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Yu W.,Capital Institute of Physical Education | Su F.,Beijing Normal University
Proceedings - International Conference on Electrical and Control Engineering, ICECE 2010 | Year: 2010

Course of algorithm is a specialized course of computer science with both strong abstract nature and practicality, for which needs of algorithm visualization technique in CAI is prominent. This paper develops a visualized CAI aiming at the characteristics of the course of algorithm, which provides users with the functions like responding, changing, constructing and presenting, conforming to the engagement taxonomy defined by working group on "Improving the Educational Impact of Algorithm Visualization". © 2010 IEEE.


Ma Y.-Y.,Peking University | Zhang X.-L.,Capital Institute of Physical Education | Wu T.-F.,Peking University | Liu Y.-P.,Peking University | And 5 more authors.
Journal of Child Neurology | Year: 2011

Mitochondrial oxidative phosphorylation defects are a common cause of mitochondrial diseases, which are characterized by multiorgan involvement and clinically heterogeneous manifestations. Diagnosis is difficult because of the lack of clinically feasible methods. In this study, mitochondrial complex I-V enzyme activity was measured in 64 patients with suspected mitochondrial disease and 200 healthy controls. Spectrophotometric assay was used for the analysis of mitochondrial complex I-V enzyme activity in peripheral leukocytes. Diagnosis was based on clinical presentation, magnetic resonance imaging (MRI), muscle pathology, and point mutation screening in mitochondrial DNA. The differential diagnosis of aminoacidopathies, organic acidurias, and fatty acid -oxidation defects was made. Thirty-five patients (54.7%) were diagnosed with Leigh syndrome based on characteristic brain MRI. Complex enzyme activity in controls was found to be stable. A deficiency in the oxidative phosphorylation was found in 29 patients (45.3%). Twenty (31.2%) patients had isolated complex defects, complex I deficiency (n = 2, 3.1%), complex II deficiency (n = 3, 4.7%), complex III deficiency (n = 5, 7.8%), complex IV deficiency (n = 5, 7.8%), and complex V deficiency (n = 5, 7.8%). Nine patients were found to have combined deficiencies, 3 (4.7%) had combined deficiencies of complex I and IV, 2 (3.1%) had combined deficiencies of complex III and V, and 2 (3.1%) had a combined deficiency of complex I and V. In conclusion, the peripheral leukocyte oxidative phosphorylation enzyme activity assay was found to be a reliable method for the diagnosis of mitochondrial diseases. © 2011 The Author(s).


Zhu W.,Capital Institute of Physical Education | Zeng J.,Guangdong Provincial Hospital of Traditional Chinese Medicine | Yin J.,Capital Institute of Physical Education | Zhang F.,Capital Institute of Physical Education | And 3 more authors.
European Journal of Applied Physiology | Year: 2010

Obesity is associated with impaired endothelial function assessed as flow-mediated vasodilation (FMD), the procedure of which involves transient brachial artery occlusion and following reactive hyperemia. Acute aerobic exercise can improve FMD. This study examined the effects of repeated FMD procedures and acute aerobic exercise on FMD in obese young men. Upper arm cuff inflation of 200 mmHg for 5 min and subsequent deflation was induced at 0, 1 and 2 h to examine effects of repeated FMD procedures on FMD in obese subjects, as well as in lean controls. To observe the combined effects of FMD procedures and acute exercise on FMD in obese subjects, 45 min moderate exercise was performed immediately after FMD procedure at 0 h, with the procedure repeated at 1 and 2 h. The results showed that, after repeated FMD procedures, FMD in obese subjects increased from 5.9 ± 4.0% to 6.5 ± 3.2% and 8.4 ± 2.8% (P = 0.017), whereas FMD demonstrated no changes in lean controls (P = 0.90). After repeated FMD procedures and exercise, FMD in the obese subjects increased from 7.3 ± 3.5% to 9.5 ± 4.0% and 11.0 ± 4.3% (P = 0.0004). The present findings demonstrate that both repeated FMD procedures and acute aerobic exercise improve FMD in obese subjects. © 2009 Springer-Verlag.


Yu R.,Capital Institute of Physical Education | Ma S.,China Pharmaceutical University | Wu H.,Capital Institute of Physical Education
Advanced Materials Research | Year: 2014

The main purpose of this study was to examine the effects of polysaccharides from Ganoderma lucidum (GLP) supplementation on exhaustive exercise-induced apoptosis in mice liver. The mice were randomly divided into four groups of ten per group. One of the groups was the control group, the others were GLP treated groups (25, 50 and 100 mg/kg body weight). Exhaustive swimming exercise of mice were carried out after 28 days of GLP administration, and the expression of Bcl-2 and Bax proteins in the liver tissues were determined. The data showed that GLP supplementation was able to up-regulate the expression of Bcl-2 proteins and Bcl-2/Bax ratio, down-regulate the expression of Bax proteins. The results suggest that GLP supplementation prevents exhaustive exercise-induced apoptosis. © (2014) Trans Tech Publications, Switzerland.


