Bundesforschungsinstitut For Tiergesundheit

Braunschweig, Germany

Bundesforschungsinstitut For Tiergesundheit

Braunschweig, Germany

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Jacob J.,Julius Kuhn Institute | Ulrich R.G.,Bundesforschungsinstitut For Tiergesundheit | Freise J.,Task Force Veterinarwesen | Schmolz E.,FG IV 1.4 Gesundheitsschadlinge und ihre Bekampfung
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz | Year: 2014

Rodents can harbor and transmit pathogens that can cause severe disease in humans, companion animals and livestock. Such zoonotic pathogens comprise more than two thirds of the currently known human pathogens. The epidemiology of some zoonotic pathogens, such as hantaviruses, can be linked to the population dynamics of the rodent host. In this case, during an outbreak of the rodent host population many human infections may occur. In other rodent-borne zoonotic diseases such phenomena are not known and in many cases the rodent host specificity of a given pathogen is unclear. The monitoring of relevant rodent populations and of the rodent-borne zoonotic pathogens is essential to (1) understand the distribution and epidemiology of pathogens and (2) develop forecasting tools to predict outbreaks of zoonoses. Presently, there are no systematic long-term monitoring programs in place for zoonoses in Germany. Rodent monitoring activities are largely restricted to the plant protection sector, such as for the common vole (Microtus arvalis) and forest-damaging rodents. However, during the last 10–15 years a number of specific research projects have been initiated and run for a few years and Norway rat (Rattus norvegicus) monitoring has been implemented in Hamburg and Lower Saxony. Based on close cooperation of federal and state authorities and research institutions these efforts could be utilized to gain information about the distribution and importance of rodent-borne zoonoses. Nevertheless, for the integration of rodent population dynamics and zoonotic disease patterns and especially for developing predictive models, long-term monitoring is urgently required. To establish a systematic long-term monitoring program, existing networks and cooperation need to be used, additional collaborators (e.g., pest control operators) should be included and synergetic effects of different scientific fields should be utilized. © 2014, Springer-Verlag Berlin Heidelberg.


Borchert D.,Saarland University | Kohler P.,Bundesforschungsinstitut For Tiergesundheit | Jager T.,Paracelsus Medical University | Diederich M.,Bundesforschungsinstitut For Tiergesundheit | And 3 more authors.
Minimally Invasive Therapy and Allied Technologies | Year: 2014

Introduction: Operative time is an accepted risk factor for the development of postoperative ileus (POI). Innovative surgical procedures such as robotic surgery and natural orifice transluminal endoscopic surgery (NOTES) will be associated with longer operative times. Although intraabdominal manipulation is a major factor for POI the impact of prolonged capnoperitoneum on postoperative gastrointestinal transit time (GIT-TT) has rarely been studied. Material and methods: IRB approved survival pilot study to assess postoperative GIT-TT using fecal collection and chromium-oxide (Cr2O3) labeling in pigs. Twelve female pigs were randomly assigned to three groups of four animals each. Group A received eight hours anesthesia and pressure-controlled high flow capnoperitoneum (15 mmHg), group B eight hours of anesthesia only and group C no intervention. No intraoperative manipulation. The pilot study was terminated after eight days. Results: None of the animals developed POI. In Group A one animal died after eight hours of general anesthesia. No differences in postoperative fecal output, Cr2O3 excretion rate or weight gain were found. Conclusion: This study is the first to investigate eight hours of capnoperitoneum in a survival model. GIT-TT is not affected by prolonged capnoperitoneum in pigs. No POI occurred with prolonged capnoperitoneum. Prolonged capnoperitoneum is safe regarding postoperative gastrointestinal function in innovative surgical procedures. © 2014 Informa Healthcare.


Halle I.,Bundesforschungsinstitut For Tiergesundheit | Kluth H.,Martin Luther University of Halle Wittenberg | Danicke S.,Bundesforschungsinstitut For Tiergesundheit
Archiv fur Geflugelkunde | Year: 2012

The effects of a graded dietary protein and energy concentration were investigated on the growth performance of laying-type cockerels of different strains. A total of 378 male one-day chickens of Lohmann Tradition origin and 378 male one-day chickens of Lohmann Brown origin were allocated to 9 dietary treatments with 7 pens per group and 12 birds each for 49 days. A total of 9 treatment groups resulted from trifold crude protein (180/200/215 g/kg) and trifold energy (11/12/12.5 MJ AMEN/kg) grading in the diet. One N-balance trial with cockerels at the age of 3 weeks was carried out parallel to the growing trial. The daily weight gain of cockerels was improved at all protein and energy levels at 7 weeks of age. The highestbody weight gain of 825-846 g and 824-830 g, respectively were achieved with cockerels of the origin Lohmann Tradition and Lohmann Brown by feeding a diet with 215 g crude protein and 11-12 MJ AMEN per kg feed. The feedto- gain ratio of cockerels of origin Lohmann Tradition was significantly improved compared to cockerels of origin Lohmann Brown. The growth data were adapted on the basis of the Gompertz function. Maximum daily weight gain was reached by the laying-type cockerels at 49-67 days of age. Slaughter of cockerels at the age of 49 days resulted in carcass yield of 60-63%, breast meat yield of 7-8% and yield of 2 legs of 20%. The highest N-balance was measured in cockerels of groups with 200 g crude protein and 12 MJ AMEN per kg diet. The highest PPW (63.1) was calculated by groups with 180 g crude protein and 12.5 MJ AMEN per kg diet. It is concluded that intensive rearing of cocks of layer breeds Lohmann Tradition and Lohmann Brown may only result in a body weight of 800 g at the age of 49 days if the crude protein concentration in the diet is at least 21.5%. With diets containing 21.5% crude protein and 12.5 MJ AMEN/kg a feed conversion ratio of 2.02 kg/kg may be achieved. © Verlag Eugen Ulmer, Stuttgart.


