Merida, Venezuela

The Universidad Bolivariana de Venezuela is a state university in Venezuela founded in 2003 by decree of President Hugo Chávez.The UBV is a part of the Chávez government's "Mission Sucre" social programs, which aim to provide free higher education to the poor. Consequently, enrollment at the UBV is free and open to all, regardless of academic qualifications, prior education or even nationality. The government expects the student body to grow to 1 million by 2009, with more than 190 satellite classrooms throughout Venezuela. The education programme at the UBV is generally in line with Hugo Chávez's democratic socialist vision of a Latin American "Bolivarian Revolution". Opposition leader Julio Borges though, labels it a "thinly disguised propaganda factory that takes advantage of the country's most vulnerable citizens". However, others are more optimistic. Maria Ejilda Castellano, the rector of the Bolivarian University in Caracas, has said that the institution is designed to benefit the poor precisely by encouraging the open exchange of ideas. Castellano said that the Bolivarian University is based on UNESCO principles for education and that "The professional produced by this institution will work for the transformation of society. She will be a critical thinker who can stimulate others and generate questions." Wikipedia.

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Martinez D.R.,Bolivarian University of Venezuela | Leon Luna C.,Central University of Venezuela
38th Latin America Conference on Informatics, CLEI 2012 - Conference Proceedings | Year: 2012

This paper presents the experience in implementing the curriculum of the Training Program in Computer Science Degree for the Social Management of the Bolivarian University of Venezuela which is based on project-based learning as a means of integration of training university in accordance with the needs of the country. The axis modular curriculum is integrated into the basic unit, called the project, which develops permanently and continuously throughout the race, interacting with communities and institutions. The project includes training components of the axes that make up the curriculum to solve real problems, but of different complexity, throughout the race. © 2012 IEEE.

Alvarado Y.J.,Venezuelan Institute for Scientific Research | Ballestas-Barrientos A.,Venezuelan Institute for Scientific Research | Cubillan N.,Bolivarian University of Venezuela | Morales-Toyo M.,Venezuelan Institute for Scientific Research | And 2 more authors.
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy | Year: 2013

The preferential solvation of thiophene- and furan-2-carboxaldehyde phenylhydrazone derivatives in DMSO-water and DMSO-n-octanol mixtures has been studied using visible absorption spectroscopy with a previous characterization of the electronic transitions by Time-Dependent Density Functional Theory (TDDFT) and solvatochromic study in several solvents with different hydrogen-bond donor capacity. The results indicate that the phenylhydrazones are preferentially solvated by clusters of DMSO-water existing in the solvent mixture and the dielectric enrichment as preferential solvation mechanism was discarded. A relation between local DMSO concentration with nitro groups and the electronegativity of the heteroatom of the five-membered ring was found. For DMSO-1-octanol mixtures, the results showed no preferential solvation. © 2012 Elsevier B.V. All rights reserved.

Silva Artigas S.E.,Bolivarian University of Venezuela | Mendoza Y.U.,Central University of Venezuela
2014 International Conference on Lightning Protection, ICLP 2014 | Year: 2014

Human lightning causalities are undesirable discrete events that occur randomly in space and time and consist on human dangerous situations which are caused by a cloud to ground lightning strike leaving consequences ranging from a temporary or permanent disability condition to a fatality. The statistical analysis of data set of records related to these types of events is a powerful tool for pattern recognition processes on its behavioral that can help to reduce the uncertainty related with its random nature. On this paper is analyzed the time evolution of the occurrence of human lightning fatalities from a mathematical-probabilistic point of view, with the aim of discover time patterns on its behavioral and based on it develop mathematical models with the ability of reduced uncertainty description of the observed time behavioral. The proposed approach is based on the stochastic model know as Non-Homogeneous Poisson Process used in the analysis of stochastic counting and point processes. The statistical data analysis and model fitting are based on a method known as Multi- resolution Analysis. The proposed approach offer important time-type information about the occurrence of lightning fatalities that can help on a better understanding of the incidence of these events on public health. © 2014 IEEE.

