CapitalBio Corporation and Tsinghua University | Date: 2014-07-24
In some aspects, the present disclosure provides a magnetic rack comprising a lateral movement structure and/or a longitudinal movement structure. In particular embodiments, the lateral movement structure and/or longitudinal movement structure move one or more magnets to or away from a reaction tube, in order to control the magnetic forces exerted on microbeads in the reaction tube. The microbeads are attracted onto the reaction tube wall, thereby facilitating separation of the microbeads from a solution in the tube. In particular embodiments, the magnetic rack is used to extract or purify nucleic acid from a sample.
CapitalBio Corporation and Tsinghua University | Date: 2013-05-07
In one aspect, a microfluidic device for multiple reactions is provided, which comprises a reaction channel comprising multiple reaction chambers connected to a closed chamber or an elastic balloon outside of the microfluidic device, wherein a wall of the closed chamber is an elastic membrane; and a control channel comprising an elastic side wall, wherein the intersections between the side wall of the control channel with the reaction channel form multiple pneumatic microvalves. In another aspect, a method for conducting multiple reactions using the microfluidic device is provided, which comprises: a) filling the reaction chambers with a sample; and b) applying pressure to the control channel to expand the elastic side wall of the control channel, wherein the expanded elastic side wall forms a pneumatic microvalve that separates the reaction chambers.
Tsinghua University and CapitalBio Corporation | Date: 2012-06-01
The present invention provides a microfluidic device and its use for cell motility classification. The microfluidic device comprises a fluid inlet, a sample inlet and a channel connecting the fluid inlet and the sample inlet, wherein the channel comprises at least two sections of different sizes, and the channel allows fluid flow from the fluid inlet to the sample inlet.
Tsinghua University and CapitalBio Corporation | Date: 2013-11-06
The present disclosure provides a cover sheet for a microarray reaction device. In one aspect, the present cover sheet or device ensures the reaction units/volumes are stable and/or consistent among assay samples and assay runs, allowing samples (e.g., reaction solutions) to be conveniently added and distributed uniformly.
Capitalbio Corporation and Tsinghua University | Date: 2013-11-01
Provided herein are methods, devices, and systems of wireless communication. In one embodiment, a method for wireless communication between a first electronic device and a second electronic device includes: providing information symbols to the first electronic device, transmitting a pairing request from the first electronic device to the second electronic device, obtaining a pairing password by accessing a database, and establishing a wireless communication channel between the first electronic device and the second electronic device. In some embodiments, the information symbols are provided audibly or visually by the second electronic device and include a wireless communication address of the second electronic device. In some embodiments, the pairing pass word is obtained using the wireless communication address. In some embodiments, the wireless communication channel is obtained using the obtained pairing password.