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Yarmoshenko I.V.,Russian Academy of Sciences | Vasilyev A.V.,Russian Academy of Sciences | Onishchenko A.D.,Russian Academy of Sciences | Kiselev S.M.,Burnasyan Federal Medical Biophysical Center | Zhukovsky M.V.,Russian Academy of Sciences
Radiation Protection Dosimetry | Year: 2014

Modern energy-efficient architectural solutions and building construction technologies such as monolithic concrete structures in combination with effective insulation reduce air permeability of building envelope. As a result, air exchange rate is significantly reduced and conditions for increased radon accumulation in indoor air are created. Based on radon survey in Ekaterinburg, Russia, remarkable increase in indoor radon concentration level in energy-efficient multi-storey buildings was found in comparison with similar buildings constructed before the-energy-saving era. To investigate the problem of indoor radon in energyefficient multi-storey buildings, the measurements of radon concentration have been performed in seven modern buildings using radon monitoring method. Values of air exchange rate and other parameters of indoor climate in energy-efficient buildings have been estimated. © The Author 2014. Published by Oxford University Press. All rights reserved.

Zhukovsky M.,Russian Academy of Sciences | Yarmoshenko I.,Russian Academy of Sciences | Kiselev S.,Burnasyan Federal Medical Biophysical Center
Journal of Environmental Radioactivity | Year: 2012

The typical method of radon mapping usually used in most countries is the presenting of average radon concentrations in dwellings for districts or regions. Sometimes the maps of radon concentrations in the soil or maps of percentage above the reference level also demonstrated. Such approach not always can be used for identification of the regions with high probability of radon exposure above the reference levels where the population density is low. The combination of archive geological data and the results of representative radon survey allow estimating the typical parameters of radon concentration distribution for selected categories of buildings (multi-storey or rural type houses) situated in geological zones with the different radon potential. In this case it is possible to give grounds for the necessary level of radon protection measures in the new buildings constructed in this region. The use of such approach in Ural region of Russia is demonstrated. © 2012 Elsevier Ltd.

Khrutchinsky A.,Institute for Nuclear Problems | Drozdovitch V.,U.S. National Cancer Institute | Kutsen S.,Institute for Nuclear Problems | Minenko V.,Belarusian Medical Academy of Post Graduate Education | And 4 more authors.
Applied Radiation and Isotopes | Year: 2012

This paper presents results of Monte Carlo modeling of the SRP-68-01 survey meter used to measure exposure rates near the thyroid glands of persons exposed to radioactivity following the Chernobyl accident. This device was not designed to measure radioactivity in humans. To estimate the uncertainty associated with the measurement results, a mathematical model of the SRP-68-01 survey meter was developed and verified. A Monte Carlo method of numerical simulation of radiation transport has been used to calculate the calibration factor for the device and evaluate its uncertainty. The SRP-68-01 survey meter scale coefficient, an important characteristic of the device, was also estimated in this study. The calibration factors of the survey meter were calculated for 131I, 132I, 133I, and 135I content in the thyroid gland for six age groups of population: newborns; children aged 1yr, 5yr, 10yr, 15yr; and adults. A realistic scenario of direct thyroid measurements with an "extended" neck was used to calculate the calibration factors for newborns and one-year-olds. Uncertainties in the device calibration factors due to variability of the device scale coefficient, variability in thyroid mass and statistical uncertainty of Monte Carlo method were evaluated. Relative uncertainties in the calibration factor estimates were found to be from 0.06 for children aged 1yr to 0.1 for 10-yr and 15-yr children. The positioning errors of the detector during measurements deviate mainly in one direction from the estimated calibration factors. Deviations of the device position from the proper geometry of measurements were found to lead to overestimation of the calibration factor by up to 24 percent for adults and up to 60 percent for 1-yr children. The results of this study improve the estimates of 131I thyroidal content and, consequently, thyroid dose estimates that are derived from direct thyroid measurements performed in Belarus shortly after the Chernobyl accident. © 2012.

Little M.P.,U.S. National Cancer Institute | Kwon D.,University of Miami | Zablotska L.B.,University of California at San Francisco | Brenner A.V.,U.S. National Cancer Institute | And 7 more authors.
PLoS ONE | Year: 2015

Background The excess incidence of thyroid cancer in Ukraine and Belarus observed a few years after the Chernobyl accident is considered to be largely the result of 131I released from the reactor. Although the Belarus thyroid cancer prevalence data has been previously analyzed, no account was taken of dose measurement error. Methods We examined dose-response patterns in a thyroid screening prevalence cohort of 11,732 persons aged under 18 at the time of the accident, diagnosed during 1996-2004, who had direct thyroid 131I activity measurement, and were resident in the most radio-actively contaminated regions of Belarus. Three methods of dose-error correction (regression calibration, Monte Carlo maximum likelihood, Bayesian Markov Chain Monte Carlo) were applied. Results There was a statistically significant (p<0.001) increasing dose-response for prevalent thyroid cancer, irrespective of regression-adjustment method used. Without adjustment for dose errors the excess odds ratio was 1.51 Gy- (95% CI 0.53, 3.86), which was reduced by 13% when regression-calibration adjustment was used, 1.31 Gy- (95% CI 0.47, 3.31). A Monte Carlo maximum likelihood method yielded an excess odds ratio of 1.48 Gy- (95% CI 0.53, 3.87), about 2% lower than the unadjusted analysis. The Bayesian method yielded a maximum posterior excess odds ratio of 1.16 Gy- (95% BCI 0.20, 4.32), 23% lower than the unadjusted analysis. There were borderline significant (p = 0.053-0.078) indications of downward curvature in the dose response, depending on the adjustment methods used. There were also borderline significant (p = 0.102) modifying effects of gender on the radiation dose trend, but no significant modifying effects of age at time of accident, or age at screening as modifiers of dose response (p>0.2). Conclusions In summary, the relatively small contribution of unshared classical dose error in the current study results in comparatively modest effects on the regression parameters.

Drozdovitch V.,U.S. National Cancer Institute | Minenko V.,Institute for Nuclear Problems | Golovanov I.,Burnasyan Federal Medical Biophysical Center | Khrutchinsky A.,Institute for Nuclear Problems | And 8 more authors.
Radiation Research | Year: 2015

Deterministic thyroid radiation doses due to iodine-131 (131I) intake were reconstructed in a previous article for 11,732 participants of the Belarusian-American cohort study of thyroid cancer and other thyroid diseases in individuals exposed during childhood or adolescence to fallout from the Chernobyl accident. The current article describes an assessment of uncertainties in reconstructed thyroid doses that accounts for the shared and unshared errors. Using a Monte Carlo simulation procedure, 1,000 sets of cohort thyroid doses due to 131I intake were calculated. The arithmetic mean of the stochastic thyroid doses for the entire cohort was 0.68 Gy. For two-thirds of the cohort the arithmetic mean of individual stochastic thyroid doses was less than 0.5 Gy. The geometric standard deviation of stochastic doses varied among cohort members from 1.33 to 5.12 with an arithmetic mean of 1.76 and a geometric mean of 1.73. The uncertainties in thyroid dose were driven by the unshared errors associated with the estimates of values of thyroid mass and of the 131I activity in the thyroid of the subject; the contribution of shared errors to the overall uncertainty was small. These multiple sets of cohort thyroid doses will be used to evaluate the radiation risks of thyroid cancer and noncancer thyroid diseases, taking into account the structure of the errors in the dose estimates. © 2015 by Radiation Research Society.

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