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News Article | April 26, 2017
Site: globenewswire.com

Vi har gjort pæne fremskridt inden for vores strategiske prioriteter i 1. kvartal 2017. Som led i organisationsændringerne er vi i gang med at fokusere yderligere ressourcer til områder med højt vækstpotentiale samt til vækstmarkeder, og vi har fortsat vores store investeringer i forskning og udvikling samt teknologisk lederskab. Vi har også set god fremgang i vores innovationspipeline og har lanceret to nye løsninger inden for bioenergi og BioAg. Derudover indgik vi i marts et nyt strategisk samarbejde med Boehringer Ingelheim inden for probiotika til rugerier på fjerkræfarme.


News Article | April 26, 2017
Site: globenewswire.com

Vi har gjort pæne fremskridt inden for vores strategiske prioriteter i 1. kvartal 2017. Som led i organisationsændringerne er vi i gang med at fokusere yderligere ressourcer til områder med højt vækstpotentiale samt til vækstmarkeder, og vi har fortsat vores store investeringer i forskning og udvikling samt teknologisk lederskab. Vi har også set god fremgang i vores innovationspipeline og har lanceret to nye løsninger inden for bioenergi og BioAg. Derudover indgik vi i marts et nyt strategisk samarbejde med Boehringer Ingelheim inden for probiotika til rugerier på fjerkræfarme.


News Article | April 26, 2017
Site: globenewswire.com

Sales in Q1 grew by 3% organically and by 4% in DKK, mainly driven by Food & Beverages and Bioenergy. EBIT grew by 6%, and the EBIT margin improved by 0.7 percentage point to 27.0%. Adjusting for the extraordinary costs related to the lay-offs in January, the EBIT margin would have been around 29%. The outlook for 2017 is maintained. We have made solid progress on our strategic priorities in the first quarter of 2017. As part of the organizational changes, resources are being focused on high-growth opportunities and growth markets, and we have continued our significant investments in R&D and technology leadership. We have also made good progress in our innovation pipeline and launched two new solutions in Bioenergy and BioAg. Furthermore, in March we embarked on a new strategic collaboration with Boehringer Ingelheim in probiotics for poultry hatcheries. Peder Holk Nielsen, President & CEO of Novozymes, comments: “It’s been a good start to the year. The majority of our markets have developed well, and profitability was high. I’m pleased to see that we’re making progress on our strategic priorities, exemplified by the recent collaboration with Boehringer Ingelheim in probiotics for poultry hatcheries. Finally, our pipeline of new innovation is advancing. All in all: positive developments in Q1.”