Chen C.,Capital Institute of Physical Education | Wang Y.,Capital Institute of Physical Education
Chinese Journal of Rehabilitation Medicine | Year: 2016

Objective: To investigate the relationship between body balance and cognition function of sports college male students in different majors by evaluating their body balance ability and cognition function. Method: Forty eight college students from the majors of sports training, sports dance, Chinese traditional dance and kinesiology were recruited. All subjects understood the purpose of this experiment and agreed to participate in the experiment and had to complete the following experimental procedures. Firstly, they were tested by a body composition analyzer for their body composition information, including height, weight, body type, body mass index(BMI) and other indicators. Then they were tested for their static postural balance by using a system for stabalometric analysis (Postural Equa, Elettronica Pagani Co., Italy). All subjects were with opening eyes and closing eyes situations, for lasting 10s, respectively. Tested parameters of static postural balance included center of pressure (COP), total length of swinging pathway (TL), maximal length of swinging pathway (ML), area of swinging pathway (Area), lengch of stekokinesigram(LFS), distributions of pressure (DistrP). Finally they were tested for their simple reaction time and spatial positional memory span by PsyKey psychological system. Result: The results of body balance showed that, there was no significant difference of body balance in all majors of students between opening eyes and closing eyes situations (P>0.05). However, compared with closing eyes situations, all majors of students showed increased TL (P<0.01), ML (P<0.05) and area (P<0.01). The results of cognition showed that, the simple reaction time of sports training students was significantly shorter than that in Chinese traditional dance students (P<0.01) and sports dance students (P<0.05). The simple reaction time of kinesiology students was significantly shorter than that of Chinese traditional dance students (P<0.01). But there was no significant difference of spatial positional memory span in all majors of students (P> 0.05). For the relationship between body balance and cognition, the simple reaction time showed significant linear correlation with the area of swinging pathway in closing eyes situations (r=0.341, P<0.05). However, the spatial positional memory span had no correlation with any body balance parameters (P>0.05). Conclusion: These results suggest that balance ability is associated positively with cognition function in college male students, including the linear correlation between simple reaction time and the area of swinging pathway in closing eyes situations. The effect of different sports majors on correlation between body balance ability and cognition function in sports college students needs to be further studied. © 2016, Editorial Board of Chinese Journal of Rehabilitation Medicine. All right reserved.


Gu L.,Capital Institute of Physical Education | Yao L.,Capital Institute of Physical Education | You G.,Capital Institute of Physical Education
Chinese Journal of Rehabilitation Medicine | Year: 2011

Objective: To monitor the changes of cerebral blood oxygen reactions during movement and motor imagery with near infrared spectroscopy, to explore the theoretical basis of movement and motor imagery used in rehabilitation of patients with cerebral-vascular accident. Method: Sixty-four healthy college students were randomly divided into two groups: movement group and motor imagery group. Near infrared spectral technology was used to monitor the cerebral cortex cerebral blood oxygen metabolism during quiet and movement or motor imagery in both groups and the monitor results were compared and statistically analysed. Result: During movement oxy-Hb and total-Hb increased significantly, while deoxy-Hb decreased obviously. © During motor imagery oxy-Hb and total-Hb increased, and deoxy-Hb decreased also. Compared to during quiet the monitor results during movement and motor imagery were statistically significant different. Conclusion: Motor imagery and exercises can efficiently cause increasing of blood oxygen saturation of cerebral cortex and improve the corresponding regional cerebral blood oxygen supply.


Hao L.,Capital Institute of Physical Education | Wang Y.,Capital Institute of Physical Education | Duan Y.,Capital Institute of Physical Education | Bu S.,Capital Institute of Physical Education
European Journal of Applied Physiology | Year: 2010

