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News Article | April 26, 2017
Site: marketersmedia.com

— Global Lower Extremities Market 2017-2021 is growing popularity of MI procedures. Traditional open surgeries can cause post-operation complications such as pain, partially collapsed lungs, blood clots, fatigue, muscle atrophy, and infections. The anesthesia administered before surgeries can cause nausea, sore throat, confusion, and sleepiness. To reduce such complications, medical facilities have started implementing MI techniques in their surgical procedures. Complete report on lower extremities market spread across 70 pages, analyzing 3 major companies and provides 58 data exhibits is now available at http://www.reportsnreports.com/reports/966148-global-lower-extremities-market-2017-2021.html . The report, Global Lower Extremities Market 2017-2021, has been prepared based on an in-depth market analysis with inputs from industry experts. This report covers the market landscape and its growth prospects over the coming years. The report also includes a discussion of the key vendors operating in this market. According to the lower extremities market report, one driver in market is hip replacement procedures in UK. The joint replacement surgeries such as hip and knee replacement and revision procedures are increasing the need for lower extremity products in the market. For the replacement procedure, artificial implants are used, which replaces the joints in hip and knees. In 2002, the National Joint Registry was set up by the Department of Health and Welsh Government, UK. The registry collects the orthopedic reconstruction data from the NHS and procedures performed in the NHS hospitals. According to the National Joint Registry, the number of revision hip replacement procedures performed in 2014 and 2015 were 8,176 and 7,214, respectively. For hip replacement revision cases, a dip in the number of cases was observed in 2015 owing to the increased use of advanced lower extremity products. The analysts forecast global lower extremities market to grow at a CAGR of 7.66% during the period 2017-2021. Key players in the global lower extremities market: DePuy Synthes, Stryker, and Zimmer Biomet. Other Prominent Vendors in the market are: Active Implants, Acumed, Arthrex, Avitus Orthopaedics, Biotech Limb and Brace, Bioventus, Bone Therapeutics, Bone Biologics, Ceramisys, ConforMIS, CONMED, CollPlant, DJO Global, Evolutis, Exactech, FH Orthopedics, Graftys, ICONACY Orthopedic Implants, Integra LifeSciences, implantcast, Isto Biologics , Lima Corporate, Medtronic, Merete Group, Össur, OsteoMed, Orthofix, Orthogem, Promedics Orthopaedic, Regenexx,, RTI Surgical, Sigma Graft, Silver Bullet Therapeutics, Skye Biologics, Smith & Nephew, Stanmore Implants Worldwide, Surgical Appliance Industries, Wright Medical Group, and Xtant Medical. Further, the report states that one challenges in market is high procedure cost. Hospitals and surgical centers are under constant pressure to deliver quality care at low cost. However, this has become difficult due to the implementation of advanced procedures that involve the use of sophisticated devices. Hospitals and ASCs need to consider various procurement processes and budget allocation considerations before purchasing such devices. To increase their budget, hospitals sometimes implement the procedure cost, which can be high for the individuals. It increases cost burden on them, which hinders the market adoption. High procedure cost can impact the market growth negatively. About Us: ReportsnReports.com is single source for all market research needs. Our database includes 500,000+ market research reports from over 100+ leading global publishers & in-depth market research studies of over 5000 micro markets. With comprehensive information about the publishers and the industries for which they publish market research reports, we help in purchase decision by mapping your information needs with our huge collection of reports. For more information, please visit http://www.reportsnreports.com/reports/966148-global-lower-extremities-market-2017-2021.html


News Article | April 24, 2017
Site: www.businesswire.com

DURHAM, N.C.--(BUSINESS WIRE)--Bioventus has named David Varner Vice President of Marketing, Active Healing Therapies.


Systems and methods for preparing osteoinductive synthetic bone grafts are provided in which a porous ceramic granule is loaded with an osteoinductive material, and then placed in contact with a biocompatible matrix material.


