Theodorou M.,Cancer Research Cancer Imaging Center |
Fromageau J.,Cancer Research Cancer Imaging Center |
Desouza N.,Cancer Research Cancer Imaging Center |
Desouza N.,Royal Marsden NHS Foundation Trust |
Bamber J.C.,Cancer Research Cancer Imaging Center
2015 IEEE International Ultrasonics Symposium, IUS 2015 | Year: 2015
In poroelastography a region of soft tissue is compressed, and the fluid within its compartments escapes its boundaries causing a time- and spatially-varying deformation of its matrix that may be imaged as the ultrasound echo strain over time. Such strain movies allow the quantitative imaging of the product of the tissue's aggregate modulus and permeability, HAk, and its Poisson's ratio, v. Shear wave elastography provides movies of Young's modulus, E. This study demonstrates in phantoms the potential of combining simultaneous dynamic shear wave and strain elastography to separate the components of HAk, and therefore recover k, independently of v and E. We refer to this new method as permelastography. © 2015 IEEE.