. Thus, from a metabolic point of view, MHMO patients benefited from bariatric surgery. © 2014 American Society for Metabolic and Bariatric Surgery. All rights reserved. Source

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