Patent
Mathys AG Bettlach and Bioventus | Date: 2017-04-26

The method is for producing porous calcium deficient hydroxyapatite granules and comprises the following steps: (a) subjecting granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD) or calcium sulfate hemihydrate (CSH), the granules comprising interconnected pores with a minimum mean diameter of 3 microns, to a first incubation in an alkaline aqueous solution having a pH-value of less than 10 and containing PO43- ions; (b) subjecting the granules to a second incubation in an alkaline aqueous solution having a pH-value of more than 10 and optionally PO43- ions; (c) filtering and drying the obtained porous granules of calcium deficient hydroxyapatite; and wherein (d) the sum of the amounts of PO43- ions present in the first and second incubation is at least as large as the amount of SO42- ions of the granules used for step (a). The porous calcium deficient hydroxyapatite granules obtained by the invention may be purposefully used as carriers for biologically active substances in particular for proteins.


Patent
Mathys Ag Bettlach and Bioventus | Date: 2015-06-22

The method is for producing porous calcium deficient hydroxyapatite granules and comprises the following steps: (a) subjecting granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD) or calcium sulfate hemihydrate (CSH) to an incubation in an alkaline aqueous solution having a pH-value of less than 10 and containing PO_(4)^(3) ions; whereby the granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD) or calcium sulfate hemihydrate (CSH) comprise interconnected pores with a minimum mean diameter of 3 microns; (b) washing with water the granules obtained after incubation of step a); (c) drying the obtained porous granules of calcium deficient hydroxyapatite; whereby (d) the amount-of PO_(4)^(3) ions present in the incubation of step a) is at least as large as the amount of SO_(4)^(2) ions of the granules used for step (a). The porous calcium deficient hydroxyapatite granules obtained by the invention may be purposefully used as carriers for biologically active substances in particular for proteins.


Patent
Mathys AG Bettlach and Bioventus | Date: 2017-04-26

The method is for producing porous calcium deficient hydroxyapatite granules and comprises the following steps: (a) subjecting granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD) or calcium sulfate hemihydrate (CSH) to an incubation in an alkaline aqueous solution having a pH-value of less than 10 and containing PO43- ions; whereby the granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD) or calcium sulfate hemihydrate (CSH) comprise interconnected pores with a minimum mean diameter of 3 microns; (b) washing with water the granules obtained after incubation of step a); (c) drying the obtained porous granules of calcium deficient hydroxyapatite; whereby (d) the amount-of PO43- ions present in the incubation of step a) is at least as large as the amount of SO42- ions of the granules used for step (a). The porous calcium deficient hydroxyapatite granules obtained by the invention may be purposefully used as carriers for biologically active substances in particular for proteins.


Patent
Bioventus and Fujifilm Co. | Date: 2016-10-21

Methods of purifying TGF- superfamily proteins, including osteogenic proteins such as bone morphogenetic proteins (BMPs), are disclosed.


Patent
Bioventus | Date: 2016-12-30

The present disclosure relates to compositions useful in synthetic bone graft applications. Particularly, the disclosure teaches moldable bone graft compositions, methods of making said compositions, and methods of utilizing the same.


Patent
Bioventus and Mathys Ag Bettlach | Date: 2014-06-23

The method is for producing porous calcium deficient hydroxyapatite granules and comprises the following steps: (a) subjecting granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD) or calcium sulfate hemihydrate (CSH), the granules comprising interconnected pores with a minimum mean diameter of 3 microns, to a first incubation in an alkaline aqueous solution having a pH-value of less than 10 and containing PO_(4)^(3) ions; (b) subjecting the granules to a second incubation in an alkaline aqueous solution having a pH-value of more than 10 and optionally PO_(4)^(3) ions; (c) filtering and drying the obtained porous granules of calcium deficient hydroxyapatite; and wherein (d) the sum of the amounts of PO_(4)^(3) ions present in the first and second incubation is at least as large as the amount of SO_(4)^(2) ions of the granules used for step (a). The porous calcium deficient hydroxyapatite granules obtained by the invention may be purposefully used as carriers for biologically active substances in particular for proteins.


Patent
Bioventus | Date: 2016-02-04

Disclosed are various bioactive grafts and methods of making the same. In one embodiment, bone material is harvested from a donor. The harvested bone material is exposed to a lysing agent, the lysing agent configured to release growth factors and bioactive materials from cellular material of the harvested bone material. The harvested bone material is then rinsed with a rinsing agent. The pH of the harvested bone material is substantially neutralized.

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