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Istanbul, Turkey

Boğaziçi University is a public university located on the European side of the Bosphorus strait in Istanbul, Turkey. It has four faculties and two schools offering undergraduate degrees, and six institutes offering graduate degrees. Founded in 1863, it is the first American higher education institution founded outside the United States, having strong ties to the American educational system through Robert College. Boğaziçi University consistently ranks highest in Turkey, having the most number of applicants via the YGS-LYS Turkish university entrance examinations. This allows Boğaziçi University to attract many of the highest scoring students; as well as having the most preferred applied science, education, engineering, and social science programs in Turkey. The language of instruction is English. Boğaziçi University is the only Turkish university among first 200 universities worldwide according to the Times Higher Education World University Rankings of 2013-2014. Wikipedia.

Demirel B.,Bogazici University
Critical Reviews in Environmental Science and Technology | Year: 2014

The author reviews the current state of recent microbial community studies conducted on lab-pilot-full scale agricultural biogas digesters fed with energy crops operated in mono-and codigestion modes with or without use of manure as cosubstrate. It is commonly concluded by researchers that methane (CH4) formation mostly resulted from conversion of hydrogen (H2) and carbon dioxide (CO2), rather than aceticlastic methanogenesis. Hydrogenotrophic methanogenesis seems to be the major pathway for formation of methane from energy crops in agricultural biogas digesters. © 2014 Taylor and Francis Group, LLC. Source

Ozansoy M.,Bogazici University
Molecular neurobiology | Year: 2013

Parkinson's disease (PD) is the second most common neurodegenerative disorder, defined by the presence of resting tremor, muscular rigidity, bradykinesia, and postural instability. PD is characterized by the progressive loss of dopaminergic neurons within the substantia nigra pars compacta of the midbrain. The neuropathological hallmark of the disease is the presence of intracytoplasmic inclusions, called Lewy bodies (LBs) and Lewy neurites (LNs), containing α-synuclein, a small protein which is widely expressed in the brain. The α-synuclein gene, SNCA, is located on chromosome 4q22.1; SNCA-linked PD shows an autosomal dominant inheritance pattern with a relatively early onset age, and it usually progresses rapidly. Three missense mutations, A53T, A30P, and E46K, in addition to gene multiplications of the SNCA have been described so far. Although it is clear that LBs and LNs contain mainly the α-synuclein protein, the mechanism(s) which leads α-synuclein to accumulate needs to be elucidated. The primary question in the molecular pathology of PD is how wild-type α-synuclein aggregates in PD, and which interacting partner(s) plays role(s) in the aggregation process. It is known that dopamine synthesis is a stressfull event, and α-synuclein expression somehow affects the dopamine synthesis. The aberrant interactions of α-synuclein with the proteins in the dopamine synthesis pathway may cause disturbances in cellular mechanisms. The normal physiological folding state of α-synuclein is also important for the understanding of pathological aggregates. Recent studies on the α-synuclein protein and genome-wide association studies of the α-synuclein gene show that PD has a strong genetic component, and both familial and idiopathic PD have a common denominator, α-synuclein, at the molecular level. It is clear that the disease process in Parkinson's disease, as in other neurodegenerative disorders, is very complicated; there can be several different molecular pathways which are responsible for diverse and possibly also unrelated functions inside the neuron, playing roles in PD pathogenesis. Source

Advanced oxidation processes based on the generation of reactive species including hydroxyl radicals are viable options in eliminating a wide array of refractory organic contaminants in industrial effluents. The assessment of transformation products and toxicity should be, however, the critical point that would allow the overall efficiency of advanced oxidation processes to be better understood and evaluated since some transformation products could have an inhibitory effect on certain organisms. This article reviews the most recent studies on transformation products and toxicity for evaluating advanced oxidation processes in eliminating classes of compounds described as "textile chemicals" from aqueous matrices and poses questions in need of further investigation. The scope of this paper is limited to the scientific studies with two classes of textile chemicals, namely chlorophenols and alkylphenol ethoxylates, whose use in textile industry is a matter of debate due to health risks to humans and harm to the environment. The article also raises the critical question: What is the state of the art knowledge on relationships between transformation products and toxicity?. © 2013 Elsevier Ltd. Source

Incel O.D.,Bogazici University
Computer Networks | Year: 2011

The ability of newer generations of commercially available radios used on the sensor nodes to tune their operating frequency over different channels provides an opportunity to alleviate the effects of interference and consequently improve the network performance. In this paper we investigate the use of multi-channel communication to improve the capacity of wireless sensor networks. We provide an extensive survey in the field together with discussing the research challenges. Initially, we focus on the capacity issues in wireless sensor networks and identify the limiting factors on the capacity improvements. Then, we provide a brief survey on multi-channel communication in wireless ad hoc networks, which share similar characteristics with wireless sensor networks, and next focus on the multi-channel communication in wireless sensor networks. According to this survey, we observe that many of the protocols do not properly address the challenges of multi-channel communication, such as the channel overlaps. Related to these issues, we point out the possible future research directions in the field and list the properties of a well-designed multi-channel protocol for wireless sensor networks. © 2011 Elsevier B.V. All rights reserved. Source

Sanyal A.,Bogazici University
Macromolecular Chemistry and Physics | Year: 2010

Reactive polymers are increasingly becoming materials of wide interest because they offer solutions to challenges in biomolecular immobilization, drug-delivery and enzyme modifications. The Diels-Alder (DA) cycloaddition and the retro Diels-Alder (rDA) cycloreversion reaction in combination enables synthesis of maleimide based reactive polymeric materials. Also, the DA cycloaddition offer a reagent-free 'click' reaction to construct various macromolecular architectures. Furthermore, the thermally reversible nature of the DA adducts makes them attractive building blocks for the design of thermoreversible materials. A discussion of some of the author's own research work in this area is presented in this article within the context of recent reports in polymer chemistry employing this reaction combo. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

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