Simeoni O.,Bordeaux Institute of Technology |
Simeoni O.,Keio University |
Piras V.,Keio University |
Piras V.,University Paris - Sud |
And 2 more authors.
Gene | Year: 2015
Upon receiving antigens from the innate immune cells, CD4+ T cells differentiate into distinct effector cells. To probe the global responses of distinct effector cells, we analyzed transcriptome-wide expressions of Th1, Th2, Treg and Th17 using Pearson correlation, entropy and principal component analyses, with Th0 as a control. Although the global response of Th0 was quite distinct from Th17, surprisingly, it was highly similar to Th1, Th2 and Treg. Moreover, 8 major temporal groups consisting of 5704 differentially expressed genes were revealed for both Th0 and Th17. Gene functional enrichment analysis showed immune responses and metabolic processes were mainly activated between Th0 and Th17, while genes related to cell cycle and replication were differentially regulated. Moreover, we found the upregulation of several novel genes for Th0 and Th17. Overall, we deduce that Th0 is globally similar to Th1, Th2 and Treg. Our results indicate that Th0 is a differentiated state and, therefore, may not be used as a control cell type. © 2015 Elsevier B.V..
Paris V.,Bordeaux Institute of Technology |
Strizic T.,University of California at Santa Barbara |
Pusey J.,U.S. Army |
Byl K.,University of California at Santa Barbara
Proceedings of the American Control Conference | Year: 2016
Control efforts on dynamic gaits for legged systems traditionally focus on limit cycles and their stability. However, there are many practical situations where step-to-step variability is highly desirable, for example to achieve variable footholds or to recover and replan after perturbations. In this paper we present an effective, high-level switching control framework for overcoming terrain obstacles using the familiar A∗ algorithm to search a mesh over the reachable space for a given set of controllers. In support of this, we present new low-level control strategies for generating stable bounding with planar models of a spring-legged quadruped robot, and demonstrate their use crossing gaps in the terrain. © 2016 American Automatic Control Council (AACC).
Tran T.-T.-H.,Hanoi University of Science and Technology |
Le T.-L.,Hanoi University of Science and Technology |
Morel J.,Bordeaux Institute of Technology
2014 IEEE 5th International Conference on Communications and Electronics, IEEE ICCE 2014 | Year: 2014
In this paper, we present a novel fall detection system based on the Kinect sensor. The originalities of this system are two-fold. Firstly, based on the observation that using all joints to represent human posture is not pertinent and robust because in several human postures the Kinect is not able to track correctly all joints, we define and compute three features (distance, angle, velocity) on only several important joints. Secondly, in order to distinguish fall with other activities such as lying, we propose to use Support Vector Machine technique. In order to analyze the robustness of the proposed features and joints for fall detection, we have performed intensive experiments on 108 videos of 9 activities (4 falls, 2 falls like and 3 daily activities). The experimental results show that the proposed system is capable of detecting falls accurately and robustly. © 2014 IEEE.
Sun-Waterhouse D.,The New Zealand Institute for Plant and Food Research Ltd |
Luberriaga C.,The New Zealand Institute for Plant and Food Research Ltd |
Luberriaga C.,Bordeaux Institute of Technology |
Jin D.,The New Zealand Institute for Plant and Food Research Ltd |
And 3 more authors.
Food and Bioprocess Technology | Year: 2013
This study measures and compares the bioactive content and appearance attributes of juices, dietary fibres (DFs) and skin wastes of three apple genotypes (white fleshed (WF), pink fleshed (PF) and red fleshed (RF)). The juices of the PF and RF apples had more appealing and stable colours and much greater total extractable polyphenol content (TEPC) (RF had the highest, 3.40 mg catechin equivalent/mL juice) and vitamin C (PF had the highest, 14. 2 mg/100 mL juice), compared with the WF apple. DFs isolated from the three apples using aqueous and ethanolic methods varied in bioactive profiles as a function of genotype. The TEPC and antioxidant activity (AA) of the fibres decreased in the order of PF > RF > WF. The total DF (TDF) in the fibre obtained using the aqueous method decreased in the order of RF > PF > WF. The ethanolic method yielded higher neutral monosaccharide (NM) and slightly greater TDF contents than the aqueous method. More polyphenol species were detected in the PF fibres, especially those obtained using the aqueous method. The polyphenol content in the apple skin decreased in the order of RF > WF > PF, with PF having slightly more pectic polysaccharides. As a whole, the RF apple appeared to be the best genotype as the potential source for juice, fibre and skin waste extract (SWE) ingredients. The PF apple would be the second best genotype for juice and fibre ingredients. The skin of the RF and WF genotypes would provide a good source of polyphenols. There is potential for promoting RF and PF apple genotypes because of their excellent nutritional values. The aqueous fibre preparation method used herein containing no solvent treatment and freezing steps represents an industrial-scale cost-effective alternative to the conventional ethanolic methods used for producing DFs whilst retaining polyphenols. © 2011 Springer Science+Business Media, LLC.