PubMed | University of Carabobo, Central University of Venezuela, Venezuelan Institute for Scientific Research, Bolivarian University of Venezuela and University of Paris Descartes
Type: | Journal: BMC hematology | Year: 2016

Fibrin provides a temporary matrix at the site of vascular injury. The aims of the present work were (1) to follow fibrin formation and lysis onto the surface of human dermal microvascular endothelial cells (HMEC-1), and (2) to quantify the secretion of fibrinolytic components in the presence of fibrin.Fibrin clots at different fibrinogen concentrations were formed on top of (model 1) or beneath (model 2) the endothelial cells. Fibrin formation or lysis onto the surface of HMEC-1 cells, was followed by turbidity. Clot structure was visualized by laser scanning confocal microscopy (LSCM). The secretion of uPA and PAI-1 by HMEC-1 cells was quantified by ELISA.The rate of fibrin formation increased approximately 1.5-fold at low fibrinogen content (0.5 and 1mg/mL; p<0.05) compared to the condition without cells; however, it was decreased at 2mg/mL fibrinogen (p<0.05) and no differences were found at higher fibrinogen concentrations (3 and 5mg/mL). HMEC-1 retarded dissolution of clots formed onto their surface at 0.5 to 3mg/mL fibrinogen (p<0.05). Secretion of uPA was 13 10(-6) ng/mL per cell in the absence of RGD and 8 10(-6) ng/mL per cell in the presence of RGD, when clots were formed on the top of HMEC-1. However, the opposite was found when cells were grown over fibrin: 6 10(-6) ng/mL per cell without RGD vs. 17 10(-6) ng/mL per cell with RGD. The secretion of PAI-1 by HMEC-1 cells was unrelated to the presence of fibrin or RGD, 7 10(-6) g/mL per cell and 5 10(-6) g/mL per cell, for the apical (model 1) and basal clots (model 2), respectively.HMEC-1 cells influence fibrin formation and dissolution as a function of the fibrin content of clots. Clot degradation was accentuated at high fibrin concentrations. The secretion of fibrinolytic components by HMEC-1 cells seemed to be modulated by integrins that bind RGD ligands.

PubMed | Bolivarian University of Venezuela and Venezuelan Institute for Scientific Research
Type: | Journal: European journal of pain (London, England) | Year: 2016

Opioid effectiveness to treat cancer pain is often compromised by the development of tolerance and the occurrence of undesirable side effects, particularly during long-term treatment. Hence, the search for more efficient analgesics remains a necessity. The main goal of this study was to relieve neuropathic symptoms associated with tumour growth by administering the non-opioid analgesic dipyrone (DIP) alone or in combination with magnesium chloride (MgClMice were inoculated with a melanoma cell line (B16-BL6) in the left thigh and two protocols were used to evaluate the effect of DIP (270mg/kg), MgClDIP promoted antinociception only at the beginning of both protocols due to the development of tolerance. The combination DIP-MgClThese results suggest that DIP-MgClThis study shows a non-opioid analgesic combined with an adjuvant as a therapeutic option to treat cancer pain. The avoidance of antinociceptive tolerance when repeated administration is required, as well as tumor growth reduction, are additional advantages to be considered.

PubMed | Francisco de Miranda National Experimental University, Bolivarian University of Venezuela and Venezuelan Institute for Scientific Research
Type: Journal Article | Journal: Biomedica : revista del Instituto Nacional de Salud | Year: 2015

Lutzomyia evansi is a recognized vector of Leishmania infantum in Colombia and Venezuela.To describe and illustrate the morphological abnormalities in Lu. evansi females captured in a rural focus of visceral leishmaniasis in Trujillo, Venezuela.Phlebotomine sand flies were collected using CDC light traps, Shannon traps and aspiration in resting places. The identification was performed according to Young & Duncan (1994) and drawings were made using a microscope with camara lucida .Abnormalities in the cibarium of Lu. evansi were detected in 4 (0.12%) females of the 3,477 adults that were studied.Lutzomyia evansi can have uncommon morphological variants associated with an increase in the number of teeth in the cibarium and their arrangement, which may lead to errors in the taxonomic identification of anomalous specimens. The study of such deformities can serve to avoid taxonomic identification errors.

