Lacombe, Canada

Canadian University College
Lacombe, Canada

Canadian University College is an independent publicly funded university located in Lacombe. It is sponsored by the Seventh-day Adventist Church in Canada and is affiliated with the Association of Theological Schools. The school's official mission statement is to educate learners to think with discernment, to believe with insight and commitment and to act with confidence, compassion, and competence. The college places emphasis on service in local and global communities. Wikipedia.

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PubMed | University of Ontario Institute of Technology, Canadian University College, Graduate Education and Research Programs, Clinical Research Coordinator and University of Alberta
Type: Journal Article | Journal: The Journal of the Canadian Chiropractic Association | Year: 2016

To determine the effectiveness of structured patient education for the management of musculoskeletal disorders and injuries of the extremities.We searched MEDLINE, EMBASE, CINAHL, PsycINFO, and the Cochrane Central Register of Controlled Trials from January 1, 1990 to March 14, 2015. Paired reviewers independently screened titles and abstracts for eligibility. The internal validity of studies was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) criteria. Results from studies with a low risk of bias were synthesized using the best-evidence synthesis methodology.We identified two randomized trials with a low risk of bias. Our review suggests that: 1) multimodal care and corticosteroid injections lead to faster pain relief and improvement than reassurance and advice in the short-term and similar outcomes in the long-term for patients with persistent lateral epicondylitis; and 2) providing health education material alone may be less effective than multimodal care for the management of persistent patellofemoral pain syndrome.Our systematic search of the literature demonstrates that little is known about the effectiveness of structured patient education for the management of musculoskeletal disorders and injuries of the extremities. Two studies suggest that when used alone, structured patient education may be less effective than other interventions used to manage persistent lateral epicondylitis and persistent patellofemoral syndrome.

PubMed | Center for Operational Research in Africa, McMaster University, Union University Tennessee, Mulago National Referral Hospital and 2 more.
Type: Journal Article | Journal: In silico pharmacology | Year: 2016

Plasma albumin, a biomarker for hepatic function, is reported to correspondingly decrease in concentration as disease severity increases in chronic infections including HIV and TB. Our objective was to develop a semi-mechanistic disease progression model to quantify plasma albumin concentration changes during TB and HIV therapy and identify the associated covariate factors.Plasma albumin concentration data was collected at specified times for 3 months from 262 HIV participants receiving efavirenz based anti retroviral therapy. Of these, 158 were TB co-infected and on Rifampicin based anti -tuberculosis co-treatment. An indirect response model with zero order albumin production and first order elimination was developed in NONMEM version 7.2 to describe our data. Genotype (CYP2B6*6 and 11, CYP3A5, ABCB1c.3435C>T and ABCB1rs), TB disease status, baseline age, body weight, plasma creatinine, alanine transaminase enzyme and CD4(+) count were the potential model covariates tested.The proposed model successfully described plasma albumin concentration changes in the study population. There was a 10.9% and 48.6% increase in albumin production rates in HIV only and TB co-infected participants respectively. Participants co-infected with TB showed a 44.2% lower baseline albumin secretion rate than those without TB while ABCB1c.3435C>T mutation was associated with a 16% higher steady state albumin secretion rate following treatment.A semi-mechanistic model describes plasma albumin concentration changes in HIV patients on ART. Further work is required to establish the utility of the model in monitoring disease progression and predicting prognosis in HIV and TB co-infected patients in absence of or during treatment.

Moslem B.,CNRS Biomechanical Engineering Laboratory | Moslem B.,Lebanese University | Diab M.O.,Canadian University College | Khalil M.,Lebanese University | Marque C.,CNRS Biomechanical Engineering Laboratory
2011 IEEE Workshop on Signal Processing Systems, SiPS 2011, Proceedings | Year: 2011

Multichannel analysis is an innovative technique used for the analysis of bioelectrical signals. In this paper, we analyzed uterine Electromyogram (EMG) signals recorded by means of a 4x4 electrode matrix positioned on the woman's abdomen by using a multichannel approach. Relevant features were extracted from each channel and fed to a competitive neural network (CNN). First, we evaluated the classification performance of each channel. Then, we compared these performances to see which channel ranks better than the others. Finally, a decision fusion method based on the weighted sum of the individual decision of each channel was tested. The results showed that data can be grouped into 2 different groups. Furthermore, they showed that the classification performance varies according to the position of the electrode. Therefore, when a decision fusion rule was applied, the network yielded better classification accuracy than any individual channel could provide. These encouraging results prove that multichannel analysis can improve the classification of uterine EMG signals. © 2011 IEEE.

