Cancer Epidemiology and Cytopathology in Tunisian Center

Medicine, Tunisia

Cancer Epidemiology and Cytopathology in Tunisian Center

Medicine, Tunisia

Time filter

Source Type

Missaoui N.,Cancer Epidemiology and Cytopathology in Tunisian Center | Missaoui N.,Farhet Hached University Hospital | Abdelkader A.B.,Farhet Hached University Hospital | Beizig N.,Farhet Hached University Hospital | And 4 more authors.
Asian Pacific Journal of Cancer Prevention | Year: 2010

Introduction: Colorectal cancer is the third most commonly diagnosed cancer worldwide. Design: In order to review the clinical and pathological features of colorectal cancer in Tunisia, a retrospective study was carried out on 1,443 cancer cases diagnosed in the Pathology Department, Farhet Hached University Hospital of Sousse, for a 15-year period (1993-2007). Results: The median age was 61 years. Adenocarcinoma was the most frequent (90.9%) with moderately differentiated tumors accounting for 76.7% of cases. Only eighty patients were identified as being in early stages (0 and A) and 85.8% in advanced stages (B-D). Over time, we observed a significant decrease of stage B (p=0.02) and a significant increase of stage D (p=0.002). The tumor size was larger than 5 cm in 67.5% of cases. Conclusion: The large proportion of patients presented at advanced stages, compared to only 5.5% of patients at early stages, emphasizes the need to plan and develop a screening program for the early detection of this cancer and its precursor lesions in Tunisia.


Missaoui N.,Cancer Epidemiology and Cytopathology in Tunisian Center | Missaoui N.,University of Sousse | Landolsi H.,University of Sousse | Anjorin A.,University of Sousse | And 4 more authors.
Asian Pacific Journal of Cancer Prevention | Year: 2010

Introduction: Rhabdomyosarcoma is the most common soft tissue sarcoma in the first two decades of life. Since there is a paucity of reports on the pattern of its occurrence in Tunisia, we here analysed the epidemiological pattern, clinical features, and pathology. Design: We retrospectively studied 30 consecutive cases of histologically proven rhabdomyosarcoma in children aged 0-15 years extracted from the database of the Cancer Registry of the Center of Tunisia for the period 1993-2007. Results: Rhabdomyosarcomas represented 53.6% of soft tissue sarcomas and 3.8% of all children cancer cases registered during this period. The male/female ratio was 2.7 with a mean age at diagnosis of 5.9 years. The embryonal subtype was the most frequent (60%) and the two most common sites of disease were the head and neck (50%) and genito-urinary tract(23.3%). Chemotherapy was used in 90% of patients; 43.3% of patients had radical surgery and 26.7% of patients received radiation therapy. Conclusion: The epidemiology, pathology and clinical features of rhabdomyosarcoma in Tunisian children are close to those reported from other countries.


PubMed | Cancer Epidemiology and Cytopathology in Tunisian Center
Type: Journal Article | Journal: Asian Pacific journal of cancer prevention : APJCP | Year: 2011

Significant variation in colorectal cancer incidence rates and trends has been observed across countries. Data from Tunisia are sparse. In this paper, we analyzed trends in incidence rates of the colorectal cancer over a 15-year period, 1993-2007, in Central Tunisia.Five-year age-specific rates, crude incidence rates, world age-standardized rates, and annual percent change were calculated using annual data on population size and its estimated age structure.A total of 1,443 incident cases of colorectal cancer were registered, with a male to-female sex ratio of 1.1:1. The world age-standardized rate was 10.0 per 100,000 among females and 11.7 among males. Over time, there were significant increasing trends by +2.6% (95% CI: 0.1%, 5.1%) and +5.3% (95% CI: 2.7%, 7.9%) for females and males, respectively.The absence of a screening program for colorectal cancer could explain the increasing trends observed among males and females in Central Tunisia. Our findings point the need to plan and develop effective programs aimed at the control and prevention of the spread of colorectal cancer in Tunisia.


PubMed | Cancer Epidemiology and Cytopathology in Tunisian Center
Type: Journal Article | Journal: Asian Pacific journal of cancer prevention : APJCP | Year: 2011

Colorectal cancer is the third most commonly diagnosed cancer worldwide.In order to review the clinical and pathological features of colorectal cancer in Tunisia, a retrospective study was carried out on 1,443 cancer cases diagnosed in the Pathology Department, Farhet Hached University Hospital of Sousse, for a 15-year period (1993-2007).The median age was 61 years. Adenocarcinoma was the most frequent (90.9%) with moderately differentiated tumors accounting for 76.7% of cases. Only eighty patients were identified as being in early stages (0 and A) and 85.8% in advanced stages (B-D). Over time, we observed a significant decrease of stage B (p=0.02) and a significant increase of stage D (p=0.002). The tumor size was larger than 5 cm in 67.5% of cases.The large proportion of patients presented at advanced stages, compared to only 5.5% of patients at early stages, emphasizes the need to plan and develop a screening program for the early detection of this cancer and its precursor lesions in Tunisia.


PubMed | Cancer Epidemiology and Cytopathology in Tunisian Center
Type: Journal Article | Journal: Asian Pacific journal of cancer prevention : APJCP | Year: 2011

Rhabdomyosarcoma is the most common soft tissue sarcoma in the first two decades of life. Since there is a paucity of reports on the pattern of its occurrence in Tunisia, we here analysed the epidemiological pattern, clinical features, and pathology.We retrospectively studied 30 consecutive cases of histologically proven rhabdomyosarcoma in children aged 0-15 years extracted from the database of the Cancer Registry of the Center of Tunisia for the period 1993-2007.Rhabdomyosarcomas represented 53.6% of soft tissue sarcomas and 3.8% of all children cancer cases registered during this period. The male/female ratio was 2.7 with a mean age at diagnosis of 5.9 years. The embryonal subtype was the most frequent (60%) and the two most common sites of disease were the head and neck (50%) and genito-urinary tract(23.3%). Chemotherapy was used in 90% of patients; 43.3% of patients had radical surgery and 26.7% of patients received radiation therapy.The epidemiology, pathology and clinical features of rhabdomyosarcoma in Tunisian children are close to those reported from other countries.

Loading Cancer Epidemiology and Cytopathology in Tunisian Center collaborators
Loading Cancer Epidemiology and Cytopathology in Tunisian Center collaborators