Receive press releases from iHealthcareAnalyst, Inc.: By Email Pulmonary Drugs Market by Drug Class, Application, Distribution Channel and Forecast to 2021, Upcoming Research by iHealthcareAnalyst, Inc. Maryland Heights, MO, April 19, 2017 --( Browse Pulmonary Drugs Market by Drug Class (Anticholinergics, Antihistamines, Combination Drugs, Inhaled Corticosteroids, Long-Acting Beta2-Agonists, Short-Acting Beta2-Agonists, Vasodilators, Antibiotics, Antileukotrienes, Enzymes, MAbs), Application (Allergic Rhinitis, Asthma & COPD, Cystic Fibrosis, Pulmonary Arterial Hypertension, Others), Distribution Channel (Drug Stores, E-commerce, Hospital Pharmacies, Retail Pharmacies) and Forecast 2017-2021 at https://www.ihealthcareanalyst.com/report/pulmonary-drugs-market/ The global pulmonary drugs market segmentation is based on drug class (anticholinergics, antihistamines, combination drugs, inhaled corticosteroids, long-acting beta2-agonists, short-acting beta2-agonists, vasodilators, antibiotics, antileukotrienes, enzymes, MAbs), application (allergic rhinitis, asthma & COPD, cystic fibrosis, pulmonary arterial hypertension, others), distribution channel (drug stores, e-commerce, hospital pharmacies, retail pharmacies). Major players operating in the global pulmonary drugs market and profiled in this report include Actelion Pharmaceuticals, Inc., AstraZeneca plc, Bayer AG, Boehringer Ingelheim GmbH, F. Hoffmann-La Roche Ltd., GlaxoSmithKline plc, Merck & Co., Inc., Novartis AG, Sunovion Pharmaceuticals, Inc., and Teva Pharmaceutical Industries Ltd. 1. Drug Class 1.1. Anticholinergics 1.2. Antihistamines 1.3. Combination Drugs 1.4. Inhaled Corticosteroids (ICS) 1.5. Long-Acting Beta2-Agonists (LABA) 1.6. Short-Acting Beta2-Agonists (SABA) 1.7. Vasodilators 1.8. Others (Antibiotics, Antileukotrienes, Enzymes, MAbs, etc.) 2. Application 2.1. Allergic Rhinitis 2.2. Asthma & COPD 2.3. Cystic Fibrosis 2.4. Pulmonary Arterial Hypertension 2.5. Others 3. Distribution Channel 3.1. Drug Stores 3.2. E-commerce 3.3. Hospital Pharmacies 3.4. Retail Pharmacies 4. Geography (Region, Country) 4.1. North America (U.S., Canada) 4.2. Latin America (Brazil, Mexico, Rest of LA) 4.3. Europe (U.K., Germany, France, Italy, Spain, Rest of EU) 4.4. Asia Pacific (Japan, China, India, Rest of APAC) 4.5. Rest of the World 5. Company Profiles 5.1. Actelion Pharmaceuticals, Inc. 5.2. AstraZeneca plc 5.3. Bayer AG 5.4. Boehringer Ingelheim GmbH 5.5. F. Hoffmann-La Roche Ltd. 5.6. GlaxoSmithKline plc 5.7. Merck & Co., Inc. 5.8. Novartis AG 5.9. Sunovion Pharmaceuticals, Inc. 5.10. Teva Pharmaceutical Industries Ltd. To request Table of Contents and Sample Pages of this report visit: https://www.ihealthcareanalyst.com/report/pulmonary-drugs-market/ About Us iHealthcareAnalyst, Inc. is a global healthcare market research and consulting company providing market analysis, and competitive intelligence services to global clients. The company publishes syndicate, custom and consulting grade healthcare reports covering animal healthcare, biotechnology, clinical diagnostics, healthcare informatics, healthcare services, medical devices, medical equipment, and pharmaceuticals. In addition to multi-client studies, we offer creative consulting services and conduct proprietary single-client assignments targeted at client’s specific business objectives, information needs, time frame and budget. Please contact us to receive a proposal for a proprietary single-client study. Contact Us iHealthcareAnalyst, Inc. 2109, Mckelvey Hill Drive, Maryland Heights, MO 63043 United States Email: sales@ihealthcareanalyst.com Website: https://www.ihealthcareanalyst.com Maryland Heights, MO, April 19, 2017 --( PR.com )-- The global pulmonary drugs market report provides market size (Revenue USD Million 2014 to 2021), market share, trends and forecasts growth trends (CAGR%, 2017 to 2021). The global pulmonary drugs market research report is further segmented by geography into North America (U.S., Canada), Latin America (Brazil, Mexico, Rest of LA), Europe (U.K., Germany, France, Italy, Spain, Rest of EU), Asia Pacific (Japan, China, India, Rest of APAC), and Rest of the World. The global pulmonary drugs market report also provides the detailed market landscape (market drivers, restraints, opportunities), market attractiveness analysis and also tracks the major competitors operating in the market by company overview, financial snapshot, key products, technologies and services offered, market share analysis and recent trends in the global market.Browse Pulmonary Drugs Market by Drug Class (Anticholinergics, Antihistamines, Combination Drugs, Inhaled Corticosteroids, Long-Acting Beta2-Agonists, Short-Acting Beta2-Agonists, Vasodilators, Antibiotics, Antileukotrienes, Enzymes, MAbs), Application (Allergic Rhinitis, Asthma & COPD, Cystic Fibrosis, Pulmonary Arterial Hypertension, Others), Distribution Channel (Drug Stores, E-commerce, Hospital Pharmacies, Retail Pharmacies) and Forecast 2017-2021 at https://www.ihealthcareanalyst.com/report/pulmonary-drugs-market/The global pulmonary drugs market segmentation is based on drug class (anticholinergics, antihistamines, combination drugs, inhaled corticosteroids, long-acting beta2-agonists, short-acting beta2-agonists, vasodilators, antibiotics, antileukotrienes, enzymes, MAbs), application (allergic rhinitis, asthma & COPD, cystic fibrosis, pulmonary arterial hypertension, others), distribution channel (drug stores, e-commerce, hospital pharmacies, retail pharmacies).Major players operating in the global pulmonary drugs market and profiled in this report include Actelion Pharmaceuticals, Inc., AstraZeneca plc, Bayer AG, Boehringer Ingelheim GmbH, F. Hoffmann-La Roche Ltd., GlaxoSmithKline plc, Merck & Co., Inc., Novartis AG, Sunovion Pharmaceuticals, Inc., and Teva Pharmaceutical Industries Ltd.1. Drug Class1.1. Anticholinergics1.2. Antihistamines1.3. Combination Drugs1.4. Inhaled Corticosteroids (ICS)1.5. Long-Acting Beta2-Agonists (LABA)1.6. Short-Acting Beta2-Agonists (SABA)1.7. Vasodilators1.8. Others (Antibiotics, Antileukotrienes, Enzymes, MAbs, etc.)2. Application2.1. Allergic Rhinitis2.2. Asthma & COPD2.3. Cystic Fibrosis2.4. Pulmonary Arterial Hypertension2.5. Others3. Distribution Channel3.1. Drug Stores3.2. E-commerce3.3. Hospital Pharmacies3.4. Retail Pharmacies4. Geography (Region, Country)4.1. North America (U.S., Canada)4.2. Latin America (Brazil, Mexico, Rest of LA)4.3. Europe (U.K., Germany, France, Italy, Spain, Rest of EU)4.4. Asia Pacific (Japan, China, India, Rest of APAC)4.5. Rest of the World5. Company Profiles5.1. Actelion Pharmaceuticals, Inc.5.2. AstraZeneca plc5.3. Bayer AG5.4. Boehringer Ingelheim GmbH5.5. F. Hoffmann-La Roche Ltd.5.6. GlaxoSmithKline plc5.7. Merck & Co., Inc.5.8. Novartis AG5.9. Sunovion Pharmaceuticals, Inc.5.10. Teva Pharmaceutical Industries Ltd.To request Table of Contents and Sample Pages of this report visit:https://www.ihealthcareanalyst.com/report/pulmonary-drugs-market/About UsiHealthcareAnalyst, Inc. is a global healthcare market research and consulting company providing market analysis, and competitive intelligence services to global clients. The company publishes syndicate, custom and consulting grade healthcare reports covering animal healthcare, biotechnology, clinical diagnostics, healthcare informatics, healthcare services, medical devices, medical equipment, and pharmaceuticals.In addition to multi-client studies, we offer creative consulting services and conduct proprietary single-client assignments targeted at client’s specific business objectives, information needs, time frame and budget. Please contact us to receive a proposal for a proprietary single-client study.Contact UsiHealthcareAnalyst, Inc.2109, Mckelvey Hill Drive,Maryland Heights, MO 63043United StatesEmail: sales@ihealthcareanalyst.comWebsite: https://www.ihealthcareanalyst.com Click here to view the list of recent Press Releases from iHealthcareAnalyst, Inc.


