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Dhaka, Bangladesh

Regmi N.,BIRDEM General Hospital | Al-Nahian S.,BSMMU
Journal of Nepal Health Research Council | Year: 2013

Adrenocortical carcinoma as a cause of Cushing's syndrome in a child is a rare occurrence. Functioning adrenal carcinomas are detected usually when they are small while non-functioning tumors are incidentally detected when they grow to a large size. Here we report a case of Cushing's syndrome due to large functioning adrenal carcinoma(>12 cm in size) in a 10 year old female child who presented with clinical features of Cushing's syndrome along with virilisation.A combination of biochemical laboratory reports along with radiological investigations followed by histopathology helped us to arrive at a proper diagnosis. The tumor was ressected and the patient showed clinical signs of improvement. However, the surgical margin showed invasion by the tumor making a likely possibility of recurrence in the near future. Source

Bhuiyan M.J.H.,Sina | Akhter L.,BSMMU
Bangladesh Journal of Medical Science | Year: 2014

Kikuchi-Fujimoto Disease (KFD) present with Dysphagia, fever and lymphadenopathy. A young adult Bangladeshi female presented with fever and cervical lymphadenopathy. Broad spectrum antibiotic (3rd generation oral cephalosphorin) were given but no improvement after one month. FNAC suggested non specific lymphadenitis. Later on excision biopsy of cervical lymph node was done and histopathology suggested KFD. Oral prednisolone was given showing improvement and no relapse was en-counted Awareness of this disorder by clinicians and pathologists will help misdiagnosis and inappropriate treatment. Source

Khatun S.,BSMMU
Mymensingh medical journal : MMJ | Year: 2012

The purpose of the present study was to investigate two years clinical outcome of patients having myofacial pain dysfunction syndrome (MPDS). A total of 50 patients (male: 15, Female: 35, age: raged from 20 to 65 years) were included for this study. Clinical diagnosis for the assessment of anxiety and depression of each patient was performed by Hospital anxiety and depression (HAD) scale. Patients were then received either one of the following treatments: Occlusion correction only (n=14), Muscle Relaxant + anti-depressant drug (n=26), Physiotherapy + antidepressant drug + muscle relaxant (n=6) and Appliance + muscle relaxant (n= 4). Following two years observation, it was revealed that the treatment was apparently successful in 95% case; only 5% case was not successful due to their irregular visit. It can be concluded that MPDS is not primarily related to occlusal factors and a complex psycho physiological mechanism is involved in this type of pain problems. Source

This cross sectional study was done to find out the level of hearing improvement in Type-I tympanoplasty with cortical mastoidectomy in tubotympanic chronic otitis media. Data were analyzed from 60 patients with audiometric studies with a minimum of 6 months follow up. Patients who under went tympanoplasty alone were kept in Group I, and who under went tympanoplasty with cortical mastoidectomy were kept in Group II. All patients prior to tympanoplasty were examined thoroughly after taking detailed history. On otoscopy, site and size of the tympanic membrane perforation, condition of the rest of the tympanic membrane, condition of the middle ear mucosa and the ossicles were noted. Tuning fork test, test for facial nerve integrity and fistulae test were performed. Hearing level was assessed by pure tone audiometry with masking. X-ray mastoid and X-ray paranasal sinuses were done to exclude local pathology. Surgical approaches were mostly post-auricular and in few cases it was per-meatal in Group I patient. Audiometric evaluation performed according to the International Organization for Standardization (ISO) standard. Hearing threshold measured at 250, 500, 1000, and 2000 Hz. Hearing improvement was assessed by closure of the air bone gap. Mean closure of air bone gap in Group I was 9.38 dB and in Group II it was 20.61 dB which was statistically significant (p<0.001). Improvement of hearing level was more in patient who underwent tympanoplasty with cortical mastoidectomy than those patients on whom only tympanoplasty was performed. Hearing gain is more in Type-1 tympanoplasty combining with Cortical Mastoidectomy than in Type-1 tympanoplasty alone in the patient's of tubotympanic otitis media. Source

Nasrin M.,Bangladesh Medical College | Miah M.R.A.,Bangabandhu Sheikh Mujib Medical University | Datta P.G.,BSMMU | Saleh A.A.,Bangabandhu Sheikh Mujib Medical University | And 2 more authors.
Bangladesh Medical Research Council Bulletin | Year: 2012

Tonsils are one of the important secondary lymphoid organ in immune system. It remains controversial whether tonsillectomy results in decreased serum immunoglobulin level. The purpose of this study was to observe the effect of tonsillectomy on humoral immunity parameters among the patients with tonsillar disease. Total group A 70 patients up to the age of 18 years, who were enrolled for tonsillectomy and 30 age matched children group B were included for comparative study. Serum IgG, IgM and IgA levels were measured in all 70 patients before tonsillectomy and in 56 patients who came for 1st follow-up after one month and 30 patients who came for 2nd follow up after three months of tonsillectomy. Serum IgG, IgM and IgA levels were also measured in group B children. Serum IgG, IgM and IgA levels in patients of group A did not show any significant difference in comparison to group B. One month after tonsillectomy the level of IgG was slightly decreased and IgM and IgA were increased compared to preoperative value but not statistically significant. All IgG, IgM and IgA were also not significantly altered in comparison to group B. Three months after tonsillectomy serum IgG, IgM and IgA level were found decreased in comparison to pre operative value and group B, among which difference of only IgG was significant. After tonsillectomy humoral parameters were found reduced but overall impact on humoral immune status was not significantly altered. Source

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