Mahmood Q.,International Development Research Center | Muntaner C.,University of Toronto | Muntaner C.,University Pompeu Fabra | del Valle Mata Leon R.,Bolivarian University of Venezuela | Perdomo R.E.,Bolivarian University of Venezuela
Globalizations | Year: 2012

The Venezuelan health reform Barrio Adentro (BA), initiated in 2003, aims to improve population health and promote popular participation. Access to healthcare has improved but the distinguishing feature of BA is participation by communities. Popular participation has been institutionalized through the formation of health committees and communal councils. We explored the challenges/barriers faced by these community groups in BA. A mixed-methods participatory methodology was used involving 31 participants selected through non-random purposive sampling from five Venezuelan states. Results indicate that implementation issues challenge participation. There is political will at the highest level but the opposition political parties, Venezuelan Medical Federation, and the private media oppose the reform. Public participation in state affairs is facilitated if there are popular arenas of participation that promote engagement of organized citizenry with the state and an ongoing interaction between state and civil society in order to radically transform the state. © 2012 Copyright Taylor and Francis Group, LLC.

Sandoval-Ruiz C.,Bolivarian University of Venezuela
Revista Facultad de Ingenieria | Year: 2012

This article presents the design of a Reed Solomon encoder circuit based on a concurrent LFCS - Linear Structure Concurrent Feedback - allowing the generation of code redundancy symbols in parallel, provided that you supply the k information symbols to encode simultaneously, the encoder provides at its output corresponding redundancy symbols. To achieve this development was generalized mathematical model describing the behavior of the encoder, the configuration was done in VHDL hardware description language of a Reed Solomon encoder, taking as case study the RS (7.3), the design was simulated validating the proposed operation, and finally the comparison of the encoder implementation between the sequential version and the version based on LFCS, obtaining a reduction of hardware components and optimizing the speed of response and power consumption. In conclusion, the proposed encoder design validates the concurrent model generalized from the correspondence with the architecture of LFCS.

Ramos L.,Bolivarian University of Venezuela
Computers and Industrial Engineering | Year: 2015

Achieving success in modern industry requires the orchestration of the stakeholders of the manufacturing process as well as accessing information distributed along the manufacturing network involved; this latter is a key factor. Many manufacturing approaches have appeared with the aim of speeding up the manufacturing process by means of accessing certain knowledge encoded in a way that makes it reusable. Ontologies and the Semantic Web are emerging technologies proposed for knowledge representation and reasoning, which tend to be adopted in the manufacturing domain in order to deal and to facilitate such tasks. However, we have identified that many of the shortcomings of the proposed technologies have been neglected by some authors, compromising the feasibility of including them into any proposed approach. In this study we aim at describing the most prominent approaches which relate manufacturing with knowledge representation. Furthermore some formal aspects of Ontology and Semantic Web technologies will be introduced, with the intention of present a general view that integrates research contributions which combine both approaches in an emerging approach called Semantic Manufacturing. © 2015 Elsevier Ltd. All rights reserved.

Silva Artigas S.E.,Bolivarian University of Venezuela
2012 31st International Conference on Lightning Protection, ICLP 2012 | Year: 2012

The characterization of lightning flash occurrence processes is key to risk analysis. Based on it, the degree of exposure of structures to direct lightning strikes can be determined, and thus, the level of protection required by the protection system can be properly set. Several studies attest that lightning flash occurrence is a natural phenomenon whose parameters vary in time and space. Looking in detail the process of occurrence leads to identification of features that allow classifying it as a member of the family of stochastic processes called counting processes. This paper offers a proposal to conceptualize the lightning flash occurrence as a Non Homogeneous Poisson type counting process, in contrast to other existing approaches which are based on the statistical concept of independent and identically distributed samples (iid) that is used in statistical inference of random variables. To justify the approach, a number of considerations is set out, including formal theoretical aspects in the field of probability and statistics, along with the analysis of the variability measure in the approach involving iid. Additionally, the paper also considers the question of statistical estimation and inference process of occurrence of lightning from the perspective of stochastic processes, offering methodological approaches that are considered useful in modeling as-Nonhomogeneous Poisson Process. © 2012 IEEE.

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