Moslem B.,CNRS Biomechanical Engineering Laboratory | Moslem B.,Reykjavik University | Karlsson B.,Canadian University College | Diab M.O.,Lebanese University | And 2 more authors.
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS | Year: 2011

Frequency-related parameters derived from the uterine electromyogram (EMG) signals are widely used in many pregnancy monitoring and preterm delivery prediction studies. Although they are classical parameters, they are well suited for quantifying uterine EMG signals and have many advantages over amplitude-related parameters. The present work aims to compare various frequency-related parameters according to their classification performances (pregnancy vs. labor) using the receiver operating characteristic (ROC) curve analysis. The comparison between the parameters indicates that median frequency is the best frequency-related parameter that can be used for distinguishing between pregnancy and labor contractions. We conclude that median frequency can be the representative frequency-related parameter for classification problems of uterine EMG. © 2011 IEEE.

PubMed | Natural History Museum in London, Canadian University College, University of Basel, Academy of Sciences of the Czech Republic and 2 more.
Type: Journal Article | Journal: Proceedings of the National Academy of Sciences of the United States of America | Year: 2015

The decline of amphibian populations, particularly frogs, is often cited as an example in support of the claim that Earth is undergoing its sixth mass extinction event. Amphibians seem to be particularly sensitive to emerging diseases (e.g., fungal and viral pathogens), yet the diversity and geographic distribution of infectious agents are only starting to be investigated. Recent work has linked a previously undescribed protist with mass-mortality events in the United States, in which infected frog tadpoles have an abnormally enlarged yellowish liver filled with protist cells of a presumed parasite. Phylogenetic analyses revealed that this infectious agent was affiliated with the Perkinsea: a parasitic group within the alveolates exemplified by Perkinsus sp., a marine protist responsible for mass-mortality events in commercial shellfish populations. Using small subunit (SSU) ribosomal DNA (rDNA) sequencing, we developed a targeted PCR protocol for preferentially sampling a clade of the Perkinsea. We tested this protocol on freshwater environmental DNA, revealing a wide diversity of Perkinsea lineages in these environments. Then, we used the same protocol to test for Perkinsea-like lineages in livers of 182 tadpoles from multiple families of frogs. We identified a distinct Perkinsea clade, encompassing a low level of SSU rDNA variation different from the lineage previously associated with tadpole mass-mortality events. Members of this clade were present in 38 tadpoles sampled from 14 distinct genera/phylogroups, from five countries across three continents. These data provide, to our knowledge, the first evidence that Perkinsea-like protists infect tadpoles across a wide taxonomic range of frogs in tropical and temperate environments, including oceanic islands.

Halablab M.A.,Canadian University College | Sheet I.H.,Beirut Arab University | Holail H.M.,Beirut Arab University
American Journal of Food Technology | Year: 2011

The purpose of this study was to assess the microbiological quality of fresh vegetables collected from several regions in Bekaa Valley areas. A total of 63 vegetable samples irrigated from Litani River in Bekaa Valley in Lebanon namely lettuce, parsley and Malua samples and other control vegetables samples irrigated from ground water wells were examined to assess microbial contamination level. The microbiological quality of fresh vegetables ranged from 4.3 to 10.4 log 10 CFU g -1 (aerobic bacteria); 2.0 to 0.71 log 10 CFU g -1 (cohforns); 1.0 to 8.77 log 10 CFU g -1 (E. coli) and 1.47 to 8.77 log 10 CFU g -1 (S. aureus). Lettuce samples had significantly higher microbial loads including coliforms, E. coli and S. aureus than parsley samples collected from different locations in Bekaa Valley. Neither E. coli nor S. aureus had been detected on Malva samples. In addition, Barelias had higher microbial loads, coliform, E. coli and S. aureus than any other location investigated in Bekaa Valley. Moreover, E. coli was significantly higher in lettuce samples (42.30%) than in parsley samples (13.8%) and S. aureus was significantly more often detected in lettuce samples (51.5%) than in parsley samples (38%). This study demonstrated that lettuce and parsley which are usually consumed raw may contain pathogenic microorganisms and represent a risk for human health. © 2011 Academic Journals Inc.

