Calon Cardio Technology Ltd

Swansea, United Kingdom

Calon Cardio Technology Ltd

Swansea, United Kingdom

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Patent
Calon Cardio Technology Ltd. | Date: 2015-06-09

A cardiac pump includes a plain bearing assembly having a first plain bearing portion that is coupled to a cardiac pump rotor and a second plain bearing portion that is coupled to a cardiac pump housing. The plain bearing assembly is configured to rotatably support the cardiac pump rotor within the cardiac pump housing in at least an axial direction of the cardiac pump rotor. A magnetic bearing assembly includes a first magnetic bearing portion that is coupled to the cardiac pump rotor and a second magnetic bearing portion that is coupled to the cardiac pump housing. The magnetic bearing assembly is configured to rotatably support the cardiac pump rotor within the cardiac pump housing in a radial direction of the cardiac pump rotor and bias the cardiac pump rotor in the axial direction such that the magnetic bearing assembly provides a preload force to preload the plain bearing assembly.


Patent
Calon Cardio Technology Ltd. | Date: 2017-04-19

A cardiac pump (101, 201, 301) comprising: a plain bearing assembly (126, 226, 326) comprising a first plain bearing portion (126a, 226a, 326a) and a second plain bearing portion (126b, 226b, 326b), the first plain bearing portion (126a, 226a, 326a) being coupled to a cardiac pump rotor (108, 208, 308) and the second plain bearing portion (126b, 226b, 326b) being coupled to a cardiac pump housing (107, 207, 308), the plain bearing assembly (126, 226, 326) being configured to rotatably support the cardiac pump rotor (108, 208, 308) within the cardiac pump housing (107, 207, 307) in at least an axial direction of the cardiac pump rotor (108, 208, 308); and a magnetic bearing assembly (136, 236, 336) comprising a first magnetic bearing portion (136a, 236a, 336a) and a second magnetic bearing portion (136b, 236b, 336b), the first magnetic bearing portion (136a, 236a, 336a) being coupled to the cardiac pump rotor (108, 208, 308) and the second magnetic bearing portion (136b, 236b, 336b) being coupled to the cardiac pump housing (107, 207, 307), the magnetic bearing assembly (136, 236, 336) being configured to rotatably support the cardiac pump rotor (108, 208, 308) within the cardiac pump housing (107, 207, 307) in a radial direction of the cardiac pump rotor (108, 208, 308) and bias the cardiac pump rotor (108, 208, 308) in the axial direction such that the magnetic bearing assembly (136, 236, 336) provides a preload force to preload the plain bearing assembly (126, 226, 326).


Chan C.H.H.,University of Swansea | Chan C.H.H.,Calon Cardio Technology Ltd | Hilton A.,Calon Cardio Technology Ltd | Foster G.,Calon Cardio Technology Ltd | Hawkins K.,University of Swansea
Artificial Organs | Year: 2012

The Harboe spectrophotometric assay is regarded as one of the safest and most reproducible methods for measuring plasma free hemoglobin (pfHb). However, there is still some ambiguity in the application of the assay when assessing the hemolytic performance of ventricular assist devices (VADs). The purpose of this study was to reexamine and compare values of pfHb obtained using different concentrations of plasma diluent (Na2CO3) as cited by various studies such that a standard practice may be recommended for the application of the Harboe assay in the hemolytic evaluation of VADs, allowing reliable comparisons to be made between laboratories. As a means to examine the Harboe assay, a BioMedicus BPX-80 was tested using both whole blood and a washed suspension of red blood cells (RBCs). Results show that for whole blood, the pfHb may be underestimated by 13-23%, dependent upon the concentration of Na2CO3 diluent solution. This trend was not observed for the washed suspension of RBCs. Furthermore, it is shown that the concentration of diluent influences the stability of a sample. The results of this study show that the problems associated with the incongruity of pfHb readings are a direct result of the precipitation of proteins from the plasma under alkaline conditions; as the molarity of the diluent controls pH, it becomes essential to use the appropriate concentration of Na2CO3 diluent in order to avoid turbidity of the solution and the consequent misrepresentation of pfHb values. Such standardization is pertinent when measuring the very low levels of pfHb observed during the in vivo testing of modern ventricular assist devices. © 2012, the Authors. Artificial Organs © 2012, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.


