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Brevard, NC, United States

Brevard College is a small, private, United Methodist, liberal arts college in Brevard, North Carolina, United States. The college currently grants the Bachelor of Arts, Bachelor of Science, or Bachelor of Music degree. Current enrollment is about 705 students. Wikipedia.

Cabin R.J.,Brevard College | Clewell A.,5974 Willows Bridge Loop | Ingram M.,University of Wisconsin - Madison | McDonald T.,Tein McDonald and Associates | Temperton V.,Institute of Chemistry and Dynamics of the Geosphere ICG 3
Restoration Ecology | Year: 2010

Developing and strengthening a more mutualistic relationship between the science of restoration ecology and the practice of ecological restoration has been a central but elusive goal of SERI since its inaugural meeting in 1989. We surveyed the delegates to the 2009 SERI World Conference to learn more about their perceptions of and ideas for improving restoration science, practice, and scientist/practitioner relationships. The respondents' assessments of restoration practice were less optimistic than their assessments of restoration science. Only 26% believed that scientist/practitioner relationships were "generally mutually beneficial and supportive of each other," and the "science-practice gap" was the second and third most frequently cited category of factors limiting the science and practice of restoration, respectively ("insufficient funding" was first in both cases). Although few faulted practitioners for ignoring available science, many criticized scientists for ignoring the pressing needs of practitioners and/or failing to effectively communicate their work to nonscientists. Most of the suggestions for bridging the gap between restoration science and practice focused on (1) developing the necessary political support for more funding of restoration science, practice, and outreach; and (2) creating alternative research paradigms to both facilitate on-the-ground projects and promote more mutualistic exchanges between scientists and practitioners. We suggest that one way to implement these recommendations is to create a "Restoration Extension Service" modeled after the United States Department of Agriculture's Cooperative Extension Service. We also recommend more events that bring together a fuller spectrum of restoration scientists, practitioners, and relevant stakeholders. © 2010 Society for Ecological Restoration International. Source

Kaufman K.M.,Center for Autoimmune Genomics and Etiology | Zhao J.,University of California at Los Angeles | Kelly J.A.,Oklahoma Medical Research Foundation | Hughes T.,Oklahoma Medical Research Foundation | And 44 more authors.
Annals of the Rheumatic Diseases | Year: 2013

Objectives: The Xq28 region containing IRAK1 and MECP2 has been identified as a risk locus for systemic lupus erythematosus (SLE) in previous genetic association studies. However, due to the strong linkage disequilibrium between IRAK1 and MECP2, it remains unclear which gene is affected by the underlying causal variant (s) conferring risk of SLE. Methods: We fine-mapped ≥136 SNPs in a ∼227 kb region on Xq28, containing IRAK1, MECP2 and seven adjacent genes (L1CAM, AVPR2, ARHGAP4, NAA10, RENBP HCFC1 and TMEM187), for association with SLE in 15 783 case-control subjects derived from four different ancestral groups. Results: Multiple SNPs showed strong association with SLE in European Americans, Asians and Hispanics at p<5×10-8 with consistent association in subjects with African ancestry. Of these, six SNPs located in the TMEM187-IRAK1-MECP2 region captured the underlying causal variant(s) residing in a common risk haplotype shared by all four ancestral groups. Among them, rs1059702 best explained the Xq28 association signals in conditional testings and exhibited the strongest p value in transancestral meta-analysis (p meta=1.3×10-27, OR=1.43), and thus was considered to be the most likely causal variant. The risk allele of rs1059702 results in the amino acid substitution S196F in IRAK1 and had previously been shown to increase NF-KB activity in vitro. We also found that the homozygous risk genotype of rs1059702 was associated with lower mRNA levels of MECP2, but not IRAK1, in SLE patients (p=0.0012) and healthy controls (p=0.0064). Conclusions: These data suggest contributions of both IRAK1 and MECP2 to SLE susceptibility. Source

Bell T.M.,College of Charleston | Bell T.M.,Brevard College | Strand A.E.,College of Charleston | Sotka E.E.,College of Charleston
Journal of Heredity | Year: 2014

