Jhansi, India

Bundelkhand University

Jhansi, India

Bundelkhand University is a public university based in Jhansi, Uttar Pradesh, India. Founded in 1975, it has professional, technical and vocational study programmes along with facilities for research. Wikipedia.

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Nigam G.,Bundelkhand University | Sharma N.K.,Bundelkhand University
Indian Journal of Traditional Knowledge | Year: 2010

The paper describes 46 ethnoveterinary plants of Jhansi district of Uttar Pradesh. Plant species are reported along with plant parts and some local formulations used medicinally for the treatment of various animal diseases and disorders.

Sharma P.,Bundelkhand University | Huq A.U.,Bundelkhand University | Singh R.,Bundelkhand University
Journal of Human Reproductive Sciences | Year: 2014

Aims: The current study was to assess the protective role of resveratrol in cypermethrin-induced reproductive toxicity in male Wistar rats. Materials and Methods: Rats were exposed to cypermethrin (3.83 mg/kg bw) for 14 days. Pre- and post-treatment of resveratrol (20 mg/kg bw for 14 days) was given to cypermethrin exposed rats. At the end of the experiment, rats were sacrificed, testis and epididymis were removed, sperm characteristics, sex hormones, and various biochemical parameters were studied. Results: Cypermethrin exposure resulted in a significant decrease in weight of testis and epididymis, testicular sperm head counts, sperm motility and live sperm counts and increase in sperm abnormalities. Serum testosterone (T), follicle stimulating hormone (FSH), luteinizing hormone (LH), reduced glutathione (GSH), catalase (CAT), superoxide dismutase (SOD), glutathione S-transferase (GST), glutathione reductase (GR), glutathione peroxidase (GPx) and total protein (TP) content were decreased and lipid peroxidation (LPO) level was increased on cypermethrin exposure. Pre- and post-treatment of resveratrol increased sperm head counts, sperm motility, live sperm counts, T, FSH, LH, GSH, CAT, SOD, GST, GR, GPx and TP contents and decreased LPO. Treatment with resveratrol alone has improved sperm parameters and testicular antioxidant defence system. Conclusion: The study concluded that resveratrol ameliorated cypermethrin-induced testicular damage by reducing oxidative stress and by enhancing the level of sex hormones. © 2014 Journal of Human Reproductive Sciences.

Singh R.,Bundelkhand University | Sharma P.,Bundelkhand University
Toxicology International | Year: 2011

Lindane, an organochlorine pesticide, is recognized as a major public health concern because of its potential toxic effects on human health. Its persistence in the body fluids may lead to continuous blood circulation, liver exposure and hepatotoxicity. The present study was undertaken to evaluate the possible protective role of curcumin on lindane-induced hepatotoxicity. Forty-two healthy adult male Wistar rats were divided into seven groups of six rats each. Group I was given dimethylsulfoxide. A single dose of lindane (60 mg/kg bw) was given to group II. Lindane (30 mg/kg bw) was given daily to group III for 14 days. Treatment with curcumin (100 and 200 mg/kg) was given to groups IV and V before (pretreatment) and to groups VI and VII after (post-treatment) 14 days exposure of lindane. Oxidative stress parameters and antioxidative enzymes were investigated in the liver of exposed and treated rats. A significant increase in lipid peroxidation, and decrease in glutathione level, Superoxide dismutase catalase, glutathione-S-transferase, glutathione peroxidase, glutathione reductase and NADPH quinine reductase activities was observed in liver of rats exposed to lindane. Curcumin (Pre-and post-treatment) nearly normalized all these parameters. Histological alterations were also observed in the liver tissue after lindane exposure. Treatment with curcumin significantly prevented the lindane-induced histological alterations. In conclusion, curcumin has protective effect over lindane-induced oxidative damage in rat liver.