News Article | April 25, 2017
Site: www.prnewswire.co.uk

Certain financial information for 2017 and 2016 is presented on both a reported and a non-GAAP basis. Some numbers in this press release may not add due to rounding. Reported results were prepared in accordance with generally accepted accounting principles (GAAP) and include all revenue and expenses recognized during the periods. Non-GAAP measures exclude the items described in the reconciliation tables later in the release. The company's 2017 financial guidance is also being provided on both a reported and a non-GAAP basis. The non-GAAP measures are presented to provide additional insights into the underlying trends in the company's business. "Lilly's new product launches, including Trulicity and Taltz, led the company to a strong quarter of volume-driven revenue growth. We achieved this growth while maintaining our commitment to expand margins and improve productivity," said David A. Ricks, Lilly's president and CEO. "The progress we made in the first quarter continues the positive momentum we've built over the past few years. We remain on track to sustain a steady flow of innovation that has the potential to improve patients' lives and create value for shareholders." Key Events Over the Last Three Months The company and Boehringer Ingelheim launched Synjardy® XR (empagliflozin and metformin hydrochloride extended-release) tablets in the U.S. for adults with type 2 diabetes. Synjardy is part of the company's alliance with Boehringer Ingelheim. Regulatory With respect to Olumiant® (baricitinib) on which we collaborate with Incyte: The European Commission granted marketing authorization for 4 mg and 2 mg film-coated tablets in the European Union for the treatment of moderate-to-severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to, one or more disease-modifying antirheumatic drugs. Olumiant has been launched in select European countries. The U.S. Food and Drug Administration (FDA) issued a complete response letter for the New Drug Application (NDA) of baricitinib, an investigational medication for the treatment of moderate-to-severe rheumatoid arthritis, indicating that the FDA is unable to approve the application in its current form. The FDA specifically stated that additional clinical data are needed to determine the most appropriate doses and to further characterize safety concerns across treatment arms. The European Commission approved an update to the Synjardy label to include a change to the indication statement and inclusion of data on the reduction of risk of cardiovascular death in patients with type 2 diabetes and established cardiovascular disease when treated with empagliflozin. The FDA approved updates to the label for Trulicity® (dulaglutide) to include use in combination with basal insulin for adults with type 2 diabetes. Clinical With respect to Phase 3 trials of abemaciclib, a cyclin-dependent kinase (CDK)4 and CDK6 inhibitor, being tested in women with hormone-receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer: The company announced that abemaciclib, in combination with fulvestrant, in women who have relapsed or progressed after endocrine therapy was superior to fulvestrant plus placebo on progression-free survival. Lilly intends to initiate global submissions of these results, as well as for single-agent abemaciclib based on a previous Phase 2 study, beginning in the second quarter of 2017. The company announced results of a preplanned interim analysis, evaluating abemaciclib, in combination with an aromatase inhibitor (letrozole or anastrozole), compared to treatment with an aromatase inhibitor plus placebo. The trial met its primary endpoint of demonstrating statistically significant improvement in progression-free survival. In addition, improvement was shown in a key secondary endpoint of objective response rate. Lilly intends to begin global submissions of these results in the third quarter of 2017. The company announced that patients with moderate-to-severe plaque psoriasis treated with Taltz® (ixekizumab) demonstrated superior efficacy at 24 weeks compared to patients treated with Stelara® (ustekinumab). Business Development/Other The company completed its acquisition of CoLucid Pharmaceuticals. As a result of this acquisition, lasmiditan, in development for the acute treatment of migraine, has been added to Lilly's Phase 3 pipeline. The Japan IP High Court confirmed the decisions of the Japan Patent Office and ruled in Lilly's favor in the invalidation trials initiated by Sawai regarding Lilly's vitamin regimen patents for Alimta® (pemetrexed disodium). The company announced plans to invest $850 million in its U.S. operations in 2017. The company's investments span facilities across its U.S. enterprise, including research laboratories, manufacturing sites, and general and administrative areas. The investments are being driven by demand for Lilly products, as well as the company's robust pipeline of potential medicines in development targeting cancer, pain, diabetes and other unmet medical needs. First-Quarter Reported Results In the first quarter of 2017, worldwide revenue was $5.228 billion, an increase of 7 percent compared with the first quarter of 2016. The revenue increase was driven by an 8 percent increase due to volume, partially offset by a 1 percent decrease due to the unfavorable impact of foreign exchange rates. The increase in worldwide volume was largely due to 9 percent pharmaceutical growth driven by Trulicity, Taltz and other new products including Cyramza®, LartruvoTM, Basaglar® and Jardiance®. To a lesser extent, the increase in volume was also driven by companion animal products due to the inclusion of $40.8 million in revenue from the