To explore the mechanism(s) of exercise training on ovariectomized (OVX)-induced liver lipid disorder, we observed effects of treadmill training on liver fat accumulation and ERalpha expression in intact and ovariectomized rats. Sixty female rats were randomly assigned to six groups: Sham sedentary (S-S), Sham exercised (S-EX), ovariectomized sedentary (O-S), ovariectomized exercised (O-EX), ovariectomized injected subcutaneously with 17beta-estradiol (E2) (O-E2), and ovariectomized treated with E2 and exercise (O-E2-EX). Twelve weeks after intervention, OVX resulted in significantly higher body weight gain, intra-abdominal fat mass, serum levels of total cholesterol (TC), and liver triacylglycerol (TAG) concentrations and ERalpha expression than S-S group, while the relative uterus and liver mass, serum levels of E2, TAG, and the ratio of high density lipoprotein (HDL) to TC were markedly lower in O-S group. All of these changes were decreased in O-S rats after treatment with E2 alone with the exception of serum TC and HDL-C levels and liver ERalpha expression. Exercise alone significantly reversed the effect of OVX on serum E2, the ratio of HDL-C to TC and the liver and intra-abdominal fat accumulation in OVX rats. The addition of E2 to exercise induced the same uterus and lipid profile as E2 alone. Moreover, an additive effect of exercise and E2 was observed on liver ERalpha expression in Sham or OVX rats. In conclusion, treadmill training alone could prevent liver fat accumulation in OVX rats and the regulation of exercise on liver ERalpha expression in both OVX and Sham rats needs the presence of physical estrogen levels. © Springer-Verlag 2010.


Chen Y.,Capital Institute of Physical Education | Wang S.,Capital Institute of Physical Education | Bu S.,Capital Institute of Physical Education | Wang Y.,Capital Institute of Physical Education | And 2 more authors.
European Journal of Applied Physiology | Year: 2011

Exercise training has been reported to prevent bone loss in ovariectomized (OVX) rats and postmenopausal women. We hypothesized that treadmill training inhibited adipogenesis and enhanced osteogenesis through the regulation of adipocyte differentiation factor peroxisome proliferators-activated receptor gamma (PPARγ) and the osteogenic factor runt-related transcription factor 2 (Runx2) in a model of OVX-induced osteoporosis. To test this hypothesis, 3-month-old female Sprague-Dawley rats were divided randomly into the following groups: Sham, OVX, OVX exercised (EX), and OVX estrogen replacement (E 2). At the end of the experiment, the bone mineral density (BMD) was detected using DEXA and the morphology change of bone tissues and uterus was observed by HE staining. The protein expression for PPARγ and Runx2 were measured by immunohistochemistry and western blot and the bone triacylglycerol (TG) was extracted by methanol/ chloroform. OVX dramatically increased the number of fat vacuoles, protein levels for PPARγ and Runx2 as well as the TG level in tibiae and lumbar vertebrate. In contrast, the serum level of E 2, the lumbar vertebrate BMD as well as the proximal and distal femur BMD was significantly decreased in the OVX group. All changes induced by OVX were significantly reversed by exercise treatment except for the protein expression level of Runx2. Moreover, exercise treatment produced no estrogenic effects on uterus as evidenced by the uterus wet weight and histology. Treadmill training could prevent bone loss induced by OVX through the inhibition of adipocyte differentiation factor PPARγ rather than promoting osteogenic factor Runx2. © Springer-Verlag 2010.


Wang Y.,Capital Institute of Physical Education | Wisloff U.,Norwegian University of Science and Technology | Kemi O.J.,University of Glasgow
Physiological Research | Year: 2010

Exercise training-induced cardiac hypertrophy occurs following a program of aerobic endurance exercise training and it is considered as a physiologically beneficial adaptation. To investigate the underlying biology of physiological hypertrophy, we rely on robust experimental models of exercise training in laboratory animals that mimic the training response in humans. A number of experimental strategies have been established, such as treadmill and voluntary wheel running and swim training models that all associate with cardiac growth. These approaches have been applied to numerous animal models with various backgrounds. However, important differences exist between these experimental approaches, which may affect the interpretation of the results. Here, we review the various approaches that have been used to experimentally study exercise training-induced cardiac hypertrophy; including the advantages and disadvantages of the various models. © 2010 Institute of Physiology v.v.i., Academy of Sciences of the Czech Republic.


Zhu H.,Capital Institute of Physical Education | Wei Y.,Capital Institute of Physical Education | He L.,Capital Institute of Physical Education
Proceedings - 2012 IEEE Symposium on Robotics and Applications, ISRA 2012 | Year: 2012

Stem and Leaf Graph is a new kind of graphic method which is quite popular in showing the distribution of the data using data itself in statistic nowadays. Although there is Stem and Leaf Graph in SPSS that can handle single samples, Back-to-Back Stem and Leaf Graph remains a blank, as well as in Excel. This paper provides a thought of generating Back-to-Back Stem and Leaf Graph automatically with the existing functions in Excel, which has used in shooting statistical analysis and proof the correctness in any condition of rational. It can not only provide a new choice for users of Stem and Leaf Graph, but also fill in the blank for Sports Statistics using Excel as a calculation tool. © 2012 IEEE.

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