Singh V.K.,Bundelkhand University | Slabunov A.,Petrozavodsk State University
International Geology Review | Year: 2015

Analysis of 3.3 Ga tonalite-trondhjemite-granodiorite (TTG) series granitoids and greenstone belt assemblages from the Bundelkhand craton in central India reveal that it is a typical Archaean craton. At least two greenstone complexes can be recognized in the Bundelkhand craton, namely the (i) Central Bundelkhand (Babina, Mauranipur belts) and (ii) Southern Bundelkhand (Girar, Madaura belts). The Central Bundelkhand greenstone complex contains three tectonostratigraphic assemblages: (1) metamorphosed basic or metabasic, high-Mg rocks; (2) banded iron formations (BIFs); and (3) felsic volcanics. The first two assemblages are regarded as representing an earlier sequence, which is in tectonic contact with the felsic volcanics. However, the contact between the BIFs and mafic volcanics is also evidently tectonic. Metabasic high-Mg rocks are represented by amphibolites and tremolite-actinolite schists in the Babina greenstone belt and are comparable in composition to tholeiitic basalts-basaltic andesites and komatiites. They are very similar to the metabasic high-Mg rocks of the Mauranipur greenstone belt. Felsic volcanics occur as fine-grained schists with phenocrysts of quartz, albite, and microcline. Felsic volcanics are classified as calc-alkaline dacites, less commonly rhyolites. The chondrite-normalized rare earth element distribution pattern is poorly fractionated (LaN/LuN = 11-16) with a small negative Eu anomaly (Eu/Eu∗ = 0.68-0.85), being characteristic of volcanics formed in a subduction setting. On Rb - Y + Nb, Nb - Y, Rb - Ta + Yb and Ta - Yb discrimination diagrams, the compositions of the volcanics are also consistent with those of felsic rocks formed in subduction settings. SHRIMP-dating of zircon from the felsic volcanics of the Babina belt of the Central Bundelkhand greenstone complex, performed for the first time, has shown that they were erupted in Neoarchaean time (2542 ± 17 Ma). The early sequence of the Babina belt is correlatable with the rocks of the Mauranipur belt, whose age is tentatively estimated as Mesoarchaean. The Central Bundelkhand greenstone complex consists of two (Meso- and Neoarchaean) sequences, which were formed in subduction settings. © 2014 © 2014 Taylor & Francis.

Shrivastava S.,Bundelkhand University | Singh M.P.,Dr. B.R. Ambedkar University
Applied Soft Computing Journal | Year: 2011

This paper describes the performance evaluation for the feed forward neural network with three different soft computing techniques to recognition of hand written English alphabets. Evolutionary algorithms for the hybrid neural network are showing the numerous potential in the field of pattern recognition. We have taken five trials and two networks of each of the algorithm: back propagation, Evolutionary algorithm, and Hybrid Evolutionary algorithm respectively. These algorithms have been taken the definite lead on the conventional approaches of neural network for pattern recognition. It has been analyzed that the feed forward neural network by two Evolutionary algorithms makes better generalization accuracy in character recognition problems. The problem of not convergence the weight in conventional backpropagation has also eliminated by using the soft computing techniques. It has been observed that, there are more than one converge weight matrix in character recognition for every training set. The results of the experiments show that the hybrid evolutionary algorithm can solve challenging problem most reliably and efficiently. These algorithms have also been compared on the basis of time and space complexity for the training set. © 2010 Elsevier B.V. All rights reserved.

Preedip Balaji B.,Indian Statistical Institute | Kumar V.,Bundelkhand University
Library Hi Tech | Year: 2011

Purpose: This paper aims to discuss the present status of using new generation web technology, social media and Web 2.0 features among the technological university library websites in south India. It seeks to assess the library websites as a primary platform and one-stop portal for information services and to examine how much library websites are effective in providing web-based information services. Design/methodology/approach: The library websites of the technological universities in south India were evaluated on the basis of a relative weight checklist. The criteria for the checklist were drawn on the basis of availability of websites for library, resource discovery tools, access to scholarly content and Web 2.0 tools. The various issues and challenges in adapting new web technologies in the academic environment are discussed. Findings: Using the current web development technologies and deploying for mainstream web information services is not widespread as web information services are yet to take off widely in academic libraries. The majority of university libraries are found to be working in the conventional library settings and the diffusion rate of web information services is relatively low. Originality/value: As this is an assessment of the existing online information infrastructure facilities of the engineering universities in south India, the awareness of web-based information services, their viability, and service values can be enhanced. More emphasis to improve upon the current learning, online educational facilities and benchmarking electronic information services for sustainability is highlighted. © Emerald Group Publishing Limited.