acquisition of Boehringer Ingelheim Vetmedica's U.S. feline, canine and rabies vaccine portfolio. These total volume increases were partially offset by decreased volumes for Zyprexa® and Alimta®. Revenue in the U.S. increased 15 percent, to $2.934 billion, driven primarily by increased volumes for Trulicity, Taltz, Lartruvo and companion animal products due to the inclusion of revenue from the acquisition of Boehringer Ingelheim Vetmedica's U.S. feline, canine and rabies vaccine portfolio, partially offset by decreased volume for Alimta. Realized prices increased U.S. revenue by 3 percent, primarily driven by Humalog®, which had significant unfavorable changes to rebates and discounts in the first quarter of 2016 that did not recur in the first quarter of 2017. Revenue outside the U.S. decreased 1 percent, to $2.295 billion, due to lower realized prices and volume from the loss of exclusivity for several products including Cymbalta® in Canada and Europe, Zyprexa in Japan and Alimta in numerous countries, as well as the unfavorable impact of foreign exchange rates. These were largely offset by increased volume for several newly launched pharmaceutical products, including Trulicity and Cyramza. Gross margin increased 10 percent, to $3.901 billion, in the first quarter of 2017 compared with the first quarter of 2016. Gross margin as a percent of revenue was 74.6 percent, an increase of 1.8 percentage points compared with the first quarter of 2016. The increase in gross margin percent was primarily due to manufacturing efficiencies. Operating expenses in the first quarter of 2017, defined as the sum of research and development, and marketing, selling and administrative expenses, were $2.783 billion, an increase of 3 percent compared with the first quarter of 2016. Research and development expenses increased 1 percent, to $1.238 billion, or 23.7 percent of revenue. Marketing, selling and administrative expenses increased 5 percent, to $1.545 billion, due to increased expenses related to new pharmaceutical products, partially offset by decreased expenses related to late life-cycle products. Operating expenses were 53.2 percent of revenue in the first quarter of 2017, a reduction of 2.2 percentage points compared with the first quarter of 2016. In the first quarter of 2017, the company recognized an acquired in-process research and development charge of $857.6 million associated with the acquisition of CoLucid Pharmaceuticals. There were no acquired in-process research and development charges in the first quarter of 2016. In the first quarter of 2017, the company recognized asset impairment, restructuring and other special charges of $213.9 million, primarily related to severance costs incurred as a result of actions taken to reduce the company's cost structure, as well as integration costs related to the acquisition of Novartis Animal Health. In the first quarter of 2016, the company recognized asset impairment, restructuring and other special charges of $131.4 million, composed of asset impairments related to the closure of an animal health manufacturing facility in Ireland and integration costs related to the acquisition of Novartis Animal Health. Operating income in the first quarter of 2017 was $46.1 million, a decrease of $669.7 million compared with the first quarter of 2016, primarily driven by an acquired in-process research and development charge for the acquisition of CoLucid Pharmaceuticals, partially offset by revenue growth. Other income (expense) was income of $15.1 million in the first quarter of 2017, compared with expense of $149.0 million in the first quarter of 2016. Other expense in the first quarter of 2016 was driven by a $203.9 million charge related to the impact of the Venezuelan financial crisis. During the first quarter of 2017, the company incurred $172.0 million of income tax expense, despite earning $61.2 million of income before income taxes, as a result of the nondeductible $857.6 million acquired in-process research and development charge for the acquisition of CoLucid Pharmaceuticals. During the first quarter of 2016, the company's effective tax rate was 22.4 percent. In the first quarter of 2017, net income (loss) and earnings (loss) per share were $(110.8) million and $(0.10), respectively, compared with $440.1 million and $0.41, respectively, in the first quarter of 2016. These decreases in net income (loss) and earnings (loss) per share were primarily driven by lower operating income, partially offset by higher other income. On a non-GAAP basis, first quarter 2017 gross margin increased 10 percent, to $4.085 billion. Gross margin as a percent of revenue was 78.1 percent, an increase of 1.8 percentage points compared with the first quarter of 2016. The increase in gross margin percent was primarily due to manufacturing efficiencies. Operating expenses were 53.2 percent of revenue in the first quarter of 2017, a reduction of 2.2 percentage points compared with the first quarter of 2016. Operating income increased $284.4 million, or 28 percent, to $1.304 billion in the first quarter of 2017, due to revenue growth, partially offset by higher operating costs related to new products. The effective tax rate was 21.2 percent in the first quarter of 2017, compared with 17.9 percent in the first quarter of 2016. The higher effective tax rate for the first quarter of 2017 was primarily due to a net discrete tax benefit of approximately $50 million in 2016. In the first quarter of 2017, net income and earnings per share increased 18 percent, to $1.040 billion, and $0.98, respectively, compared with $882.3 million, and $0.83, respectively, in the first quarter of 2016. The increases in net income and earnings per share were primarily driven by