Halle I.,Bundesforschungsinstitut For Tiergesundheit | Kluth H.,Martin Luther University of Halle Wittenberg | Danicke S.,Bundesforschungsinstitut For Tiergesundheit
Archiv fur Geflugelkunde | Year: 2013

The effects of a graded dietary protein and energy concentration were investigated on the growth performance of laying-type cockerels of different strains. A total of 378 male one-day chickens of Lohmann Tradition origin and 378 male one-day chickens of Lohmann Brown origin were allocated to 9 dietary treatments with 7 pens per group and 12 birds each for 49 days. A total of 9 treatment groups resulted from trifold crude protein (180/200/215 g/kg) and trifold energy (11/12/12.5 MJ AMEN/kg) grading in the diet. One N-balance trial with cockerels at the age of 3 weeks was carried out parallel to the growing trial. The daily weight gain of cockerels was improved at all protein and energy levels at 7 weeks of age. The highest body weight gain of 825-846 g and 824-830 g, respectively were achieved with cockerels of the origin Lohmann Tradition and Lohmann Brown by feeding a diet with 215 g crude protein and 11-12 MJ AMEN per kg feed. The feed-to-gain ratio of cockerels of origin Lohmann Tradition was significantly improved compared to cockerels of origin Lohmann Brown. The growth data were adapted on the basis of the Gompertz function. Maximum daily weight gain was reached by the laying-type cockerels at 49-67 days of age. Slaughter of cockerels at the age of 49 days resulted in carcass yield of 60-63%, breast meat yield of 7-8% and yield of 2 legs of 20%. The highest N-balance was measured in cockerels of groups with 200 g crude protein and 12 MJ AMEN per kg diet. The highest PPW (63.1) was calculated by groups with 180 g crude protein and 12.5 MJ AMEN per kg diet. It is concluded that intensive rearing of cocks of layer breeds Lohmann Tradition and Lohmann Brown may only result in a body weight of 800 g at the age of 49 days if the crude protein concentration in the diet is at least 21.5%. With diets containing 21.5% crude protein and 12.5 MJ AMEN/kg a feed conversion ratio of 2.02 kg/kg may be achieved. © Verlag Eugen Ulmer, Stuttgart.


PubMed | Bundesforschungsinstitut For Tiergesundheit
Type: Journal Article | Journal: Berliner und Munchener tierarztliche Wochenschrift | Year: 2011

In 2008 and 2009, two consecutive outbreaks of Q fever in humans were recorded in the district of Freudenstadt, northern Black Forrest, Baden-Wrttemberg, Germany. In 2008, a total of 41 persons from a single local community fell ill and were found infected with Coxiella burnetii. Although comprehensive diagnostic and epidemiological outbreak investigations were conducted and control measures taken which included vaccination of ruminants at risk in three parts of the affected community, re-occurrence of the disease in 2009 with further 29 confirmed human Q fever cases could not be prevented. While the origin of infection of the first outbreak was probably a flock of 550 sheep moved in the surrounding of the affected villages, the source of infection for the consecutive outbreak in 2009 could not be identified. It seems possible that meadows contaminated with infectious placenta or birth fluids represented the sources of infection.


PubMed | Bundesforschungsinstitut For Tiergesundheit
Type: Journal Article | Journal: Berliner und Munchener tierarztliche Wochenschrift | Year: 2011

Campylobacter fetus subsp. venerealis is the causative agent of bovine genital campylobacteriosis and is transmitted by asymptomatic carrier bulls via contaminated semen during artificial insemination. The aim of the present study was to determine the in vitro susceptibility of Campylobacter fetus subsp. venerealis isolated from bovine specimens in the years from 2000 to 2009 in Germany to antibiotics generally used in semen treatment. The susceptibilities of 50 strains to spectinomycin (10 microg), gentamicin (10 microg), streptomycin (25 microg), penicillin (10 microg), lincomycin (10 microg), ciprofloxacin (5 microg), erythromycin (30 microg) and tetracycline (30 microg) were determined using a disk diffusion susceptibility test. All strains were susceptible to gentamicin. A considerably reduced susceptibility to one or more antimicrobial agents was detected in seven out of 50 isolates (14%) with the most frequent reduction in susceptibility to lincomycin and spectinomycin. Furthermore, strains with reduced susceptibility to more than one antimicrobial agent were always associated with reduced susceptibility to lincomycin. It is recommended to determine the antimicrobial susceptibility of Campylobacter fetus subsp. venerealis isolates in order to evaluate the efficacy of the generally used antibiotic treatment of bull semen and to detect possible resistances.

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