Radhakrishna T.,Center for Earth Science Studies | Chandra R.,Bundelkhand University | Srivastava A.K.,Bundelkhand University | Balasubramonian G.,Center for Earth Science Studies
Precambrian Research | Year: 2013

Mafic dykes in the central Indian Bundelkhand and eastern Indian Bastar cratons are potential sources for tracing the location of the Indian shield within Palaeoproterozoic supercontinent reconstructions. A total of 610 oriented core samples were collected from 27 mafic dykes (342 samples) in Bundelkhand craton and 20 dykes (268 samples) in Bastar craton. The characteristic magnetisations identify distinct groups of directions. The derived palaeopoles are integrated with recently reported U-Pb isotopic ages from the Bundelkhand and Bastar cratons and correlated with palaeopoles from the mafic dykes in the Dharwar craton, South India. Characteristic remanence (ChRM) identified in these dykes are classified into (i) steep upward/downward components further sub-grouped as ca. 2.37Ga steep 1 (λ=10.2°S; F{cyrillic}=75.0°E; A95=18.1° in Bundelkhand and λ=22.3°N; F{cyrillic}=71.4°E; A95=21.6° in Bastar), component comparable with ca. 2.4-2.45Ga steep 2 group from one dyke in Bundelkhand (λ=14°S; F{cyrillic}=101°E; A95=26.1°) and one dyke in Bastar (λ=6°N; F{cyrillic}=113°E; A95=26.5°). A steep component (λ=60.4°N; F{cyrillic}=45.3°E; A95=9.7° in Bundelkhand and a comparable component λ=49°N; F{cyrillic}=129°E; A95=15.1° from one dyke in Bastar) is not assigned an age at present. (ii) ca. 2.18Ga shallow easterly and antipodal shallow westerly components (λ=0.4°S; F{cyrillic}=347°E; A95=21.6° in Bundelkhand and λ=18.0°N; F{cyrillic}=344.0°E; A95=8.1° in Bastar) and (iii) 1.99Ga shallow northwest and antipodal shallow southeast (λ=57.5°N; F{cyrillic}=309.0°E; A95=4.7° in Bundelkhand and λ=39°N; F{cyrillic}=321°E; A95=28° in Bastar). A group (iv) of ~2.2Ga northeast shallow components (λ=36.0°S; F{cyrillic}=357.0°E; A95=9.4°) is found only in the Bundelkhand craton. The distinct groups of palaeomagnetic pole determinations from dykes of the Bundelkhand and Bastar craton exhibit a remarkable match with palaeomagnetic poles determined from Precambrian mafic dykes in the Dharwar craton. The close comparison of mafic dyke magnetisations between the cratons suggests close proximity since 2.45-2.5Ga. Models suggesting amalgamation of crustal blocks along the Central Indian Tectonic Zone at 1.8Ga or a 1.0Ga collision along this zone to form Rodinia are untenable. Testing of proposed NeoArchaean-Palaeoproterozoic supercontinent reconstructions showing a north China-India linkage or India's close proximity to Slave craton to form a supercraton 'Sclavia' are not supported. Instead, the data are compatible placing India in close proximity to the Yilgarn block of Western Australia. © 2012 Elsevier B.V.