higher operating income, partially offset by a higher effective tax rate and lower other income. For further detail of non-GAAP measures, see the reconciliation below as well as the Reconciliation of GAAP Reported to Selected Non-GAAP Adjusted Information table later in this press release. For the first quarter of 2017, worldwide Humalog revenue increased 17 percent compared with the first quarter of 2016, to $708.4 million. Revenue in the U.S. increased 24 percent, to $449.1 million, primarily driven by decreased revenue in the first quarter of 2016 resulting from changes in estimates for rebates and discounts, and to a lesser extent increased demand. Revenue outside the U.S. increased 6 percent, to $259.4 million, driven by increased volume and, to a lesser extent, higher realized prices, partially offset by the unfavorable impact of foreign exchange rates. For the first quarter of 2017, worldwide Cialis revenue decreased 7 percent, to $533.6 million. U.S. revenue of Cialis was $296.7 million in the first quarter, an 8 percent decrease compared with the first quarter of 2016, driven by decreased demand. Revenue of Cialis outside the U.S. decreased 6 percent, to $236.9 million, driven by decreased volume and, to a lesser extent, the unfavorable impact of foreign exchange rates, partially offset by higher realized prices. For the first quarter of 2017, Alimta generated worldwide revenue of $489.9 million, which decreased 13 percent compared with the first quarter of 2016. U.S. revenue of Alimta decreased 14 percent, to $227.3 million, driven by decreased demand due to competitive pressure. Revenue outside the U.S. decreased 13 percent, to $262.6 million, driven by lower realized prices, the loss of exclusivity in several countries and, to a lesser extent, the unfavorable impact of foreign exchange rates. First-quarter 2017 worldwide revenue for Forteo was $347.5 million, a 9 percent increase compared with the first quarter of 2016. U.S. revenue increased 20 percent, to $177.7 million, driven by higher realized prices and, to a lesser extent, wholesaler buying patterns. Revenue outside the U.S. remained flat at $169.8 million, driven by lower realized prices, offset by increased volume. Worldwide Humulin revenue for the first quarter of 2017 decreased 12 percent compared with the first quarter of 2016 to $314.5 million. U.S. revenue decreased 14 percent, to $205.4 million, driven by a change in the estimate in 2016 for a government rebate, which increased revenue in that period, and to a lesser extent, decreased demand. Revenue outside the U.S. decreased 6 percent, to $109.1 million, driven by lower realized prices and, to a lesser extent, the unfavorable impact of foreign exchange rates, partially offset by increased volume. First-quarter 2017 worldwide Trulicity revenue was $372.9 million. U.S. revenue was $296.3 million, driven by growth in the GLP-1 market and increased share of market for Trulicity. Revenue outside the U.S. was $76.6 million, primarily driven by uptake in Europe and Japan. For the first quarter of 2017, worldwide Cyramza revenue was $171.2 million, an increase of 31 percent compared with the first quarter of 2016. U.S. revenue was $66.2 million, a decrease of 8 percent, driven by lower realized prices and, to a lesser extent, decreased demand due to competitive pressure. Revenue outside the U.S. was $105.1 million, an increase of 77 percent, primarily due to strong volume growth in Japan, partially offset by lower realized prices. For the first quarter of 2017, Taltz, a treatment for moderate-to-severe plaque psoriasis, generated worldwide revenue of $96.6 million. U.S. revenue was $87.8 million, an increase of $28.4 million compared with the fourth quarter of 2016, reflecting strong launch uptake. The company's worldwide Jardiance revenue during the first quarter of 2017 was $74.0 million, an increase of 94 percent compared with the first quarter of 2016. U.S. revenue increased 60 percent, to $47.7 million, driven by increased share of market for Jardiance and growth in the SGLT2 class. Revenue outside the U.S. was $26.2 million. Jardiance is part of the company's alliance with Boehringer Ingelheim, and Lilly reports as revenue a portion of Jardiance's gross margin. For the first quarter of 2017, Basaglar generated worldwide revenue of $46.0 million. U.S. revenue was $22.0 million. Basaglar is part of the company's alliance with Boehringer Ingelheim, and Lilly reports as revenue total sales, with payments made to Boehringer Ingelheim for its portion of the gross margin reported as cost of sales. For the first quarter of 2017, Lartruvo, a treatment in combination with doxorubicin for a subset of adult patients with advanced soft tissue sarcoma, generated worldwide revenue of $42.1 million. U.S. revenue was $38.1 million, an increase of $26.7 million compared with the fourth quarter of 2016. For the first quarter of 2017, Olumiant, a treatment for moderate-to-severe rheumatoid arthritis, generated worldwide revenue of $1.9 million, reflecting initial sales in Germany. In the first quarter of 2017, worldwide animal health revenue totaled $769.4 million, an increase of 2 percent compared with the first quarter of 2016. Worldwide food animal revenue decreased 3 percent, to $508.1 million, driven by lower worldwide volume due to continued economic pressure in the dairy market and customer buying patterns. Worldwide companion animal revenue increased 13 percent, to $261.3 million, driven by the inclusion of $40.8 million in revenue from the acquisition of Boehringer Ingelheim Vetmedica's U.S. feline, canine and rabies vaccine portfolio, partially offset by worldwide competitive pressure. Earnings per share for 2017 are being revised to be in the