Epidemiology Biostatistics and Committees Unit Instituto Giannina Gaslini Genoa Italy

Genoa Italy, Italy

Epidemiology Biostatistics and Committees Unit Instituto Giannina Gaslini Genoa Italy

Genoa Italy, Italy
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Bagnasco F.,Epidemiology Biostatistics and Committees Unit Instituto Giannina Gaslini Genoa Italy
Pediatric Transplantation | Year: 2017

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the treatment of choice for a variety of congenital disorders. We report the experience of children affected by congenital diseases other than bone marrow failure syndromes who received allo-HSCT over a period of 25 years at G. Gaslini Paediatric Research Institute. HSCTs were performed in 57 children with congenital diseases (25 with congenital immunodeficiencies, 10 with severe combined immunodeficiencies, and 22 with metabolic diseases). Overall survival rate at 3 years in the whole group of patients was 76.9%, with a trend in favor of better outcome in children with metabolic diseases and in those who received cord blood cells (85.9%) vs bone marrow cells (72.4%). © 2017 John Wiley & Sons A/S.

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