Trademark
Calon Cardio Technology Ltd | Date: 2012-06-05

Surgical and medical apparatus and instruments for use in cardiac surgery and parts and fittings sold therewith; cardiac implant devices and heart pumps made of artificial materials and parts and fittings sold therewith; cannulae; catheters.


Trademark
Calon Cardio Technology Ltd | Date: 2012-06-05

Surgical and medical apparatus and instruments for use in cardiac surgery and parts and fittings sold therewith; cardiac implant devices and heart pumps made of artificial materials and parts and fittings sold therewith; cannulae; catheters.


Grant
Agency: GTR | Branch: Innovate UK | Program: | Phase: Collaborative Research & Development | Award Amount: 1.67M | Year: 2013

Advanced heart failure is a large and growing healthcare challenge not adequately met by traditional medical management, cardiac resynchronisation or transplantation. Ventricular assist devices (VADs) can address this need and have shown very promising clinical results. However, existing VADs are expensive, have high utilisation costs due to significant complications and require extensive invasive surgery for implantation. Calon’s MiniVAD addresses these problems with a smaller pump, reduced blood damage and significantly improved health economics. This project proposes the development of novel blood damage assays and the subsequent detailed in-vitro and in-vivo evaluation of the MiniVAD to provide the performance and safety data necessary to support a regulatory application to begin human clinical studies


Patent
Calon Cardio Technology Ltd | Date: 2010-04-19

The pump is of an axial flow rotary pump, suitable for implantation into the human heart or vascular system, and comprises an elongate tubular casing (1,2) defining an inlet (4) for blood, an outlet (5) for blood longitudinally spaced from the inlet, and a primary substantially axial blood flow path (6) along the interior of the casing from the inlet to the outlet, the casing including an electric motor stator (7). There is an elongate rotatable element (3) arranged to fit within the casing with spacing between an outer surface of the rotatable element and an inner surface of the casing. The tubular rotatable element comprises an electric motor rotor portion (10) arranged to be driven by the electric motor stator and a rotary impeller (11) for impelling blood along the blood flow path. The casing is formed as an upstream tubular member (2) having an open front end, and a downstream tubular member (1) having open front and rear ends, the upstream tubular member including the stator, and the downstream tubular member, which encircles the impeller, having a rear end fitted to the upstream tubular member in fluid tight manner.


Patent
Calon Cardio Technology Ltd | Date: 2013-10-17

The pump, which is for implantation into a human heart, has a flow path through a housing (1), a rotatable pump member (21) within the housing for causing fluid to flow along the flow path, the pump member being rotatably coupled to the housing about an upstream bearing (32) and a downstream bearing (33). The downstream bearing comprises a bearing member (34) on the pump member and a complementary bearing formation (35) on the housing, The pump has a mechanical adjuster (42) for fine adjustment of the position of the bearing formation (35) along an axis (A) of the pump member; the mecahnical adjuster being preferably one or more screws (42) for adjustable movement of a boss (40) along the axis (A), the adjustable movement being permitted by flexure of a plate member (41) integral with the boss.


Patent
Calon Cardio Technology Ltd | Date: 2012-07-18

The cardiac pump, which is suitable for implantation into a ventricle of a human heart, has a primary blood flow path through a housing, a rotatable pump member disposed within the housing for causing blood to flow along the primary flow path, the pump member being rotatably coupled to the housing about an upstream bearing and a downstream bearing. The pump member includes an impeller shroud defining a secondary flow path in fluid communication with the primary flow path. The downstream bearing comprises a rotational bearing member and a stationary bearing seat for the bearing member, there being a circumferential transition between the bearing seat and the bearing member, the circumferential transition being disposed in the secondary flow path and arranged to be washed by blood passing along the secondary flow path.


Patent
Calon Cardio Technology Ltd. | Date: 2014-05-21

A plain bearing assembly for a cardiac pump, the plain bearing assembly comprising; a rotational portion which, in use, rotates with a cardiac pump rotor, the rotational portion configured to engage a stationary portion of a cardiac pump housing, the stationary portion comprising one or more first bearing surfaces and the rotational portion comprising one or more second bearing surfaces, the one or more second bearing surfaces configured so as to be in contact with the one or more first bearing surfaces, therein defining a bearing interface between the one or more first bearing surfaces and the one or more second bearing surfaces during rotation of the rotational portion, wherein the rotational portion comprises one or more first flow channels configured to interrupt the bearing interface and permit blood to flow between an outside of the plain bearing assembly and a center of the plain bearing assembly.

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