range of $2.60 to $2.70 on a reported basis, due to severance costs incurred as a result of actions taken to reduce the company's cost structure. Earnings per share for 2017 are being reaffirmed to be $4.05 to $4.15 on a non-GAAP basis. The company still anticipates 2017 revenue between $21.8 billion and $22.3 billion. Excluding the impact of foreign exchange rates, the company expects revenue growth from animal health products and a number of established pharmaceutical products including Trajenta®, Forteo and Humalog, as well as higher revenue from new products including Trulicity, Taltz, Basaglar, Cyramza, Jardiance and Lartruvo. Marketing, selling and administrative expenses are still expected to be in the range of $6.4 billion to $6.6 billion. Research and development expenses are still expected to be in the range of $4.9 billion to $5.1 billion. The 2017 tax rate is still expected to be approximately 24.5 percent on a reported basis and 22.0 percent on a non-GAAP basis. The following table summarizes the company's 2017 financial guidance: As previously announced, investors and the general public can access a live webcast of the first-quarter 2017 financial results conference call through a link on Lilly's website at https://investor.lilly.com/events.cfm. The conference call will begin at 9 a.m. Eastern Time (ET) on Tuesday, April 25, 2017, and will be available for replay via the website. Lilly is a global healthcare leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at www.lilly.com and http://newsroom.lilly.com/social-channels. F-LLY This press release contains management's current intentions and expectations for the future, all of which are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. The words "estimate," "project," "intend," "expect," "believe," "target," "anticipate," and similar expressions are intended to identify forward-looking statements. Actual results may differ materially from these forward-looking statements due to various factors. There are significant risks and uncertainties in pharmaceutical research and development. There can be no guarantees that pipeline products will succeed in clinical testing, will receive the necessary clinical and manufacturing regulatory approvals, or will prove to be commercially successful. The company's results may also be affected by such factors as the timing of anticipated regulatory approvals and launches of new products; market uptake of recently launched products; competitive developments affecting current products; the expiration of intellectual property protection for certain of the company's products; the company's ability to protect and enforce patents and other intellectual property; the impact of governmental actions regarding pricing, importation, and reimbursement for pharmaceuticals, including U.S. health care reform; regulatory compliance problems or government investigations; regulatory actions regarding currently marketed products; unexpected safety or efficacy concerns associated with the company's products; issues with product supply stemming from manufacturing difficulties or disruptions; regulatory changes or other developments; changes in patent law or regulations related to data-package exclusivity; litigation involving current or future products; the extent to which third-party indemnification obligations relating to product liability litigation and similar matters will be performed; unauthorized disclosure of trade secrets or other confidential data stored in the company's information systems and networks; changes in tax law and regulations; changes in inflation, interest rates, and foreign currency exchange rates; asset impairments and restructuring charges; changes in accounting standards promulgated by the Financial Accounting Standards Board and the U.S. Securities and Exchange Commission (SEC); acquisitions and business development transactions and related integration considerations; and the impact of exchange rates and global macroeconomic conditions, including the effect of the pending exit of the United Kingdom from the European Union. For additional information about the factors that could cause actual results to differ materially from forward-looking statements, please see the company's latest Form 10-K filed with the SEC. You should not place undue reliance on forward-looking statements, which speak only as of the date of this release. Except as is required by law, the company expressly disclaims any obligation to publicly release any revisions to forward-looking statements to reflect events after the date of this release.        Alimta(R) (pemetrexed disodium, Lilly)     Basaglar(R) (insulin glargine injection, Lilly)     Cialis(R) (tadalafil, Lilly)     Cymbalta(R) (duloxetine hydrochloride, Lilly)     Cyramza(R) (ramucirumab, Lilly)     Effient(R) (prasugrel, Lilly)     Erbitux(R) (cetuximab, Lilly)     Forteo(R) (teriparatide of recombinant DNA origin injection, Lilly)     Glyxambi(R) (empagliflozin/linagliptin, Boehringer Ingelheim)     Humalog(R) (insulin lispro injection of recombinant DNA origin, Lilly)     Humulin(R) (human insulin of recombinant DNA origin, Lilly)     Jardiance(R) (empagliflozin, Boehringer Ingelheim)     Lartruvo(TM) (olaratumab, Lilly)     Olumiant(R) (baricitinib, Lilly)     Portrazza(R) (necitumumab, Lilly)     Stelara(R) (ustekinumab, Janssen Biotech)     Strattera(R) (atomoxetine hydrochloride, Lilly)     Synjardy(R) (empagliflozin/metformin, Boehringer Ingelheim)     Taltz(R) (ixekizumab, Lilly)     Trajenta(R) (linagliptin, Boehringer Ingelheim)     Trulicity(R) (dulaglutide, Lilly)     Zyprexa(R) (olanzapine, Lilly)       Eli Lilly and Company Employment     Information This is a disclosure announcement from PR Newswire.


