Br Ambedkar University
Br Ambedkar University
Sarla S.,Hemwati Nandan Bahuguna Garhwal University |
Tiwari Brijesh K.,Br Ambedkar University
International Journal of Pharmaceutical Sciences Review and Research | Year: 2016
Albizia lebbeck Linn (Fabaceae) is a medicinal herb used in the traditional health care system of Uttara khand (India). The present study reports the anticonvulsant activities in the ethanolic extracts of the leaves of Albizia lebbeck Linn on the rats, induced both chemically and electrically. The models chosen for the activity were Maximal Electroshock (MES) and Pentylenetetrazole (PTZ) induced convulsions in rats. The test dose studied were 200 and 400 mg/kg body weight orally of ethanolic extract of the plant. Acute toxicity studies show that the extract was nontoxic up to the recommended dose 2000mg/kg body weight orally as per OECD guideline no 423. In PTZ induced seizures, onset of clonic convulsions were studied while in MES model, reduction in the mean duration of extensor phase was noted. The ethanolic extracts showed anticonvulsant activities against both MES and PTZ animal models. © 2017, Global Research Online. All rights reserved.
Kulshrestha A.,Mahatma Gandhi Chitrakoot Gramoday University |
Raghubanshi B.P.S.,RVSKVV Krishi Vigyan Kendra |
Sen S.K.,Mahatma Gandhi Chitrakoot Gramoday University |
Kulshrestha A.,Br Ambedkar University |
Singh Y.K.,Mahatma Gandhi Chitrakoot Gramoday University
Indian Journal of Agricultural Research | Year: 2014
A study was conducted during 2009-10 to 2010-11 in Budhara watershed in Ambah block of Morena district to assess the impact of watershed programme.Positive and significant effect of watershed progrmme was noticed in the study. Area and productivity of remunerative crops like arhar and wheat significantly increased with a change in arable area, agricultural area, irrigated area, cropping intensity, and area of horticultural crops. However, the cattle population, major and micro soil nutrients and its availability was also increased as well as improved fodder availability.
Shukla S.K.,Sungkyunkwan University |
Nagpure A.S.,University of Minnesota |
Sharma R.,Indian Institute of Technology Roorkee |
Sharma D.,Br Ambedkar University |
Shukla R.N.,A.P.S. University
International Journal of Environmental Technology and Management | Year: 2013
The present study focuses on an impact assessment of the cement industry on various social, environmental and public health issues. During the study, various socio-environmental issues, such as sex ratio, literacy rate, availability of basic amenities, disease spectrum, land use pattern, crop production, drinking water quality and the effect of emissions on vegetation were thoroughly addressed. Finally, the study also suggests a viable solution for the sustainable development of the cement industry in the particular area. The results show that socio-economic status (e.g. sex ratio, literacy rate and basic amenities) of study area are comparatively below than national average and the people health condition is also poor in the vicinity. Substantial numbers of asthma and tuberculosis patients have been found in study area during field visit. Study also reveals that leaves of dominating plant species in the study area are suffering from necrosis/chlorosis disease. Copyright © 2013 Inderscience Enterprises Ltd.
Gupta R.,Br Ambedkar University |
Thakur B.,Br Ambedkar University |
Singh P.,National JALMA Institute for Leprosy and Other Mycobacterial Diseases |
Singh H.B.,National JALMA Institute for Leprosy and Other Mycobacterial Diseases |
And 4 more authors.
Indian Journal of Medical Research | Year: 2010
Background & objectives: Emergence of multi-drug resistant (MDR) and extensively-drug resistant (XDR) strains of Mycobacterium tuberculosis has further complicated the problem of tuberculosis (TB) control. Medicinal plants offer a hope for developing alternate medicines for the treatment of TB. The present study was done to evaluate in vitro anti-tubercular activity of five medicinal plants viz., Acalypha indica, Adhatoda vasica, Allium cepa, Allium sativum and Aloe vera.Methods: Aqueous extracts of leaves of A. indica, A. vasica, bulbs of A. cepa, cloves of A. sativum and pure gel of A. vera leaves, were tested in vitro for their activity against two MDR isolates (DKU-156 and JAL-1236), reference susceptible strain M. tuberculosis H37Rv as well as rapid grower mycobacterial pathogen M. fortuitum (TMC-1529) using Lowenstein Jensen (L-J) medium and colorimetric BacT/ALERT 3D system. Activity in L-J medium was evaluated by percentage inhibition which was calculated by mean reduction in number of colonies on extract containing as compared to extract free controls. Results: Extracts of all the five plants A. indica, A. vasica, A. cepa, A. sativum and A. vera exhibited anti-tuberculosis activity in L-J medium, the proportion of inhibition of these plants extract in respect mentioned above is 95, 32, 37, 72, 32 per cent, respectively for MDR isolate DKU-156 and 68, 86, 79, 72, 85 per cent, respectively for another MDR isolate JAL-1236, while for sensitive M. tuberculosis H37Rv, inhibition was found to be 68, 70, 35, 63 and 41 per cent, at 4 per cent v/v concentration in L-J medium. There was no inhibition against rapid grower M. fortuitum (TMC-1529). In BacT/ALERT also, extracts of these plants showed significant inhibition against M. tuberculosis. Interpretation & conclusions: Our findings showed that all these plants exhibited activity against MDR isolates of M. tuberculosis. While the anti-TB activity of A. vera, A. vasica and A. sativum against MDR isolates confirm earlier results, activity of the extracts of A. indica and A. cepa is reported for the first time. Further studies aimed at isolation and identification of active substances from the extracts which exhibited promising activities, need to be carried out.
Kumar R.,Br Ambedkar University |
Chandra N.,University of Delhi |
Tomar S.,Br Ambedkar University
Astrophysics and Space Science | Year: 2016
This paper deals with the role of triple encounters with low initial velocities and equal masses in the framework of statistical escape theory in two-dimensional space. This system is described by allowing for both energy and angular momentum conservation in the phase space. The complete statistical solutions (i.e. the semi-major axis ‘a’, the distributions of eccentricity ‘e’, and energy Eb of the final binary, escape energy Es of escaper and its escape velocity vs) of the system are calculated. These are in good agreement with the numerical results of Chandra and Bhatnagar (1999) in the range of perturbing velocities (Formula Presented) in two-dimensional space. The double limit process has been applied to the system. It is observed that when (Formula Presented) for all directions in two-dimensional space. © 2016, Springer Science+Business Media Dordrecht.