Halablab M.A.,Canadian University College | Hijazi S.M.,Beirut Arab University | Fawzi M.A.,Beirut Arab University | Araj G.F.,American University of Beirut
Epidemiology and Infection | Year: 2010

The increasing prevalence of Staphylococcus aureus and methicillin- resistant S. aureus (MRSA) strains together with their disease impact on hospital patients and individuals in the community has posed a major challenge to healthcare workers. This study examined the prevalence of S. aureus nasal carriage, antimicrobial susceptibility patterns, and possible risk factors in the community. Of 500 studied subjects (aged from 6 to 65 years) in Lebanon, the overall S. aureus nasal carriage rate was 384%, the highest (571%) being in children aged 6-10 years. Only eight individuals (16%) were carriers of MRSA. Risk factors for S. aureus nasal colonization were male gender, young age, contact with healthcare workers, use of needle injections, and having asthma. A significant decrease in colonization rate was associated with nasal wash with water, use of nasal sprays, and the presence of acne. These findings may assist in better understanding of control measures to decrease nasal colonization with S. aureus in Lebanon and elsewhere. © Cambridge University Press 2009.

Drug resistance is a key cause of failed treatment of HIV infection. The efficacy of nonnucleoside reverse transcriptase-inhibiting (NNRTI) drugs is impaired by the rapid emergence of drug-resistant mutations. The literature supports the idea that purposefully designed flexible NNRTIs at an active site may help overcome drug resistance. It is proposed here that the usual "lock and key" model, with respect to NNRTI drug design, be expanded to consider creating "master keys" that would automatically adjust conformations to fit all of the "locks" mutations may make. The present work introduces the novel perspective of designing and creating supramolecular assemblies as potential NNRTIs (instead of the relatively more rigid single-molecule inhibitors). Specifically, flexible self-assembling quinhydrone supramolecular dimers formed from quinonoid monomers (designed to be highly flexible NNRTIs themselves) will be offered as a working example of this new perspective in NNRTI drug design. Quinonoid compounds have demonstrated binding interactions at various sites of the HIV-1 RT enzyme, including the elusive ribonuclease H area. Quinhydrone self-organized dimers have at some point in their molecular architecture a noncovalently interacting donor-acceptor ring pair complex. This complex is at the heart of the increased torsional, rotational, and translational motion this species will experience at a particular active site. Flexible supramolecular assemblies, together with their flexible monomer components, may offer a critical advantage in retaining potency against a wide range of drug-resistant HIV-1 RTs. This new supramolecular perspective may also have broader implications in the general field of antimicrobial drug design. © Copyright 2013, Mary Ann Liebert, Inc. 2013.

Zbib N.,Canadian University College | Al-Hamra A.,Canadian University College
2012 8th International Symposium on Mechatronics and its Applications, ISMA 2012 | Year: 2012

In this paper we introduce a new application of potential field concept that is used for resource management in distributed environments. More precisely, we propose an efficient algorithm to assist the medial staff in a hospital to deal with a crisis caused by receiving a large number of patients simultaneously. Our algorithm runs by all member of the medical team in parallel and guides every team member in his/her choice of which patient to rescue at every moment. Our extensive simulation results show that our algorithm achieves very efficient results. In some scenarios, the percentage of saved patients exceeds 82%. In addition, our results show a fair distribution of the load over the different nurses. © 2012 IEEE.

Nuwayhid R.Y.,Canadian University College
Acta Horticulturae | Year: 2010

Chestnut planting in Lebanon apparently found a small place some fifteen years ago. A score of individuals created orchards that contained anything from 20 to 500 trees. The trees were not selected by any standard and were obtained from whatever source available at the time and planted haphazardly resulting in some failures. On the other hand some chestnuts orchards are doing quite well and attest to the possibility of chestnut success in Lebanon. As such tree vigor and soil analysis is reported in the chestnut stands and some conclusions are drawn. Looking back in time and trying to find out if chestnut or related arboreal species may have been historically or are currently represented in Lebanon provides guidance on possible success in today's Lebanon. Together with the identification of existent aging specimen trees, this study follows up on previous work and reports on the current condition of chestnut planting in Lebanon.

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