News Article | May 3, 2017
Site: www.prnewswire.com

In his role at the alternative investments management firm Altamar, Fernandez is focused on the design, fundraising and management of Altamar's Credit Business and is a member of the Investment Committee of Alta Life Sciences, a life sciences venture fund with a Spanish and European focus launched in 2016. Fernandez has also worked as Managing Director at Credit Agricole Corporate and Investment Bank, and as a consultant for the World Bank as a securities and debt capital markets expert. Fernandez has also served on the Board of Directors of the European Investment Bank and as a Board Member of CESCE (Spain's export credit agency). Between 2010 and 2013, he worked for Professor Andrew W. Lo at MIT's Laboratory for Financial Engineering on the biomedical megafund project. He has authored various papers on this field, focusing on the use of securitization techniques to spur investments in early stage drug development for critical diseases. Fernandez holds an MBA from MIT Sloan (Sloan Fellows Program in Innovation and Global Leadership), a Masters in Finance from the London Business School, a Masters in Portfolio Management degree from I.E.B. and Bachelor's Degree in Economics and Business from CUNEF (Madrid). "I have a passion for using financial engineering to solve problems and create a better, more sustainable world, and I believe that my goals and dreams align well with the mission of the Human Vaccines Project," said Fernandez. "I am eager to start my work in support of the Human Vaccines Project as the organization advances research in an area that is critical to the future of human health – decoding the human immune system to understand why and how it works to help the body combat diseases." About the Human Vaccines Project The Human Vaccines Project is a nonprofit public-private partnership with a mission to decode the human immune system to accelerate the development of vaccines and immunotherapies against major infectious diseases and cancers. The Project brings together leading academic research centers, industrial partners, nonprofits and governments to address the primary scientific barriers to developing new vaccines and immunotherapies. Support and funding for the Project includes the Robert Wood Johnson Foundation, John D. and Catherine T. MacArthur Foundation, GSK, MedImmune, Sanofi Pasteur, Crucell/Janssen, Regeneron, Pfizer, Moderna, Boehringer Ingelheim, Aeras, Vanderbilt University Medical Center, UC San Diego, The Scripps Research Institute, J. Craig Venter Institute and La Jolla Institute for Allergy and Immunology. To learn more, visit www.humanvaccinesproject.org. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/jose-maria-fernandez-joins-the-human-vaccines-project-board-of-directors-300450282.html