Since the 1970s, water temperatures along the Atlantic seaboard of the United States have risen by an average of 0.5 °C in summer months and 2.2 °C in winter months. In response, the distribution and abundance of several nearshore species have changed dramatically, but no study has attempted to document whether estuarine populations have evolved greater thermal tolerance. Here, we re-examine the classic latitudinal cline at lactate dehydrogenase (LDH) in the killifish Fundulus heteroclitus that was originally described by Dennis Powers and associates from samples collected between 1970 and 1972. Laboratory and field evidences indicated that northern and southern isozymes at muscle LDH are locally adapted to cold and warm temperatures, respectively. Despite the potential for evolutionary response at this adaptive locus, we detected no significant shift of the LDH cline from 20 to 30 F. heteroclitus collected at each of 13 locations between the early 1970s and 2010. We conclude that the microevolution of LDH-mediated thermal tolerance has not occurred, that shifts in alleles are too incremental to be distinguished from random processes, or that F. heteroclitus uses phenotypic and genetic mechanisms besides LDH to respond to warmer waters. © 2014 The American Genetic Association 2014. All rights reserved. Source

Thaxton J.M.,University of Puerto Rico at Mayaguez | Thaxton J.M.,U.S. Department of Agriculture | Cordell S.,U.S. Department of Agriculture | Cabin R.J.,Brevard College | Sandquist D.R.,California State University, Fullerton
Restoration Ecology | Year: 2012

Invasive non-native species can create especially problematic restoration barriers in subtropical and tropical dry forests. Native dry forests in Hawaii presently cover less than 10% of their original area. Many sites that historically supported dry forest are now completely dominated by non-native species, particularly grasses. Within a grass-dominated site in leeward Hawaii, we explored the mechanisms by which non-native Pennisetum setaceum, African fountain grass, limits seedlings of native species. We planted 1,800 seedlings of five native trees, three native shrubs, and two native vines into a factorial field experiment to examine the effects of grass removal (bulldozed vs. clipped plus herbicide vs. control), shade (60% shade vs. full sun), and water (supplemental vs. ambient) on seedling survival, growth, and physiology. Both grass removal and shade independently increased survival and growth, as well as soil moisture. Seedling survival and relative growth rate were also significantly dependent on soil moisture. These results suggest that altering soil moisture may be one of the primary mechanisms by which grasses limit native seedlings. Grass removal increased foliar nitrogen content of seedlings, which resulted in an increase in leaf-level photosynthesis and intrinsic water use efficiency. Thus in the absence of grasses, native species showed increased productivity and resource acquisition. We conclude that the combination of grass removal and shading may be an effective approach to the restoration of degraded tropical dry forests in Hawaii and other ecologically similar ecosystems. © 2011 Society for Ecological Restoration International. Source

Burrack H.J.,North Carolina State University | Fernandez G.E.,North Carolina State University | Spivey T.,Brevard College | Kraus D.A.,North Carolina State University
Pest Management Science | Year: 2013

BACKGROUND: Drosophila suzukii, a pest of soft-skinned berries and stone fruits, has recently rapidly expanded its global range. The impacts of D. suzukii infestation and subsequent fruit damage in North America and Europe have been profound. The aim of the present work was to assess host selection of D. suzukii in the field and laboratory, with an emphasis on hosts commonly grown in the southeastern United States, where D. suzukii has been established since 2010. RESULTS: Raspberries were infested at a greater rate than blackberries in the field, and varieties within both species were infested at different rates. Primocane-fruiting blackberries were often the least heavily infested. Further, blackberries and raspberries grown under high tunnels were infested at lower rates than those grown outside. Fruit and artificial substrates with a lower surface penetration force were more heavily infested than firmer substrates in the laboratory; no eggs were laid in artificial substrates exceeding 52.00 cN surface penetration force. CONCLUSION: Infestation rates differ between species and varieties within species of Rubus in the southeastern United States. Fruit penetration force is one potential measure of host susceptibility, but host attractiveness will likely depend upon additional factors, such as soluble sugar content. © 2013 Society of Chemical Industry. Source

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