Verma R.K.,Bundelkhand University
Asian Pacific Journal of Tropical Biomedicine | Year: 2014

Objective: To explore and document the information regarding usage of ethnoveterinary medicinal plants utilized by rural farmers and traditional herbal healers for livestock healthcare in Tikamgarh District of Bundelkhnad, Central India. Methods: The remote villages of Tikamgarh district were regularly visited from July 2011 to June 2012. Following the methods of Jain and Goel (1995) information regarding the usage of ethnoveterinary medicinal plants was collected. Results: A total of 41 plant species in 39 genera and 25 families were used traditionally with various plant parts and their combinations for the treatment of more than 36 diseases in the studied area. Trees (17 species) were found to be the most used Ethnoveterinary medicinal plants followed by herbs (15 species), shrubs (6 species) and grasses (3) in descending order. The most common diseases cough, diarrhoea and fever were treated by 04 ethnoveterinary medicinal plant species. Conclusions: The present study recommended that the crop and medicinal plant genetic resources cannot be conserved and protected without conserving/managing of the agro-ecosystem or natural habitat of medicinal plants and the socio-cultural organization of the local people. The same may be applied to protect indigenous knowledge, related to the use of medicinal and other wild plants. Introduction of medicinal plants in degraded government and common lands could be another option for promoting the rural economy together with environmental conservation, but has not received attention in the land rehabilitation programs in this region. © 2014 by the Asian Pacific Journal of Tropical Biomedicine.

Kulhari H.,Bundelkhand University | Kulhari D.P.,Bundelkhand University | Prajapati S.K.,Bundelkhand University | Chauhan A.S.,Concordia University at Chicago
Molecular Pharmaceutics | Year: 2013

The aim of this investigation was to evaluate the in vivo potential of poly(amidoamine) dendrimers (PAMAM) based simvastatin (SMV) formulations as nanoscale drug delivery units for controlled release action of simvastatin. Drug-dendrimer complexes were prepared and characterized by Fourier transform infrared (FTIR) spectroscopy. In a pharmacodynamic study, the percent increase in cholesterol was less with PAMAM dendrimer formulations as compared to pure drug. The cholesterol level was increased to 20.92% with pure SMV, whereas it was 11.66% with amine dendrimer, 11.49% with PEGylated dendrimer, and 10.86% with hydroxyl dendrimer formulations. Reduction in the increase in triglyceride and low density lipoprotein level was also more prominent with the drug-dendrimer formulations. The order of increase in high density lipoprotein level was PEGylated PAMAM-SMV (4.04%) > PAMAM-amine-SMV (2.57%) > PAMAM-hydroxyl-SMV (1.48%) > pure SMV (1.09%). Dendrimer-SMV formulations showed better pharmacokinetic performances than pure SMV suspension. The peak plasma SMV concentration increased from 2.3 μg/mL with pure SMV to 3.8 μg/mL with dendrimer formulations. The dendrimer mediated formulation had 3-5 times more mean SMV residence time than pure SMV. Furthermore, SMV absorption and elimination rates were decreased significantly, showing controlled release of SMV from the dendrimer formulations. © 2013 American Chemical Society.

Sharma P.,Bundelkhand University | Singh R.,Bundelkhand University
Bulletin of Environmental Contamination and Toxicology | Year: 2010

The aim of this study was to explore the adverse effects of lindane pesticide on testes and epididymus weight, sperm head counts, sperm motility, abnormal changes in sperm morphology, biochemical changes in endogenous antioxidants and oxidative enzymes in male wistar rats as well as to assess ameliorating role of 'curcumin'. Rats were exposed daily to lindane (30 mg/kgbw) for 14 and 28 days and administered with curcumin (100 mg/kgbw) in pretreatment, post treatment and combination groups. We observed decrease (p < 0.001) in testes and cauda epididymus weight, decrease (p < 0.001) in testicular sperm head count, increase (p < 0.001) in abnormal tail morphology (headless tail, multiple tail, broken tail, coiled tail and bent tail), abnormal head morphology (excessive hook, amorphous head, pin head, short head, blunt hook and detached hook) and decrease (p < 0.001) in sperm motility after lindane exposure, as compared to control. There was (p < 0.01) decline in superoxide dismutase, catalase and glutathione-s-transferase activity on lindane exposure, however, no change (p > 0.05) was observed in glutathione level. Lipid peroxidation was (p < 0.01) enhanced on lindane exposure as compared to control. Curcumin administration was able to ameliorate lindane induced reproductive toxicity in pretreatment, post treatment and combination groups. The study indicated that even after 14 days of metabolism, toxic effects of lindane were evident. © 2010 Springer Science+Business Media, LLC.

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