Global Anti-Hypertensive Drugs Market Information, by Pharmacological Class (Diuretics, ACE Inhibitors, Calcium Channel Blockers, Adrenergic Blocker, etc.), by Hypertension Type (Systemic and Pulmonary Hypertension Drugs), by Disease Source (Primary and Secondary) - Forecast till 2022Pune, India - April 24, 2017 /MarketersMedia/ — Market Forecast: Market Research Future published a half-cooked research report on Global Anti-Hypertensive Drug Market. The Global Anti-Hypertensive Drug Market is expected to grow at a CAGR of ~2.73 % during the period 2016 to 2022. Market Highlights Anti-Hypertensive Drugs are used for the treatment of high blood pressure arising due to several factors. The Anti-Hypertensive Drug Market is characterised by low rate of return on most drugs due to greater penetration of generics due to loss of patents of major blockbusters. Thus the strategy of most companies revolve around same for less or more for more. Availability of a number of effective substitute and fragmentation of market along with good efficacy and cost effectiveness of traditional anti-hypertensive drugs act as a drag on charging a premium. This also reduces any propensity of volatility in the future market unless the development of drug having a special property such as additional benefit for patients suffering from other diseases. Thus a premium can be charged on special anti-hypertensive drugs such as /angiotensin II receptor blockers (ARBs) and ACE inhibitors which prolong survival in patients with congestive heart failure and diabetes mellitus. Thus combination therapy will be on the rise. The uptake of any newer drug will be slow in face of competition and apprehensions about its safety, efficacy and special benefit potential. Thus marketing cost will tend to be higher further reducing profits. Request to Receive a Sample Copy @ https://www.marketresearchfuture.com/sample_request/2347 Key Players: The major participants of this market are: Novartis AG, Daiichi Sankyo Company Ltd., Astra Zeneca plc, Sanofi S.A., Pfizer Inc., Acetelion Ltd, Merck & Co., Boehringer Ingelheim, Lupin Ltd., Johnson & Johnson Ltd., Ranbaxy Laboratories Ltd., Inc., Takeda Pharmaceutical, Bayer AG etc. Regional Analysis: Depending on geographic region, Anti-Hypertensive Drug Market is segmented into four key regions: Americas, Europe, Asia Pacific, and Middle East & Africa. Globally developed countries led by North America is the largest market for Anti-hypertensive drugs. Europe is the second-largest market for anti-hypertensive drugs. The developed region will lose the lead to the developing in the nearest future. Anti-hypertensive drugs will be one of the greatest beneficiaries of the disease shift from developed to developing regions. But there seems to be no greater benefit except greater sales to the companies. Access Report Page @ https://www.marketresearchfuture.com/reports/anti-hypertensive-drugs-market-2347 Market Analysis: The global Anti-Hypertensive Drug Market has been laggard as can be seen from historical data and it is expected to continue in the future. The global Anti-Hypertensive Drug Market is expected to grow with a sluggish CAGR of ~ 2.73 % during the forecasted period. Segmentation: Global anti-hypertensive drugs market has been segmented on the basis of pharmacological class which comprises diuretics, ace inhibitors, calcium channel blockers, adrenergic blockers, central sympatholytic, renin inhibitors and vasodilators. On the basis of application; market is segmented into primary or essential hypertension and secondary hypertension. On the basis of hypertension type into systemic hypertension drugs and pulmonary hypertension drugs Make an Enquiry for Report @ https://www.marketresearchfuture.com/enquiry/2347 About Market Research Future: At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services. MRFR team have supreme objective to provide the optimum quality market research and intelligence services to our clients. Our market research studies by products, services, technologies, applications, end users, and market players for global, regional, and country level market segments, enable our clients to see more, know more, and do more, which help to answer all their most important questions. In order to stay updated with technology and work process of the industry, MRFR often plans & conducts meet with the industry experts and industrial visits for its research analyst members. Contact Info:Name: Akash AnandEmail: akash.anand@marketresearchfuture.comOrganization: Market Research Future (MRFR)Address: Office No. 528, Amanora Chambers Magarpatta Road, Hadapsar, Pune - 411028 Maharashtra, IndiaPhone: +1 646 845 9312Source URL: http://marketersmedia.com/anti-hypertensive-drugs-market-applications-and-forecast-global-market-to-grow-at-a-cagr-of-2-73-from-2016-to-2022/189581For more information, please visit https://www.marketresearchfuture.com/reports/anti-hypertensive-drugs-market-2347Source: MarketersMediaRelease ID: 189581


Patent
Boehringer Ingelheim GmbH | Date: 2012-11-14

The present invention relates to anti-IL-36R binding compounds, in particular new anti-IL-36R antibodies and therapeutic and diagnostic methods and compositions for using the same.


Patent
Vectura Delivery Devices Ltd and Boehringer Ingelheim GmbH | Date: 2014-09-11

A passive inhaler for delivery of a powder-form inhalation formulation from a blister strip with a plurality of blister pockets is proposed. The inhaler comprises an impaction element onto which the air stream can impact together with entrained inhalation formulation for better deagglomeration. Alternatively, the inhaler comprises an oscillating and/or vibrating device for better de-agglomeration of the inhalation formulation. Alternatively or additionally, the inhaler comprises one or two mixing means for generating swirls, preferably with opposite rotation directions.


Patent
Boehringer Ingelheim GmbH | Date: 2013-05-17

The invention relates to a system composed of an inhaler and a capsule, preferably intended for single use. The capsule contains a preferably powdered pharmaceutical preparation which, for inhalation, is expelled from the capsule through at least one hole. The capsule comprises as capsule elements a capsule cap and a capsule body, at least one of which comprises at least one prefabricated hole. The prefabricated hole in the capsule is sealed off in the transporting state of the system and is open in the usage state. The hole is exposed by actuation of a pulling mechanism. Prior to this the hole is closed off by a capsule receptacle or a film. In one embodiment the capsule may be present in two different states, for example in different insertion positions of the capsule elements. In the first state the prefabricated hole is closed off and in the second it is exposed. Also shown is an inhaler suitable as a disposable product, which is manufactured from thermoformed parts or from blister film.

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