Barthou D.,Bordeaux Institute of Technology |
Barthou D.,French Institute for Research in Computer Science and Automation |
Jeannot E.,French Institute for Research in Computer Science and Automation
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2014
We propose a new algorithm, called SPAGHETtI, for static scheduling tasks on an unbounded heterogeneous resources where resources belongs to different architecture (e.g. CPU or GPU). We show that this algorithm is optimal in complexity O(|E||A|2∈+∈|V||A|), where |E| is the number of edges, |V| the number of vertices of the scheduled DAG and |A| the number of architectures - usually a small value - and that it is able to compute the optimal makespan. Moreover, the number of resources to be used for executing the schedule is given by a linear time algorithm. When the resources are bounded we provide a method to reduce the number of necessary resources up to the bound providing a set of compromises between the makespan and the size of the infrastructure. © 2014 Springer International Publishing Switzerland.
Li J.,University of Nottingham |
Johnson C.M.,University of Nottingham |
Buttay C.,University of Lyon |
Sabbah W.,Bordeaux Institute of Technology |
Azzopardi S.,Bordeaux Institute of Technology
Journal of Materials Processing Technology | Year: 2015
3 mm × 3 mm dummy SiC dies with 100\200\200 nm thick Ti\W\Au metallization have simultaneously been attached using sintering of Ag nanoparticle paste on AlN-based direct bonded copper substrates with 5\0.1 μm thick NiP\Au finish. The effect of preparation and sintering parameters including time of drying the printed paste, sintering temperature and time, and pressure, on the average shear strength for multiple die attachments was investigated. The surfaces of the die attachments after the shear tests were observed and the individual shear strength values correlated with the "apparent" porosity and thicknesses of the corresponding die attachments (sintered layer). The results obtained are further discussed and compared with typical data reported in existing literature. Main conclusions include: (i) the present shear strength values and their variations are comparable with those reported for single die attachment samples, (ii) the effects of sintering parameters can be ascribed to the effectiveness of the organic content burnout and appropriate rate of growth and coalescence of the Ag nanoparticles during the sintering process, and (iii) thickness values of the sintered Ag die attachments may be taken as nondestructive measurements to monitor/evaluate the quality of die attachment during power electronic module manufacturing/assembly process. © 2014 The Authors.
Petit J.,Bordeaux Institute of Technology |
Dugue B.,Bordeaux Institute of Technology
Work | Year: 2012
In this paper we discuss the possibilities of acting on psychosocial risk (PSR) factors by modifying the way in which an organisation operates. On the basis of an ergonomic intervention in an insurance company, we were able to show that the health problems observed by the operators were mainly the result of their inability to produce work of quality. Next, our analyses revealed the links between poor perceived quality, production difficulties and the rigidity of the organisational structure. After setting up working groups to deal with production difficulties, we were able to identify and test an organisational form that was better adapted to managing day-to-day production constraints and which was ultimately better able to be attentive to individual difficulties which had given rise, in the long term, to intrapsychic conflicts. © 2012 - IOS Press and the authors. All rights reserved.
Youssef T.,University of Bordeaux 1 |
Woirgard E.,University of Bordeaux 1 |
Azzopardi S.,Bordeaux Institute of Technology |
Martineau D.,LABINAL Power Systems |
Meuret R.,LABINAL Power Systems
2015 16th International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems, EuroSimE 2015 | Year: 2015
This paper focuses on the thin Nickel layer thicknesses. Thermal and mechanical behaviors of these thin layers in a power module are investigated. An approach is shown in order to present an improved modeling by considering the effect of these thin layers and by reducing time computation. © 2015 IEEE.
Bosilca G.,Tennessee Technological University |
Bouteiller A.,Tennessee Technological University |
Danalis A.,Tennessee Technological University |
Faverge M.,Bordeaux Institute of Technology |
And 2 more authors.
Computing in Science and Engineering | Year: 2013
New high-performance computing system designs with steeply escalating processor and core counts, burgeoning heterogeneity and accelerators, and increasingly unpredictable memory access times call for one or more dramatically new programming paradigms. These new approaches must react and adapt quickly to unexpected contentions and delays, and they must provide the execution environment with sufficient intelligence and flexibility to rearrange the execution to improve resource utilization. The authors present an approach based on task parallelism that reveals the application's parallelism by expressing its algorithm as a task flow. This strategy allows the algorithm to be decoupled from the data distribution and the underlying hardware, since the algorithm is entirely expressed as flows of data. This kind of layering provides a clear separation of concerns among architecture, algorithm, and data distribution. Developers benefit from this separation because they can focus solely on the algorithmic level without the constraints involved with programming for current and future hardware trends. © 2013 IEEE.
PubMed | Bordeaux Institute of Technology
Type: | Journal: Work (Reading, Mass.) | Year: 2012
In this paper we discuss the possibilities of acting on psychosocial risk (PSR) factors by modifying the way in which an organisation operates. On the basis of an ergonomic intervention in an insurance company, we were able to show that the health problems observed by the operators were mainly the result of their inability to produce work of quality. Next, our analyses revealed the links between poor perceived quality, production difficulties and the rigidity of the organisational structure. After setting up working groups to deal with production difficulties, we were able to identify and test an organisational form that was better adapted to managing day-to-day production constraints and which was ultimately better able to be attentive to individual difficulties which had given rise, in the long term, to intrapsychic conflicts.