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Burnaby, Canada

The British Columbia Institute of Technology , is a public polytechnic institution of higher education located in Burnaby, British Columbia, Canada. The polytechnic has five campuses located in the Metro Vancouver region, with the main campus in Burnaby. There is also the aerospace campus in Richmond, the marine campus in the City of North Vancouver, the Great Northern Way, and Downtown campus in Vancouver. It is provincially chartered through legislation in the College and Institute Act.BCIT was first established as the British Columbia Vocational School in 1960. When BCIT opened its Burnaby campus in 1964, initial enrollment was 498 students. As of 2013, enrollment has grown to 17,453 full-time students and 29,224 part-time students. Since its foundation, the institution has been home to over 125,000 alumni. Wikipedia.


Wasan E.K.,British Columbia Institute of Technology
PLoS neglected tropical diseases | Year: 2010

To develop an oral formulation of amphotericin B (AmB) that is stable at the temperatures of WHO Climatic Zones 3 and 4 (30-43 °C) and to evaluate its efficacy in a murine model of visceral leishmaniasis (VL). The stability testing of four novel oral lipid AmB formulations composed of mono- and di-glycerides and pegylated esters (iCo-010 to iCo-013) was performed over 60 d and analyzed by HPLC-UV. In addition, the four formulations were incubated 4 h in fasted-state simulated intestinal fluid. AmB concentration was measured spectrophotometrically and emulsion droplet diameter was assessed by dynamic light scattering. Antileishmanial activity of iCo-010 was evaluated at increasing oral doses (2.5 to 10 mg/kg) in a murine model of VL. AmB stability in the lipid formulation (iCo-010) was >75% over 60 days. After 4 h in fasted-state simulated intestinal fluid, AmB concentration was >95%. iCo-010 demonstrated significant efficacy when orally administered to VL-infected mice bid for five days (inhibition of 99%, 98%, and 83% at 10, 5 and 2.5 mg/kg compared to the vehicle control). In addition, the qd dose of 20 mg/kg provided 96% inhibition compared to the vehicle control. The oral AmB formulation iCo-010 is stable at the temperatures of WHO Climatic Zones 3 and 4 (30-43 °C). iCo-010 showed excellent antileishmanial activity at both 10 mg/kg po bid for 5 days (<99% reduction in parasitic infection) and 20 mg/kg po qd for 5 days (95% inhibition when compared to control). Source


A single-laboratory validation study was conducted for the quantification of Rg1, Re, Rb1, Rc, Rb2, and Rd in Asian ginseng (Panax ginseng C.A. Meyer) and North American ginseng (Panax quinquefolius L.) raw materials and finished products by RPHPLC. The extraction with aqueous methanol was optimized for whole root, powdered extract, and finished product (raw, tablet, and capsule matrixes) test articles. Root materials were treated with base to hydrolyze acidic malonyl ginsenosides to their neutral counterparts. Calibration curves for each ginsenoside were linear over the following ranges (μg/g): 5-394 for Rg1, 15-1188 for Re, 39-2981 for Rb1, 6-499 for Rc, 5-406 for Rb2, and 7-600 for Rd, all having a coefficient of determination (r2) of =99.5%. The LOD for Rg1, Re, Rb1, Rc, Rb2, and Rd was determined to be 1.06, 1.25, 2.19, 1.24, 1.27, and 1.70 μg/mL, respectively. Quantitative determinations performed with eight test materials by two analysts over 3 days (n = 12) resulted in RSDr values that ranged from 1.11 to 7.61%. © 2012 Publishing Technology. Source


Farhangi H.,British Columbia Institute of Technology
IEEE Power and Energy Magazine | Year: 2010

Smart grid that allows pervasive control and monitoring is emerging as a convergence of information and communication technology with power system engineering. A smart grid accommodates a wide variety of generation options such as central, distributed, and mobile empowering consumers to interact with the energy management system to adjust energy use and reduce energy costs. A smart grid is a self-healing system that predicts looming failures and takes corrective action to avoid problems. A smart grid uses IT to continually optimize the use of its capital assets while minimizing operational costs. A smart microgrid network can operate in both grid-tied as well as islanded modes integrating the components including that it incorporates power plants capable of meeting local demand as well as feeding the unused energy back to the electricity grid and makes use of local and distributed power-storage capability. The advent of these smart microgrids and the degree of their interplay and integration will play vital role in rapidly escalating smart grid capabilities and requirements. Source


Chan C.C.V.,British Columbia Institute of Technology | Berube P.R.,University of British Columbia | Hall E.R.,University of British Columbia
Water Research | Year: 2011

Shear stress has been recognized as an important parameter in controlling particle back-transport from membrane surfaces. However, little is known of the relationship between transient shear conditions induced by air sparging and fouling control near membrane surfaces. In this paper, the different types of surface shear stress profiles that had beneficial effects on minimizing reversible surface fouling were examined. The relationship between different statistical shear parameters (e.g. time-averaged shear, standard deviation of shear and amplitude of shear) and fouling control that have been used by others were examined as well. It was found that the fouling rate for membranes subjected to transient shear conditions was lower than for membranes subjected to constant shear conditions. The magnitude, duration and frequency of the shear conditions were found to have an impact on the fouling rate of membranes. It was also found that although some statistical shear parameters could generally be used to relate shear and fouling, they were inadequate to relate surface shear stress to fouling, for all transient shear conditions examined. © 2011 Elsevier Ltd. Source


Farhangi H.,British Columbia Institute of Technology
IEEE Power and Energy Magazine | Year: 2014

Smart grid-related blogs, newsletters, and conferences have endured numerous debates and discussions around the issue of whether or not the smart grid is being integrated correctly. While most debates focus on approach, methodology, and the sequence of what needs to be done, there is insufficient discussion about what is actually meant by ?smart grid integration.? This article attempts to present a holistic view of smart grid integration and argues for the importance of developing system integration ?maps? based on a utility?s strategic smart grid road map. © 2014 IEEE. Source

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